Harvard School of Public Health
Department of Biostatistics

Environmental Statistics

Select Publications

Methodological Papers


Barr CD and Dominici F.   Cap and trade legislation for greenhouse gas emissions: Public health benefits from air pollution mitigation.   JAMA, 2010; 303:69-70

Barr CD and Shoenberg FP.   On the Voronoi estimator for the intensity of an inhomogeneous planar Poisson process.   Biometrika, 2010: In press.

Dominici F, Peng RD, Barr CD, Bell ML. Protecting human health from air pollution: Shifting from a single-pollutant to a multipollutant approach.   Epidemiol, 2010; 21:187-94.

Janes H, Dominici F, Zeger S.   On quantifying the magnitude of confounding.   Biostat, 2010; 11:572-82.

Li Y, Lin X, Muller P. Bayesian inference in semiparametric mixed modesl for longitudinal data.   Biometrics, 2010; 66:70-8.

Ramos-bonilla JP, Breysse PN, Dominici F, Geyh A, Tankersley CG.   Ambient air pollution alters heart rate regulation in aged mice.   Inhal Toxicol, 2010; 22:330-9.

Schoenberg FP, Barr CD, Seo JJ.   The distribution of Voronoi cells generated by Souther California earthquake epicenters.   Environmetrics, 2010; In press.

Wang L, Rotnitzy A, Lin X.   Nonparametric regression with missing outcomes using weighted kernel estimating equations.   JASA; 2010; In press.

Wu MC, Kraft P, Epstein MP, Taylor DM, Chanock SJ, Hunter DJ, Lin X.   Powerful SNP set analysis for case-control genome wide association studies.   Am J Human Genetics, 2010; doi:10.1016/j.ajhg.2010.05.002.


Katsouyanni K, Samet JM, Anderson HR, Atkinson R, Le Tertre A, Medina S, Samoli E, Touloumi G, Burnett RT, Krewski D, Ramsay T, Dominici F, Peng RD, Schwartz J, Zanobetti A, HEI Health Review Committee.   Air pollution and health: A European and North American approach (APHENA).   Res Rep Health Eff Inst. 2009; (142):5-90.

Li Y, Tang H, Lin X. Spatial linear mixed models with covariate measurement errors.   Statitica Sinica, 2009; 19:1077-1093.

Little R, Long Q, Lin X.   A comparison of methods for estimating the causal effect of a treatment in randomized clinical trials subject to noncompliance.   Biometrics, 2009; 65:640-9.

Pan W, Zeng D, Lin X. Estimation in semiparametric transition measurement error models for longitudinal data.   Biometrics, 2009; 65:728-36.

Wu MC, Zhang L, Wang Z, Christiani DC, Lin X.   Sparce linear discriminant analysis for simultaneous gene set/pathway significance test and gene selection.   Bioinformatics; 2009, 25:1145-1151.


Beard JR, Earnest A, Morgan G, Chan H, Summerhayes R, Dunn TM, Tomaska NA, Ryan L.  Socioeconomic disadvantage and acute coronary events - A spatiotemporal analysis.  Epidemiol, 2008; 19:485-492.

Chen JT, Coull BA, Waterman PD, Schwartz J, Krieger N.  Methodlogic implications of social inequalities for analyzying health disparities in large spatiotemporal data sets: An example using breast cancer incidence data (Northern and Southern California, 1988-2002).  Stat Med, 2008; 27(2):3957-3983.

Desantis SM, Houseman EA, Coull BA, Stemmer-Rachamimov A, Betensky RA.  A penalized latent class model for ordinal data.  Biostatistics, 2008; 9:249-262.

Harezlak J, Wu MC, Wang M, Schwartzman A, Christiani DC, Lin X. Biomarker discovery for arsenic exposure using functional data analysis and feature learning of mass spectrometry proteomic data.   J Proteome Res, 2008; 7:217-224.

Kwee L, Liu D, Lin X, Ghosh D, Epstein M.   A powerful and flexible multilocus association test for quantitative traits. Am J Hum Genet, 2008; 82:386-397.

Li Y, Prentice RL, Lin X.   Maximum likelihood estimation in semiparametric normal transformation models for bivariate survival data.   Biometrika, 2008; 95:947-960.

Liu D, Ghosh D, Lin X.   Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models.   BMC Bioinformatics, 2008; 9:292.

Nikolov MC, Coull BA, Catalano PJ, Goldeslki JJ.  Statistical methods to evaluate health effects associated with major source of air pollution: A case study of breathing patterns during exposure to concentrated Boston aerosol.  J Royal Stat Soc, Ser C, 2008; 57:357-378.

Paciorek CJ.   Bivariate binomial spatial modeling of Loa loa prevalence in tropical Africa - Comment.  JASA, 2008; 103:37-40.

Ryan L.  Combining data from multiple sources, with applications to environmental risk assessment.  Stat Med, 2008; 27:698-710.

Schipper M, Taylor J, Lin X.   Bayesian generalized monotonic functional mixed odels for the effects of radiation dose histograms on normal tissue complications. Stat Med, 2008; 26:4643-4656.

Schipper M, Taylor J, Lin X.   Generalized monotonic functional mixed models with application to modeling normal tissue complications. J Royal Stat Soc, C, 2008; 57:149-163.

ye W, Lin x, Taylor J. Semiparametric modeling of longitudinal measurements and time-to-event data - A two-stage regression calibration approach.   Biometrics, 2008; 64:1238-46.

Yu Z and Lin X.   Nonparametric regression using local kernel estimating equations for correlated failure time data.   Biometrika, 2008; 95:123-127.

Zeng D, Lin D, Lin X. Semiparametric linear transformation models with random effects for clustered time data.   Statistica Sinica, 2008; 18:355-377.


Adar SD, Gold DR, Coull BA, Schwartz J, Stone PH, Suh H.  Focused exposures to airborne traffic particles and heart rate variability in the elderly.  Epidem, 2007; 18:95-103.

Gryparis A, Coull BA, Schwartz J, Suh HH.   Semiparametric latent variable regression models for spatiotemporal modeling of mobile source particles in the greater Boston area.   J Royal Stat Soc, Series C, 2007; 56:183-209.

Harezlak J, Coull BA, Laird NM, Magari S, Christiani D.  Penalized solutions to functional regression problems.  Comp Stat & Data Anal, 2007; 51(10):4911-4925.

Harezlak J, Naumova E, Laird NM.   LongCriJP: A test for bump hunting in longitudinal data.  Stat Med, 2007; 26(6):1383-1397.

Harezlak J, Wang M, Christiani D, Lin X.   Quantitative quality-assessment techniques to compare frantionation and depletion methods in SELDI-TOF mass spectrometry experiements.   Bioinformatics, 2007; 23:2441-2448.

Houseman EA, Marsit C, Karagas M, Ryan LM.  Penalized item response theory models: Application to epigenetic alterations in bladder cancer.  Biometrics, 2007; 63(4):1269-1277.

