Research

Ambroise is a PhD student at Cheikh Anta Diop University (Senegal) in the Department of Microbiology. He conducts research in the laboratory of Professor Souleymane Mboup at Le Dantec Hospital. Ambroise conducted his Masters dissertation research in the laboratory of Professor Mboup studying viral diagnostic techniques and evaluating HIV rapid test efficacy. As a PhD student, Ambroise has studied P. falciparum merozoite invasion and immune mediated mechanisms of invasion inhibition in Senegal, The Gambia, and Boston as a Fogarty trainee with Professor Dyann Wirth. Ambroise identified a large genetic deletion in a major invasion ligand—PfRh2b—in Senegal and has been studying the impact of this deletion on invasion pathway and immune mediated invasion inhibition. Ambroise’s work is multidisciplinary and he has combined approaches in molecular biology with population genetics, epidemiology, and immunology to study the dynamics of polymorphisms in important Plasmodium falciparum invasion ligands in global parasite populations.