The Laboratory of Human Environmental Epigenetics investigates molecular mechanisms and biomarkers that reflect reprogramming of health and disease trajectories in response to environmental exposures. The laboratory research spans across epigenomics, environmental mitochondriomics, and computational epigenomics.
The laboratory’s resources and expertise are dedicated to the investigation of the epigenome and mitochondriome at different life stages ranging from fetal life to aging populations. Developing and applying novel molecular methods in human populations is a primary endeavor in the lab. Recent and ongoing projects investigate effects from environmental exposures, including particulate air pollution, metals, Bisphenol A, phthalates, and pesticides, and common risk factors, such as psychosocial violence, second-hand smoking, and alcohol abuse. The laboratory has conducted studies in the U.S., as well as in highly-exposed groups or special conditions of exposure in China, Canada, Mexico, Italy, Poland, Thailand, Oman, Bulgaria, Russia, and other countries.