Laden F, Puett R, Yanosky J, Paciorek C, Hart J, Schwartz J, Suh H, Camargo C, Speizer F.   Chronic exposure to particulate matter and cardiopulmonary disease.   Epidem, 2007; 17:S71.

Lin X.  Estimation using penalized quasilikelihood and quasi-pseudo-likelihood in Poisson mixed models.  Lifetime Data Anal, 2007; 13:533-544.

Liu D, Lin X, Ghosh D.  Semiparametric regression of multidimensional genetic pathway data: Least-squares kernel machines and linear mixed models.  Biometrics, 2007; 63-1079-1088.

Long Q, Little RJ, Lin X.   Causal inference in hybrid intervention trials involving treatment choice.   JASA, 2007; 103:474-484.

McCracken J, Schwartz J, Mittleman M, Ryan L, Artiga AD, Smith KR.   Biomass smoke exposure and acute lower respiratory infections among Guatemalan children.  Epidemiol, 2007; 18(5):S185.

Morara M, Ryan L, Houseman A, Strauss W.  Optimal design for epidemiological studies subject to designed missingness.  Lifetime Data Analy, 2007; 13:583-605.

Nikolov MC, Coull BA, Catalano PJ, Godleski JJ.   An informative Bayesian structural equations model to assess source-specific health effects of air pollution.   Biostatistics, 2007; 8(3):609-624.

Schwartz J, Maynard D, Gryparis A, Coull B, Suh H.   Both traffic particles and sulfate particles are associated with mortality risk in Boston.   Epidem, 2007; 17:S200.

Zhang D, Lin X, Zeng D.   Two-stage functional mixed modesl for evaluating the effect of logitudinal covariate profiles on a Scalar outcome.   Biometrics, 2007; 62:351-362.

Zanobetti A, Nearing B, Gold DR, Schwartz J, Coull B.  T-wave alternans and air pollution in patients with recent coronary events.   Epidem, 2007; 18:S148.


Brown KW, Sarnat JA, Coull BA, Suh HH, Spengler JD, Koutrakis P.  Relationships between personal, indoor, and outdoor levels of sulfate, elemental carbon, and PM2.5 for a cohort of individuals with cardiopulmonary disease.  Epidem, 2006; 17(6):S108-S109 Suppl. S.

Buck Louis GM, Dukic VM, Heagerty PJ, Louise TA, Lynch CD, Ryan LM, Schisterman EF, Trumble A, and the Pregnancy Modeling Working Group.  Statistical issues in modeling pregnancy outcome data.  Stat Methods Med Res, 2006; 15(2):103-126.

Coull BA, Houseman EA, Betensky RA.  A computationally tractable multivariate random effects model for clustered binary data.  Biometrika, 2006; 93(3):587-599.

Davis M, Smith T, Laden F, Hart J, Ryan L, Garshick E.   Structural equation modeling in exposure assessment.  Epidemiol, 2006; 17(6):S466-S466 Suppl. S.

Dubowsky SD, Gold DR, Schwartz J, Coull BA, Adamkiewicz G, Suh H.   The St. Louis bus study: A summary of methods and findings.   Epidem, 2006; 17(6): S55-S55 Suppl. S.

Harezlak J and Tu W.  Estimation of survival functions in interval and right censored data using STD behavioural diaries.  Stat Med, 2006; 25(23):4053-4064.

Houseman EA, Coull BA, Betensky RA.  Feature-specific constrained latent class analysis for genomic data.  Biometrics, 2006, 62:1062-1070.

Houseman EA, Coull BA, Ryan LM.  A functional-based distribution diagnostic for a linear model with correlated outcomes.  Biometrika, 2006; 93:911-926.

Houseman EA, Coull BA, Shine JP.  A nonstationary negative binomial time series with time-dependent covariates: Enterococcus counts in Boston Harbor.  JASA, 2006; 101:1365-1376.

Houseman EA and Milton DK.  Partial questionnaire designs, questionnaire non-response, and attributable fraction: Applications to adult onset asthma.  Stat Med, 2006; 25:1499-1519.

Li Y and Lin X.  Semiparametric normal transformation models for spatially correlated survival data.  JASA, 2006; 101:591-603.

Lin XH, Carroll RJ.  Semiparametric estimation in general repeated measures problems.  J Royal Stat Soc - Series B, 2006; 68:69-88, Part 1.

McCracken J, Diaz A, Castro E, Edwards R, Ryan L, Schwartz J, Chowdhury Z, Smith KR.   Biomass smoke exposure among Guatemalan infants participating in a randomized trial of chimney stoves.   Epidemiol, 2006; 17(6):S35-S36 Suppl. S.

Morales KH, Ibrahim JG, Chen CJ, Ryan LM.   Bayesian model averaging with applications to benchmark dose estimation for arsenic in drinking water.   JASA, 2006; 101(473):9-17.

Morris JS, Arroyo C, Coull BA, Ryan LM, Herrick R, Gortmaker SL.   Using wavelet-based functional mixed models to characterize population heterogeneity in accelerometer profiles: A case study.   JASA, 2006; 101:1352-1364.

Nan B, Lin X, Lisabeth LD, Harlow SD.  Piece-wise constant cross-ratio estimates or association of age at a marker event and age at menopause.  JASA, 2006; 101:65-77.

Paciorek CJ.   Misinformation in the conjugate prior for the linear model with implications for free-knot spline modelling.  Bayesian Analysis, 2006; 1:375-383.

Paciorek CJ and Schervish MJ.   Spatial modelling using a new class of nonstationary covariance functions.   Environmetrics, 2006; 17:483-506.

Pan W, Lin X, Zeng D.  Structural inference in transition measurement error models for longitudinal data.  Biometrics, 2006, 62:402-12.

Suglia SF, Ryan L, Bellinger D, Wright R.   The influence of the social and physical environment on child behavior.   Epidemiol, 2006; 17(6):S387-S387 Suppl. S.

Tchetgen EJ and Coull BA.  A diagnostic test for the mixing distribution in a generalised linear mixed model.  Biometrika, 2006; 93:1003-1010.

Yanosky J, Paciorek C, Schwartz J, Laden F, Suh H.  Assessing chronic exposure to particulate pollutants for the nurses' health study.   Epidem, 2006; 17:S485-S486.

Zhao Y, Staudenmayer J, Coull BA, Wand, MP.  General design Bayesian generalized linear mixed models.   Statistical Science, 2006; 21(1):35-51.


Bellamy SL, Li Y, Lin XH, Ryan LM.  Quantifying PQL bias in estimating cluster-level covariate effects in generalized linear mixed models for group-randomized trials.  Statistica Sinica, 2005; 15:1015-1032.

Burden S, Guha S, Morgan G, Ryan L, Sparks R, Young L.  Spatio-temporal analysis of acute admissions for ischemic heart disease in NSW, Australia.  Environ & Ecolog Stat, 2005; 12:427-448.

