2007 Summer Program in Quantitative Sciences for
Public Health Research
Group Projects and Mentors
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Faculty Mentor: Dr.Yi Li Project Title: The Effects of Endotoxin Exposure in Households Project Description: This research project was on endotoxin levels and their effect on asthma in infants. Based on the Home Allergen Study, the students determined that there was no seasonal effect on endotoxin levels. However, they were unable to find a correlation between endotoxin levels and the incidence of asthma in the infants. Additionaly, they found that during the 1990's the mean endotoxin level was significantly diffferent from the mean endotoxin level for the 2000's.
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Faculty Mentor: Dr. Louise Ryan
Project Title: Phthalate Exposure and its Effect on Sperm Quality Project Description: This research project was looking into identifying whether there was an association between men's exposure to phthalates (a common chemical used to increase the flexibility of plastic) and their sperm quality. Phthlates have been associated with reproductive problems in animals, hence the motivation of asking the question: could pthalates affect sperm quality in men?The research revealed an inverse relationship between age and semen volume and a direct relationship between sperm concentration and the phthalate MEHP. Though many questions are left to be answered, there is evidence that some phthlates do adversely affect sperm quality in men. Also, morphology [in percentage of normally shaped] was inversely related with the increase of abstinence time. |
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Faculty Mentor: Dr.
Christoph Lange Project Title: Genetic Determinants of Alcoholism Project Description: This project used regression models to investigate genetic determinants of alcoholism. They applied multivariate regression models to the Collaborative Study on the Genetics of Alcoholism (COGA), which contains genetic and phenotype information on approximately 1600 subjects from 143 families. The goal of the project was to identify any significant genetic markers of alcoholism (or surrogate phenotypic traits). |
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