2006 Summer Program in Quantitative Sciences
for Public Health Research
Group Projects and Mentors
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Faculty Mentor: Dr.
Sonia Hernandez Diaz Project Title: Childhood Malnutrition and Postwar Reconstruction in Rural El Salvador Project Description: In 1998, six
years after the peace agreement that concluded the Civil War in El Salvador,
a study attempted to describe the association between the reconstruction
effort and child health in one rural area, using child nutrition as an
indicator. The hypotheses were: (1) prevalence of childhood malnutrition,
in the form of stunting, was still high even where large amounts of post-war
reconstruction aid had been received, and (2) delays in both implementation
of the post-war land transfer process and provision of basic services
to the target population were associated with child malnutrition. In this
project, students described associations between post-war social and economic
assistance programs, and child health status as reflected by nutrition
in a population of resettled rural refugees. Students used descriptive
analysis and univariate tests to evaluate associations between socioeconomic
factors and stunting, and multivariate logistic regression to estimate
adjusted odds ratios and their 95% confidence intervals. |
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Faculty Mentor: Dr.
Stuart Lipsitz Project Title: Differences in Nutritional Intake Between Black and White Males Presenting for Prostate Cancer Screening Project Description: Increasing evidence suggests that diet and nutrition modify the risk of each of certain cancers, and in particular, prostate cancer. In the U.S. during 1988-1992, the incidence rates of prostate, stomach, oral cancer, and lung cancer were 31%, 86%, 35%, and 48% higher in black males than white males. Although differences in other risk factors (including smoking) account for much of the racial diversity in incidence of these cancers, it is possible that some of the racial differences in cancer risk and mortality, particularly for prostate cancer, may be related to differences in nutrition. During the project, students tested for differences in reported dietary intake between black and white males who attended a prostate cancer screening using descriptive analyses including medians, non-parametric tests for differences between nutritional intake black and white males, age-adjusted medians for blacks and whites using median regression analyses. |
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Faculty Mentor: Dr.
Jonathan Levy Project Title: Indoor and Outdoor
Polycyclic Aromatic Hydrocarbon Concentrations in Urban Neighborhoods |
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Faculty Mentor:
Dr. Christoph Lange Project Title: Determining Genetic Determinants of Alcoholism using Family-Based Association Testing (FBAT) Project Description: In this research project, students used Family-Based Association Testing (FBAT) to investigate genetic determinants of alcoholism. FBATs can generally be defined as a class of tests that use family data to examine whether genetic variation across individuals may be used to explain corresponding phenotypic (or disease) variation. Students applied these tests to the Collaborative Study on the Genetics of Alcholism (COGA), which contains genetic and phenotype information on approximately 1600 family members. The goal of the project was to identify any significant genetic markers of alcoholism (or surrogate phenotypic traits). For the analysis, students selected the appropriate tests in PBA and used the FBAT screening process to find the most promising SNPs for analysis. |
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