Chen JC, Christiani DC, Ryan LM.  Predicting exposure levels.  Epidemiol, 2005; 16:135.

Clougherty JE, Levy JI, Coull B, Spengler JD, Hynes HP.  Differential efficacy of environmental interventions for alleviating symptoms among asthmatic children in urban public housing.  Epidem, 2005; 16:S117-S118.

Coull BA.   Continuity correction.   In: Imrey PJ, Agresti, A eds. Encyclopedia of Biostatistics. New York: Wiley, 2005, DoI:10.1002/047001/1815.b2a10017.

Ganguli B, Staudenmayer J, Wand MP.  Additive models with predictors subject to measurement error.  Aust & NZ J Stat, 2005; 47:193-202.

Harezlak J, Ryan LM, Giedd JN, Lange N.   Individual and population penalized regression splines for accelerated longitudinal designs.  Biometrics, 2005; 61(4):1037-1048.

Hogan JW, Lin X, Herman B.   Mixtures of varying coefficient models for longitudinal data with discrete or continuous non-ignorable dropout.   Biometrics, 2005; 60:854-864.

Houseman EA.   A robust regression model for a first-order autoregressive time series with unequal spacing: Application to water monitoring.  J Royal Stat Soc - Series C. 2005; 54:769-780.

Kile M, Houseman EA, Rodrigues E, Quamruzzaman Q, Mahmuder R, Mahiuddin G, Su L, Christiani D.  Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water.  Cancer Epidemiol Biomarkers & Prev, 2005; 141:2419-2426.

Li Y and Ryan L.   Inference on survival data with covariate measurement error - an imputation approach.   Scandinavian J Stat, 2005; 33:169-190.

Lin X.  Biostaticial methods and research designs.  Encl Life Support Systems, 2005; in press.  Developed under the auspices of the UNESCO, Eolss Publishers, Oxford, UK.

Luttmann-Gibson H, Suh HH, Ebelt ST, Coull BA, Dockery DW, Stone PH, Gold DR.  Short-term effects of air pollution and heart rate variability in senior adults in Stubenville, OH.  Epidemiol, 2005; 16(5):S141-S142.

McCarty KM, Houseman A, Su L, Quamruzzaman Q, Rahman M, Mahiuddin G, Smith T, Ryan L, Christiani DC.  Drinking water exposure to arsenic polymorphisms in GSTT1, GSTM1 and GSTP1 and methylation capacity.  Epidemiol, 2005; 16(5):S113.

Morales KH and Ryan LM.   Benchmark dose estimation based on epidemiologic cohort data.   Environmetrics, 2005; 16:435-447.

Nan B, Lin X, Lisabeth LD, Harlow S.  A varying-coefficient Cox model for the effect of age at a marker event on age at menopause.  Biometrics, 2005; 61:576-583.

Pfeiffer RM, Ryan L, Litonjua A, Pee D.   A case-cohort design for assessing covariate effects in longitudinal studies.   Biometrics, 2005; 61(4):982-991.

Roy J and Lin X.  Missing covariates in longitudinal data with informative dropouts: Bias analysis and inference.  Biometrics, 2005; 61:837-846.

Sanchez BN, Budtz-Jorgensen E, Ryan LM, Hu H.  Structural equation models: A review with applications to environmental epidemiology. JASA, 2005; 100(472):1443-1455.

Thurston SW, Williams PL, Hauser R, Hu H, Hernandez-Avila M, Spiegelman D.   A comparison of regression calibration approaches for designs with internal validation data.   J Stat Planning & Inference, 2005; 131(1): 175-190.

Thurston SW, Williams PL, Hauser R, Spiegelman D.   A comparison of regression calibration approaches for designs with internal validation data.  J Stat Planning & Infer, 2005; 131:175-190.

Wang N, Carroll RJ, Lin XH.  Efficient semiparametric marginal estimation for longitudinal/clustered data.  JASA; 2005; 100:147-157.

Yu Z-F, Catalano PJ.   Quantitative risk assessment for multivariate continuous outcomes with application to neurotoxicology: The bivariate case.   Biometrics. 2005; 61:757-766.


Bellamy SL, Li Y, Ryan LM, Lipsitz S, Canner MJ, Wright R.  Analysis of clustered and interval censored data from a community-based study in asthma.  Stat Med, 2004; 23:3607-3621.

Carroll RJ, Hall P, Apanasovich TV, Lin X.&nbps; Histospline method in nonparametric regression models with application to longitudinal/clustered data.  Stat Sinica, 2004; 14:649-674.

Coull BA and Staudenmayer J.   Self-modeling regression for multivariate curve data.  Statistica Sinca, 2004; 14(3):695-711.

Dominici F, Zanobetti A, Zeger SL, Schwartz J, Samet JM.   Hierarchial bivariate time-series models: A combined analysis of the effects of particulate matter on morbidity and mortality.  Biostatistics. 2004; 5:341-360.

Elashoff M and Ryan L.  An EM algorithm for estimating equations.  J Computational & Graphical Stat, 2004; 13:48-65.

Faes C, Geys A, Aerts M, Molenberghs G, Catalano P.   Modeling combined continuous and ordinal outcomes in a clustered setting.   J Agricult Bio & Environ Stat. 2004; 9:515-530.

French JL and Wand MP.  Generalized additive models for cancer mapping with incomplete covariates.  Biostatistics, 2004; 5:177-191.

Ganguli B and Wand MP.  Feature significance in geostatistics.  J Computational & Graphical Stat, 2004; 13:954-973.

Han KE, Catalano PJ, Senchaudhuri P, Mehta C.   Exact analysis of dose-response for multiple correlated binary outcomes.  Biometrics 2004; 60:216-224.

Houseman EA, Ryan LM, Coull BA.  Cholesky residuals for assessing normal errors in a linear model with correlated outcomes.  JASA, 2004; 99:383-394.

Li L, Lin X, Brown MB, Gupta S, Lee KH.   A population pharmacokinetic model with time-dependent covariates measured with error.  Biometrics, 2004; 60:451-460.

Li Y and Ryan L.  Survival analysis with heterogeneous covariate measurement error.  JASA, 2004; 99:724-735.

Lin X, Wang N, Welsh A, Carroll RJ.  Equivalent kernels of smoothing splines in nonparametric regression for clustered data.  Biometrika, 2004; 91:177-193.

Linton OB, Mammen E, Lin X, Carrol RJ.  Accounting for correlation in marginal longitudinal nonparametric regression.  Proceedings of the Second Seattle Symposium in Biostatistics: Analysis of Correlated Data, D. Lin and P. Heagerty (Editors), 2004; 23-34.

Ngo L and Wand MP.  Smoothing with mixed model software.  J Stat Software, 2004; 9:1-56.

