Conference on Statistical and Epidemiologic Issues in Multiple Sclerosis

April 27, 2007

Abstracts are linked to talk titles


  7:45 am - 8:30 am
Continental Breakfast
  8:30 am - 8:45 am
Rebecca Betensky, Professor of Biostatistics, Harvard School of Public Health, Boston, Massachusetts
    Welcome

Session 1: Keynote Address

8:45 am - 9:15 am
Howard Weiner, Robert L. Kroc Professor of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts
   
The Study of Multiple Sclerosis in 2007: Unanswered Questions and Future Directions
Session 2: Issues in Study Design for MS
  9:15 am - 9:20 am
Alberto Ascherio, Associate Professor of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts
   
Introduction
  9:20 am - 9:50 am
Philip De Jager, Assistant Professor of Neurology, Harvard Medical School, Boston, Massachusetts
    Recognizing Population Structure in Relapsing-Remitting MS
  9:50 am - 10:00 am Discussion
  10:00 am - 10:20 am
Break
10:20 am - 10:50 am
Alberto Ascherio, Associate Professor of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts
   
Prospective Studies in MS
  10:50 am - 11:00 am Discussion
  11:00 am - 11:30 am
Yinshan Zhao, Research Associate, University of British Columbia MS/MRI Research Group, British Columbia, Canada
   
Short-term changes in gadolinium enhancing lesion activity in relapsing-remitting multiple sclerosis: implications for clinical trial design
  11:30 am - 12:00 pm
Discussion
  12:00 pm - 1:00 pm
Lunch
Session 3: Vitamin D and MS
1:00 pm - 1:05 pm
Alberto Ascherio, Associate Professor of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts
   
Introduction
  1:05 pm - 1:35 pm
Ed Giovannucci, Professor of Epidemiology and Nutrition, Harvard School of Public Health, Boston, Massachusetts
   
Assessment of Vitamin D Exposure in Epidemiologic Studies
  1:35 pm - 2:05 pm
Sue Hankinson, Associate Professor of Medicine, Harvard Medical School, Boston, Massachusetts
   
Using Biomarkers in Epidemiologic Research: 25(OH)D as an Example
  2:05 pm - 2:35 pm
Donna Spiegelman, Professor of Epidemiologic Methods, Harvard School of Public Health, Boston, Massachusetts
   
Statistical Analysis of Biomarkers in Epidemiological Research: 25(OH)D as an Example
  2:35 pm - 3:05 pm
George Ebers, Action Research Professor, University of Oxford, Oxford, United Kingdom
   
Challenges in Conducting a Primary Prevention Trial: Vitamin D and MS
  3:05 pm - 3:20 pm
Discussion
  3:20 pm - 3:40 pm

Break

Session 4: Methods for Analysis of MS Progression
3:40 pm - 3:45 pm

Rebecca Betensky, Professor of Biostatistics, Harvard School of Public Health, Boston, Massachusetts

   
Introduction
  3:45 pm - 4:15 pm
John Petkau, Professor of Statistics, University of British Columbia, Vancouver, British Columbia, Canada
   
Statistical Evaluation of Progression in MS Clinical Trials
  4:15 pm - 4:45 pm
Gary Cutter, Professor of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama
   
If "Insanity is doing the same thing in the same way & expecting a different outcome", What's Sane about MS Outcome Measures?
  4:45 pm - 5:15 pm
Micha Mandel, Lecturer in Statistics, Hebrew University, Jerusalem, Israel
   
Estimating Time to Progression Using Longitudinal EDSS Data
  5:15 pm - 5:30 pm
Discussion