Dr Choi’s research focuses on the effects of environmental exposures on health outcomes. She has been studying the birth cohorts in the Faroe Islands where exposures to environmental chemicals including mercury, PCBs, and PFCs are increased due to traditional marine diets. In addition, she also studies the effects of the contaminants on cardiovascular function and type 2 diabetes among the Faroese septuagenarians. She is also actively involved in the research on the impact of nutrients as possible negative confounders that may have caused an underestimation of methylmercury toxicity. Dr Choi’s other research interests include studying the adverse effects of fluoride exposure in children.
Choi AL, Levy JI, Dockery DW, Ryan LM, Tolbert PE, Altshul LM, Korrick SA. 2006. Does Living near a superfund site contribute to higher polychlorinated biphenyl (PCB) exposure? Environ Health Perspect 114:1092-1098.
Choi AL, Budtz-Jørgensen E, Jørgensen PJ, SteuerwaldU, DebesF, Weihe P, GrandjeanP. Selenium as a potential protective factor against mercury developmental neurotoxicity. 2008. Env Res. 107:45-52.
Choi AL, Cordier S, Weihe P, Grandjean P. Negative confounding in the evaluation of toxicity: the case of methylmercury in fish and seafood. Crit Rev Toxicol. 2008. 38:877-893.
Choi AL, Grandjean P. Methylmercury exposure and health effects in humans. 2008. Environ Chem. 5:112-120
Grandjean P, Choi A. The delayed appearance of a mercurial warning. 2008. Epidemiology. 19:10-11.
Sagiv SK, Nugent JK, Brazelton TB, Choi AL, Tolbert PE, Altshul LM, Korrick SA. Prenatal organochlorine exposure and measures of behavior in infancy using the neonatal behavioral assessment scale (NBAS). Environ Health Perspect. 2008. 116:666-673.
PetersenMS, Weihe P, Choi A, Grandjean P. Increased prenatal exposure to methylmercury does not affect the risk of Parkinson’s disease. Neurotoxicol 2008; 29:591-595.
Choi AL, Weihe P, Budtz-Jørgensen E, Jørgensen PJ, Salonen JT, Tuomainen TP, Murata K, Nielsen HP, Petersen MS, Askham J, Grandjean P. Methylmercury exposure and adverse cardiovascular effects in Faroese whalingmen. Environ Health Perspect. 2009. 117:367-372.
Julvez J, Debes F, Weihe P, Choi A, Grandjean P. Sensitivity of continuous performance tests (CPT) at age 14 years to developmental methylmercury exposure. Neurotoxicol Teratol 2010. 32:627-632.
Grandjean P, Choi AL, Weihe P, Murata K. Methylmercury neurotoxicology: from rare poisonings to silent pandemic. In: Developmental Neurotoxicoly Research: Principles, Models, Techniques, Strategies, and Mechanisms. Wang C, Slikker W. Eds. NJ: Wiley. 2011. pp. 335-356.
Julvez J, Debes F, Weihe P, Choi AL, Grandjean P. Thyroid dysfunction as a mediator of organochlorine neurotoxicity in preschool children. Environ Health Perspect. 2011. 119:1429-1435. PMID: 21719373.
Grandjean P, Henriksen JE, Choi AL, Petersen MS, Dalgård C, Nielsen F, Weihe P. Marine food pollutants as a risk factor for hypoinsulinemia and type 2 diabetes. Epidemiol. 2011. 22:410-417.
Mahaffey KR, Sunderland EM, Chan HM, Choi AL, Grandjean P, Mariën K, Oken E, Sakamoto M, Schoeny R, Weihe P, Yan C-H, Yasutake A. Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption. Nutr Rev 2011. 69:493-508.
Julvez J, Takashi Y, Choi AL, Grandjean P. Epidemiological evidence on methylmercury neurotoxicity. In: Ceccatelli S, Aschner M, eds. Methylmercury and neurotoxicity. NY: Springer 2012. pp. 13-35.
Karagas MR, Choi AL, Oken E, Horvat M, Schoeny R, Kamai E et al. Evidence on the human health effects of low level methylmercury exposure. Environ Health Perspect 2012. 120:799-806.
Oken E, Choi AL, Karagas MR, Mariën K, Rheinberger CM, Schoeny R et al. Which fish should I eat? Perspectives influencing fish consumption choices. Environ Health Perspect 2012.
Mason RP, Choi AL, Fitzgerald WF, Hammerschmidt CR, Lamborg C, Sunderland EM. Mercury biogeochemical cycling in the ocean and policy implications. Environ Res. 2012.
Choi AL, Grandjean P. Human health significance of dietary exposures to methylmercury. In: Liu G, Cai Y, O’Driscoll, eds. Environmental chemistry and toxicology of mercury. NJ: Wiley. 2012. pp. 545-568.
Choi AL, Sun GF, Zhang Y, Grandjean P. Developmental fluoride neurotoxicity: a systematic review and meta-analysis. Environ Health Perspect 2012. Epub ahead of print.