Ryan L, Huang W, Thurston SW, Kelsey KT, Wiencke JK, Christiani DC.  On the use of biomarkers for environmental health research.  Stat Methods Med Res, 2004; 13:207-225.

Wager CG, Coull BA, Lange N.   Modelling spatial intensity for replicated inhomogeneous point patterns in brain imaging.   J Royal Stat Soc, Series B, 2004; 66, 429-446.

Whitney JM and Ngo L.  Bayesian model averaging using the SAS software.  Technical Proceedings, Stat & Data Anal, SUGI 29, SAS Institute, Cary, NC. 2004.


Coull BA and Agresti A.  A class of generalized log-linear models with random effects.  Stat Model, 2003; 3:251-271.

Coull BA, Mezzetti M, Ryan LM.  A Bayesian hierarchical model for risk assessment of methylmercury.  J Agric Biol & Environ Stat, 2003; 8:253-270.

Epstein M, Lin X, Boehnke M.  A tobit variance-component method for linkage analysis of trunctated trait data.  Am J Human Genetics, 2003; 72:611-620.

Hamlett A, Ryan L, Serrano-Trepalacios P, Wolfinger R.  Mixed models for assessing correlation in the presence of replication.  J Air & Waste Management, 2003; 53:1-9.

Kammann EE and Wand MP.  Geoadditive models.  J Royal Stat Soc C, App Statistics, 2003; 52:1-18, Part 1.

Li Y and Lin X.  Functional inference in frailty measurement error models for clustered survival data using the SIMEX approach.  JASA, 2003; 98(461):191-204.

Li Y and Lin X.  Testing random effects in uncensored/censored clustered data with categorical responses.  Biometrics, 2003; 59(1)-25-35.

Li Y, Ryan L, Bellamy S, Satten G.  Inference on clustered surv-ival data using imputed frailties.  J Compu & Graphical Stat, 2003; 12(3):640-662.

Mezzetti M, Ibrahim JG, Bois F, Ryan LM, Ngo L, Smith TJ.  A Bayesian compartmental model for the evaluation of 1,3-Butadiene metabolism.  App Statistics, 2003; 52:291-305.

Rabbee N, Coull BA, Mehta CR, Patel N, Senchaudhuri P. Power and sample size for ordered categorical data. Stat Methods Med Res, 2003; 12(1):73-84.

Roy J, Lin X, Ryan L.  Scaled marginal models for multiple continuous outcomes.&nbps; Biostatistics, 2003; 4:371-384.

Schwartz J and Coull BA.  Control of confounding in the presence of measurement error in hierarchical models.  Biostatistics, 2003; 4:539-553.

Thurston SW, Spiegelman D, Ruppert D. Equivalence of regression calibration methods in main study/external validation study designs. J Stat Plan Infer, 2003; 113(2):527-539.

Tsimikas JV, Bosch R, Coull BA, El Barmi H. Profile-likelihood inference for highly accurate diagnostic tests. Biometrics, 2003; 58(4):946-956.

Wand MP.  Smoothing and mixed models.  Computational Stat, 2003; 18:223-249.

Zhang D and Lin X.  Hypothesis testing in semiparametric additive mixed models.  Biostatistics, 2003; 4:57-74.

Zhou W, Liu G, Miller DP, Thurston SW, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC. Polymorphisms in the DNA repair genes XRCCI and ERCC2, smoking & lung cancer risk. Cancer Epidemiology Biomarkers & Prevention, 2003; 12(4):359-365.


Aerts M, Claeskens G, Wand MP.  Some theory for penalized spline generalized additive models.  Special issue of J Statistical Planning & Inference in honor of the 80th Birthday of C.R. Rao, 2002; 103:455-470.

Agresti A and Coull BA.  The analysis of contingency tables under inequality constraints.  J Stat Plan & Infer, 2002; 107:45-73.

Betensky RA, Lindsey JC, Ryan LM, Wand MP.  A local likelihood hazards model for interval censored data.  Stat Med, 2002; 21:263-275.

Brand KP, Catalano PJ, Hammitt JK, Rhomberg L, Evans JS.  Limitations to empirical extrapolation studies: the case of BMD ratios.  Risk Analysis; 2002; 21:625-640.

Cai T, Hyndman RJ, Wand MP.  Mixed model-based hazard estimation.  J Computational & Graphical Stat, 2002; 11:784-798.

Coull BA, Holmes LB.  Environmental teratogenesis.  Encyclopedia of Environmetrics, John Wiley and Sons, England, 2002; 4:2174-276.

Coull BA, Ryan, LM.  Biological assay.  Encyclopedia of Environmetrics, John Wiley and Sons, England, 2002; 1:189-192.

Coull BA, Schwartz J.  Respiratory epidemiology.  Encyclopedia of Environmetrics, John Wiley and Sons, England, 2002; 3:1785-1788.

Coull BA, Wellenius GA.  Cardiac toxicology.  Encyclopedia of Environmetrics, John Wiley and Sons, England, 2002; 1:271-2772.

Epstein M, Lin X, Boehnke M.  Ascertainment-adjusted parameter estimates revisited.  Amer J Human Genet, 2002; 70:886-895.

Geys H, Molenberghs G, and Williams PL.  Analysis of toxicology data with covariates subject to each observation.  J Agric Biol & Environ Stat, 2002; 7:1-15.

Gray R and Li Yi.  Optimal weight functions for marginal proportional hazards analysis of clustered failure time data.  Lifetime Data Analysis, 2002; 8:4-19.

Houseman EA, Ryan L, Levy J, Spengler J.  Autocorrelation in real-time continuous monitoring of microenvironments.  App Stat, 2002; 29(6):855-872.

Li Y, Betensky R, Louis D, Cairncross J.  The use of frailty hazard models for unrecognized heterogeneity that interacts with treatment considerations of efficiency and power.  Biometrics, 2002; 58:232-236.

Li Y and Ryan L.  Modeling spatial survival data using semi-parametric frailty models.  Biometrics, 2002; 58(2):287-297.

Roy J and Lin X.  Analysis of mulitvariate longitudinal outcomes with non-ignorable dropouts and missing covariates: Changes in methadone treatment practices.  JASA, 2002; 97:40-52.

Spiegelman D, Ryan L, Piergorsch W.  Relative risk.  Encyclopedia of Environmetrics, 2002; 3:1743-1744.

Spiegelman D, Ryan L, Piergorsch W.  Validation studies.  Encyclopedia of Environmetrics, 2002; 4:2311-2313.

Thurston SW.  Biomarkers.  Ell-Shaarawi, A.H. Piegorsch, W.W., editors, Encyclopedia of Environmentrics. John Wiley and Sons, England, 2002; 1:194-196.

Thurston SW.  DNA adducts.  Ell-Shaarawi, A.H. Piegorsch, W.W., editors, Encyclopedia of Environmentrics. John Wiley and Sons, England, 2002; 1:561-562.

