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RESEARCH: HIV Prevention

HPTN052: A Randomized Trial to Evaluate the Effectiveness of Antiretroviral Therapy plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples
BHP032

Principal Investigators: Max Essex & Joseph Makhema

Objectives:
To determine whether antiretroviral therapy (ART) can prevent the sexual transmission of HIV-1 in HIV-1 serodiscordant couples. This study is a Phase III, two-arm, randomized, controlled, multi-center trial.

Enrollment: April 2009–May 2010

Follow Up:
Ongoing

Publications:
Using HIV viral load to guide treatment-for-prevention interventions. Curr Opin HIV AIDS. 2012 Jan 16. [Epub ahead of print]

Prevention of HIV-1 Infection with Early Antiretroviral Therapy. N Engl J Med. Aug 11; 365(6):493-505 (2011)

 

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