Thurston SW, Eisen EA, Schwartz J. Smoothing in survival models: an application to workers exposed to metalworking fluids. Epidemiology, 2002; 13:685-92.

Wand MP. Vector differential calculus in statistics.  Amer Statistician, 2002; 56:55-62.

Wand MP and Schwartz J.  Smoothing in environmental epidemiology.  Encyclopedia of Environmetrics, 2002; 4:2020-2023.

Weller E and Long N.  Statistical aspects of dose-rate (CxT) studies.  Encyclopedia of Environmentrics, 2002; 1:565-566.

Weller E, Ryan LM, Dockery D.  Statistical issues in inhalation toxicology.  Handbook of Statistics. editors P.K. Sen, C.R., Rao, 2002; 18:423-440.

Welsh AH, Lin X, Carroll RJ.  Marginal longitudinal nonparametric regression: Locality and efficiency of spline and kernel methods. JASA, 2002; 97:482-493.

Williams PL.  Reproductive toxicology.  Encyclopedia of Environmetrics, Wiley: New York, 2002.

Williams PL.  Quantitative structure-activity relationships (QSAR).  Encyclopedia of Environmetrics, Wiley: New York, 2002.


Betensky RA and Williams PL.  A comparison of models for clustered binary outcomes: analysis of a designed immunology experiment.  App Statistics, 2001; 50:43-61.

Brand KP, Catalano PJ, Hammitt JK, Rhomberg L, Evans JS.  The informativeness of benchmark dose ratios and the influence of dose selection.  Risk Analysis, 2001; 21(4):625-640.

Coull BA, Schwartz J, Wand MP.  Respiratory health and air pollution: additive mixed model analyses.  Biostatistics, 2001; 2:337-349.

Coull BA, Hobert JP, Ryan L, Holmes LB.  Crossed random effect models for multiple outcomes in a study of teratogenesis.  J Amer Stat Assoc, 2001; 96:1194.1204.

Coull BA, Ruppert D, Wand MP.  Simple incorporation of interactions into additive models.  Biometrics, 2001; 57:539-545.

French J and Williams PL.  Characterizing dose-response relationships in multiple cancer bioassays.  Risk Analysis, 2001; 21:91-102.

Geys H, Regan MM, Catalano PJ, Molenberghs G.  Two latent variable risk assessment approaches for mixed continuous and discrete outcomes from developmental toxicity data.  J Agricul Biol & Environ Stat, 2001; 6(3):340-355.

Lin X and Carroll RJ.  Discussion of ''Semiparametric and nonparametric analysis of longitudinal data,'' by D. Y. Lin and Z. Ying.  JASA, 2001; 96:114-115.

Lin X and Carroll RJ.  Semiparametric regression for clustered data.  Biometrika, 2001; 88:1179-1868.

Lin X and Carroll RJ.  Semiparametric regression for clustered data using generalized estimating equations.  Biometrika, 2001; 96:1045-1056.

Mammen E, Marron JS, Turlach BA, Wand MP.  A general framework for constrained smoothing.  Stat Sci, 2001; 16:232-248.

Parise H, Dinse GE, Ryan LM.  Flexible estimates of tumor incidence for intermediately lethal tumors in a typical long term animal bioassay.  J Royal Stat Soc, Series C- App Stat, 2001; 50:171-185.

Parise H, Wand M, Ruppert D, Ryan L.  Incorporation of historical controls using semiparametric mixed models.  J Royal Stat Soc, Series C- App Stat, 2001; 50:31-42r.

Rockhill B, Spiegelman D, Byrne C, Hunter DJ, Colditz GA.  Validation of the Gail etal. model of breast cancer risk prediction and implications for chemoprevention.  J NCI, 2001; 93-358-366.

Spiegelman D, Carroll RJ, Kipnis V.  Efficient regression calibration for logistic regression in main study/internal validation study designs.  Stat Med, 2001; 29:139-160.


Bernardo MVP, Lipsitz SR, Harrington DP, Catalano PJ.  Sample size calculations for failure time random variables in non-randomized studies.  Statistician, 2000; 49(1):31-40.

Coull B, Catalano PJ, Godleski J.  Semiparametric analyses of cross-over data with repeated measures.  J Agricul Biol & Environ Stat, 2000; 5(4):417-429.

Coull BA, Mezzetti M, Ryan LM.  Comment on "Combining evidence on air pollution and daily mortality from the 20 largest US cities: a hierarchical modelling strategy" by Francesca Dominici, Jonathan M. Samer, and Scott L. Zeger.  J Royal Stat Soc, Series A, 2000; 163:293.

Declerck L, Molenberghs G, Ryan LM. Litter based methods in developmental toxicity risk assessment. Environ & Ecol Stat, 2000; 7:57-76.

Hoppin JA, Williams PL, Ryan PB.  A conceptual framework for the interpretation of biological markers for environmental exposure assessment.  Human & Ecol Risk Assess, 2000; 6:711-725.

Ibrahim JG, Chen MH, Ryan LM.  Bayesian variable selection for time series count data.  Statistica Sinica, 2000; 10(3):971-987.

Li Y and Lin X.  Covariate measurement errors in frailty models for clustered survival.  Biometrika, 2000; 4:849-66.

Regan MM, Catalano PJ.  Regression modesl for mixed discrete and continuous outcomes with clustering.   Risk Analysis, 2000; 20(3):363-376.

Roy J and Lin X.  Latent variable models for longitudinal data with multiple continuous outcomes.  Biometrica, 2000; 56:1047-1054.

Schwartz J and Zanobetti A. Using meta-smoothing to estimate dose-response trends across multiple studies, with application to air pollution and daily death. Epidemiology, 2000; 11:666-672.

Spiegelman D, Rosner B, Logan R.  Estimation and inference for binary data with covariate measurement error and misclassification for main study/validation study designs.  J Amer Stat Assoc, 2000; 95:51-61.

Thürigen D, Spiegelman D, Heuer C, Blettner M, Brenner H.  Measurement error correction using validation data - a review of methods and their applicability in case-control studies.  Stat Methods in Med Res. 2000; 9:447-474.

Thurston SW, Wand MP, Wiencke JK. Negative binomial additive models. Biometrics, 2000; 56:139-144.

Wand MP.   A comparison of regression spline smoothing procedures.  Computational Stat, 2000; 15:443-462.

Weller E, Ryan L, Dockery D.  Statistical issues in inhalation toxicology.  Handbook of Statistics, eds., PK Sen and CR Rao,  2000; 18:423-440.

Zanobetti A, Wand MP, Schwartz J, Ryan LM.  Generalized additive distributed lag models. Biostatistics, 2000; 1:279-292.


Betensky RA, Lindsey JC, Ryan LM, Wand MP.  Local EM estimation of the hazard function for interval censored data.  Biometrics, 1999; 55:2338-245.

Brumback BA, Holmes LB, Ryan LM. Adverse effects of chorionic villus sampling: a meta-analysis. Stat Med, 1999; 18:2163-2175.

Geys H, Molenberghs G, Ryan LM.  Psuedolikelihood modeling of multivariate outcomes in developing toxicology.  J Amer Stat Assoc, 1999; 94:734-745.

Gijbels I, Pope A, Wand MP.  Automatic forecasting via exponential smoothing: asymptotic properties.  J Royal Stat Soc, Series B, 1999; 61:39-50.

Holcroft C, Spiegelman D.  Design of validation studies for estimating the odds ratio of exposure-disease relationships when exposure is misclassified.  Biometrics, 1999; 55:1193-1201.

Horton NJ, Bebchuk JD, Jones CL, Lipsitz SR, Catalano PJ, Zahner GEP, Fitzmaurice GM.  Goodness of fit for GEE: An example with mental health service utilization.  Stat Med, 1999; 18-213-222.

Hu FB, Stampfer MJ, Rimm E, Ascherio A, Rosner BA, Spiegelman D, Willett WC.  Dietary fat and coronary heart disease: a comparison of approaches to adjusting for total energy intake and modeling repeated dietary measurements.  Amer J Epidemiology, 1999; 149:531-540.

Morrissey MJ, Spiegelman D.  Matrix methods for estimating odds ratio with misclassified exposure data: extensions and comparisons.  Biometrics, 1999; 55:338-344.

Opsomer JD, Ruppert D, Wand MP.  Kriging with nonparametric variance function estimation.  Biometrics, 1999; 55:704-710.

Regan MM and Catalano PJ.  Bivariate dose-response modeling and risk estimation in developing toxicology.   Biological & Environ Stat, 1999; 4:217-237.

Regan MM, Catalano PJ.  Likelihood models for clustered binary and continuous outcomes: application to development toxicology.  Biometrics, 1999; 55:760-768.

Ryan LM, Molenberghs G.  Statistical methods for developmental toxicity: analysis of clustered multivariate binary data.  New York Academy of Sciences, 1999; 985:196-211.

Takkouche B, Cardarso-Suárez C, Spiegelman D.  An evaluation of old and new tests for heterogeneity in meta-analysis for epidemiologic research.  Amer J Epidemiology, 1999; 150:206-215.

Wand MP.  On the optimal amount of smoothing in penalized spline regression.  Biometrika, 1999; 86:936-940.

Wand MP.  A central limit theorem for local polynomial backfitting estimators.  J of Multivariate Analysis, 1999; 70:57-65.


Augustyns I and Wand MP.  Bandwith selection for local polynomial smoothing of multinominal data.  Computational Stat, 1998; 13:447-462.

Gaylor D, Ryan L, Krewski D, Zhu Y.  Procedures for calculating benchmark doses for health risk assessment.  Regulatory Toxicology & Pharmacology, 1998; 28:150-164.

Ibrahim JG, Ryan LM, Chen MH.  Use of historical controls to adjust for covariates in trend tests for binary data.  J Amer Stat Assoc, 1998; 93:1282-1293.

Spiegelman D.  Validation Studies.  Encyclopedia of Biostatistics, Colton T & Armitage P, eds. Sussex, England: Wiley, 1998; 4694-4700.

Spiegelman D.  Reliability Studies.  Encyclopedia of Biostatistics, Colton T & Armitage P, eds. Sussex, England: Wiley, 1998; 3771-3775.

Spiegelman D, Valanis B.  Correcting for bias in relative risk estimates due to exposure measurement error: a case study of occupational exposure to antineoplastics in pharmacists.  J Amer Public Health Assoc, 1998; 88:406-412.

Wand MP.  Finite sample performance of deconvolving density estimators.  Stat & Probability Letters, 1998; 37:131-139.

Weller EA and Ryan LM.  Testing for trend with count data.  Biometrics, 1998; 54:762-773.


Baird SJS, Catalano PJ, Ryan LM, Evans JS.  Evaluation of effect profiles: functional observational battery outcomes.  Fundamental & Applied Toxicol, 1997; 40:37-51.

Carroll RJ, Fan J, Gijbels I, Wand MP.  Generalized partially linear single-index models.  J Amer Stat Assoc, 1997; 92:477-489.

Catalano PJ. Bivariate modeling of clustered continuous and ordered categorical outcomes.   Stat Med, 1997; 16:883-900.

Demidenko E, Spiegelman D.  A paradox: more measurement error can lead to more efficient estimates.  Comm Stat - Theory & Methods, 1997; 26-1649-1675.

Foppa I, Spiegelman D.  Power and sample size calculations for case-control studies of gene-environment interactions with a polytomous exposure variable.  Amer J Epidemiology, 1997; 146:596-604.

Geys H, Molenberghs G, Ryan LM.  Psuedo-likelihood inference for clustered binary data.  Comm Stat: Theory & Methods, 1997; 26-2743-2767.

Hyndman RJ, Wand MP.  Nonparametric autocovariance function estimation.  Australian J Stat, 1997; 39:313-324.

Legler JM, Ryan LM.  Latent variable models for teratogenesis using multiple binary outcomes.  J Amer Stat Assoc, 1997; 92-13-20.

Ruppert D, Wand MP, Holst U, Hossjer O.  Local polynomial variance function estimation.  Technometrics, 1997; 39:262-273.

Spiegelman D, Casella M.  Fully parametric and semi-parametric regression models for common events with covariate measurement error, in main study/validation study designs.  Biometrics, 1997; 53-395-409.

Wand MP.  Data-based choice of histogram bin width.  Amer Stat, 1997; 51:59-64.

Wand MP and Gutierrez RO.  Exact risk approaches to smoothing parameter selection.  J Nonparametric Stat, 1997; 8:337-354.

Weller EA, Ryan LM, Spiegelman D, Smith T.  Statistical issues in assessing human population exposures.  Chemometrics, 1997; 37:189-195.

Williams PL.  Trend tests for counts and proportions.  Armitage P. and Colton T., eds.  Encyclopedia of Biostatistics, Section 10: Categorical Data Analysis, 1997.

Collaborative Papers


Brown KW, Sarnat JA, Suh HH, Coull BA, Spengler JD, Koutrakis P.  Ambient site, home outdoor and home indoor particulate concentrations as proxies of personal exposures.  J Environ Monitor, 2008; 10(9):1041-1051.

Chuang KJ, Coull BA, Zanobetti A, Suh H, Schwartz J, Stone PH, Litonjua A, Speizer FE, Gold DR.  Particulate air pollution as a risk factor for ST-segment depression in patients with coronary artery disease.  Circulation, 2008; 118(13):1314-1320.

Clark C, Ryan L, Kawachi I, Canner MJ, Berkman L, Wright RJ.  Witnessing community violence in residential neighborhoods: A mental health hazard for urban women.  J Urban Health, 2008; 85:22-38

Heist R, Zhai R, Liu G, Zhou W, Lin X, Su L, Asomaning K, Lynch T, Wain J, Chirstiani D.   VEGF polymorphism and survival in early stage non-small cell lung cancer.   J Clin Oncol, 2008; 26:856-862.

Nan B and Lin X.  Analysis of case-control age-at-onset data using a modified case-cohort method.  Biometrical J, 2008; 50:311-320.

Phipatanakul W, Celedon JC, Hoffman EB, Abdulkerim H, Ryan LM, Gold DR.  Mouse allergen exposure, wheeze and atopy in the first seven years of life.  Allergy, 2008: 63(11):1512-1518.

Sanda MG, Dunn RL, Michalski J, Sandler HM, Northouse L, Hembroff L Lin X, Greenfield T, Litwin MS, Saigal CS, Mahadevan A, Klein E, Kibel A, Pisters L, Kuban D, Kaplan I, Ciezki J, Shah N, Wei JT.   HRQOL and satisfaction with cancer treatment outcome from the perspective of early state cance patients and their spouse/partners.   NE J Med, 2008; 358:12:1250-1261.

Schwartz J, Coull B, Laden F, Ryan L.  The effect of dose and timing on the association between airborne particles and survival.  Environ Health Perspec, 2008; 116:64-69.

Suglia SF, Ryan L, Laden F, Dockery DW, Wright RJ.  Violence exposure, a chronic psychosocial stressor, and childhood lung function.  Psychosom Med, 2008; 70:160-169

Surkan PJ, Kawachi I, Ryan LM, Berkman LF, Vieira C, Peterson KE.  Maternal depressive symptoms, parenting self-efficacy, and child growth.  Am J Pub Health, 2008; 98-125:132.


Adar SD, Adamkiewicz G, Gold DR, Schwartz J, Coull BA, Suh H.  Ambient and microenvironmental particles and exhaled nitric oxide before and after a group bus trip.  Environ Health Perspec, 2007; 115(4):507-512.

Axelrad DA, Bellinger DC, Ryan LM, Woodruff TJ.  Dose response relationship of prenatal mercury exposure and IQ: An integrative analysis of epidemilogic data.  Env Health Perspec, 2007; 115(4):609-615.

Bateson TF, Coull BA, Hubbell B, Ito K, Jerrett M, Lumley T, Thomas D, Vedal S, Ross M.  Panel discussion review: session three - issues involved in interpretation of epidemiologic analyses - statistical modeling.  J Exposure Sci & Environ Epidemiol, 2007; 17:S90-S96.

Burns JS, Dockery DW, Neas LM, Schwartz J, Coull BA, Raizenne M, Speizer FE.  Low dietary nutrient intakes and respiratory health in adolescents.  Chest, 2007; 132:238-45.

Celedon JC, Milton DK, Ramsey CD, Litonjua AA, Ryan L, Platts-Mills TAE, Gold DR.  Exposure to dust mite allergen and endotoxin in early life and asthma and atophy in childhood.  J Allergy & Clin Immunol, 2007; 120(1):144-149.

Clark DE, Ryan LM, Lucal FL.&nbps; A multi-state piecewise exponential model of hospital outcomes after injury.  J Applied Stat, 2007; 34:1225-1239.

Dubowsky SD, Gold DR, Coull BA, Schwartz J, Stone PH, Suh H.  The effects of focused exposures to fresh traffic-related particles on heart rate variability in the elderly.  Epidemiol, 2007; 18:95-103.

Gryparis A, Coull BA, Schwartz J.  Controlling for confounding in the presence of measurement error in hierarchical models: a Bayesian approach.  J Exposure Sci & Environ Epidemiol, 2007; 17:S20-S28.

Hauser R, Meeker JD, Singh NP, Silva MJ, Ryan L, Duty S, Calafat AM.  DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites.   Hum Reprod, 2007; 22(3):688-695.

Ho SL, Li Y, Lin X, Lo EWC, Cheng KWE, Wong KF.  Calculations of eddy current, fluid, and thermal fields in an air insulated bus duct system.  IEEE Transcact Magnetics, 2007; 43(4):1433-1436.

Imrich A, Ning Y, Lawrence J, Coull B, Gitin E, Knutson M, Kobzik L.  Alveolar macrophage cytokine response to air pollution particles: Oxidant mechanisms.  Toxicol Appl Pharmacol, 2007; 218:356-64.

Maynard D, Coull BA, Gryparis A, Schwartz J.  Mortality risk associated with short-term exposure to traffic particles and sulfates.  Environ Health Perspect, 2007; 115:751-755.

McCarty KM, Chen YC, Quamruzzaman Q, Rahman M, Mahiuddin G, Hsueh YM, Su L, Smith T, Ryan L, Christiani DC.  Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions. Env Health Perspec, 2007; 115(3):341-345.

McCarty KM, Ryan L, Houseman EA, Williams PL, Miller DP, Quamruzzaman Q, Rahman M, Mahiuddin G, Smith T, Gonzalez E, Su L, Christiani DC.   A case-control study of GSTpolymorphisms and arsenic related skin lesions.  Env Health, 2007; 6:5.

McCarty KM, Smith TJ, Zhou W, Gonzalez E, Quamruzzaman Q, Mahjuddin G, Ryan L, Su L, Christiani DC.   Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn, and arsenic-related skin lesions.  Carcinogenesis, 2007; 28:1697-1702

Missmer SA, Pearson KR, Ryan LM, Meeker JD, Cramer DW, Hauser R.  Methodologic issues and statistical approaches to the analysis of multiple cycle data from couples undergoing in vitro fertization (IVF).  Fertility & Sterility, 2007; 88:S123, Suppl. 1.

Peters JL, Levy JI, Muilenberg ML, Coull BA, Spengler JD.  Efficacy of integrated pest management in reducing cockroach allergen concentrations in urban public housing.  J Asthma, 2007; 44:455-60.

Ramsey CD, Gold DR, Litonjua AA, Sredl DL, Ryan L, Celedon JC.  Respiratory illnesses in early life and asthma and atopy in childhood.   J Allergy & Clinical Immunol, 2007; 119(1):150-156.

Surkan PJ, Ryan LM, Vieira LMC, Berkman LF, Petersen KE.  Maternal social and psychological conditions and physical growth in low-income children in Piaui, Northeast Brazil.   Soc Sci & Med, 2007; 64:375-388.

Schwartz J, Sarnat JA, Coull BA, Wilson WE.  Effects of exposure measurement error on particle matter epidemiology: A simulation using data from a panel study in Baltimore, MD.  J Expo Sci Environ Epidemiol, 2007; Suppl 2:S2-10.

Tonne C, Melly S, Mittleman M, Coull BA, Goldberg R, Schwartz J.  A case-control analysis of exposure to traffic and acute myocardial infarction.  Environ Health Perspect, 2007; 115:53-57.

Wellenius GA, Yeh GY, Coull BA, Suh HH, Phillips RS, Mittleman MA.  Effects of ambient air pollution on functional status in patients with chronic congestive heart failure: A repeated-measures study.  Environ Health, 2007; 10:6-26.


Breton CV, Houseman EA, Kile ML, Quamruzzaman Q, Rahman M, Mahiuddin G, Christiani DC.   Gender-specific protective effect of hemoglobin on arsenic-induced skin lesions.   Cancer Epidemiol Biomarkers & Prev, 2006; 15(5):902-907.

Chen JT, Rehkoph DH, Waterman PD, Subramanian SV, Coull BA, Cohen B, Ostrem M, Krieger N.  Mapping and measuring social disparities in premature mortality: the impact of census tract poverty within and across Boston neighborhoods, 1999-2001.  J Urban Health, 2006; 83:1063-1084.

Choi AL, Levy JI, Dockery DW, Ryan LM, Tolbert PE, Altshul LM, Korrick SA.   Does living near a superfund site contribute to higher polychlorinated biphenyl (PCB) exposure?   Environ Health Perspec, 2006; 114(7):1092-1098.

Davis ME, Smith TJ, Laden F, Hart JE, Ryan LM, Garshick E.  Modeling particle exposure in US trucking terminals.  Environ Sci & Tech, 2006; 40(13):4226-4232.

Diez Roux AV, Auchincloss AH, Astor B, Barr G, Cushman M, Dvonch T, Jocobs DR, Kaufman J, Lin X, Samson P.   Recent exposure to particulate matter and C-reactive protein concentration in the multiethnic study of atherosclerosis.   Am J Epidemiol, 2006; 164:437-448.

Dubowsky SD, Suh HH, Schwartz J, Coull BA, Gold DR.  Diabetes, obesity and hpertension may enhance assoications between air pollution and markers of systemic inflammation.   Environ Health Perspect, 2006; 114(7):992-998.

Gold DR, Willwerth BM, Tantisira KG, Finn PW, Schaub B, Perkins DL, Tzianabos A, Ly NP, Schroeter C, Gibbons F, Campos H, Oken E, Gillman MW, Palmer LJ, Ryan LM, Weiss ST.  Association of cord blood fatty acids with lymphocyte proliferation IL-13, and IFN-gamma.  J Allergy & Clin Immunol; 2006; 117:931-938.

Li Y and Ryan L.   Inference on survival data with covariate measurement error - an imputation-based approach.   Scand J Stat, 2006; 33(2):169-190.

Louis GB, Dukic V, Heagerty PJ, Louis TA, Lynch DC, Ryan LM, Schisterman EF, Trumble A.   Analysis of repeated pregnancy outcomes.   Stat Methods Med Res, 2006; 15(2):103-126.

Luttmann-Gibson H, Coull BA, Dockery DW, Ebelt ST, Schwartz J, Stone PH, Suh HH, Gold DR.  Short-term effects of air pollution on heart rate variability in senior adults in Steubenville, OH.  J Occup & Environ Med, 2006; 48(8):780-788.

Krieger N, Chen JT, Waterman PD, Rehkopf DH, Yin RH, Coull BA.  Race/ethnicity and changing US socioeconomic gradients in breast cancer incidence: California and Massachusetts, 1978-2002 (United States).  Cancer Causes & Control, 2006; 17:217-226.

McCarty KM, Houseman EA, Quamruzzaman Q, Rahman M, Mahiuddin G, Smith T, Ryan L, Christiani DC.   The impact of diet and betel nut use on skin lesions associated with drinking-water arsenic in Pabna, Bangladesh.   Environ Health Perspec, 2006; 114(3):334-340.

Meeker JD, Ryan L, Barr DB, Hauser R.  Exposure to nonpersistent insecticides and male reproductive hormones.  Epidemiol, 2006; 17(1):61-58.

Park S-K, Schwartz J, Weisskoph M, Sparrow D, Vokonas PS, Wright RO, Coull BA, Hu H.  Low-level exposure, metabolic syndrome and heart rate variability: The VA Normative Aging Study.  Environ Health Perspect, 2006; 114(11):1718-1724.

Roux AVD, Auchincloss AH, Astor B, Barr G, Cushman M, Dvonch T, Jocobs DR, Kaufman J, Lin X, Samson P.  Recent exposure to particulate matter and C-reactive protein concentration in the multiethnic study of atherosclerosis.  Am J Epidemiol, 2006, 164:437-448.

Sama SR, Milton DK, Hunt PR, Houseman EA, Henneberger PK, Rosiello RA.   Case-by-case assessment of adult-onset asthma attributable to occupational exposures among members of a health maintenance organization.  J Occupational & Environ Med, 2006; 48:400-407.

Sarnat SE, Coull BA, Ruiz PA, Koutrakis P, Suh HH.  The Influences of ambient particle composition and size on particle infiltration in Los Angeles, CA, residences.  J Air & Waste Mgmt Assoc, 2006; 186-196.

Sarnat SE, Coull BA, Schwartz J, Gold DR, Suh HH.  Factors affecting the association between ambient concentrations and personal exposures to particles and gases.  Environ Health Perspect, 2006; 114:649-654.

Sarnat SE, Suh HH, Coull BA, Schwartz J, Stone PH, Gold DR.  Associations between cardiac arrhythmia and ambient particulate air pollution in a panel of senior adults in Steubenville, OH.  Occupat & Environ Med, 2006; 63:700-706.

Su L, Zhou W, Asomaning K, Lin X, Wain J, Lynch T, Liu G, Christiani D.  Genotypes and hyplotyes of matrix metalloproteinases and the risk of lung cancer.  Carcinogenisis, 2006; 27:1024-1029.

Wellenius GA, Coull BA, Batalha JRF, Diaz EA, Lawrence J, Godleski JJ.  Effects of ambient particles and carbon monoxide on supraventricular arrhythmias in a rat model of myocardial infarction.  Inhalation Toxicol, 2006; 18(14):1077-1082.


Abraham JH, Finn PW, Milton DK, Ryan LM, Perkins DL, Gold DR.  Infant home endotoxin is associated with reduced allergen-stimulated lymphocyte proliferation and IL-13 production in childhood.  J Allergy & Clin Immunol, 2005; 116:431-437.


Abraham JH, Gold DR, Dockery DW, Ryan L, Park J-H, Milton DK. Within-home versus between-home variability of house dust endotoxin in a birth cohort.  Env Health Perspect, 2005; 113:1516-1521.

Betensky RA, Houseman EA, Coull BA, Mikkelson T, Tahash L, Cairncross JG, Louise DN, Bogler O.  Analysis of 'medium throughput' quantitative LOH in anaplastic oligodendroglioma.  Neuro-oncol, 2005; 7:364-364.

Cabana MD, Slish KK, Nan B, Lin X, Clark N.  Asking the correct question to assess asthma symptoms.  Clinical Pediatrics, 2005; 44(4):319-325.

Chen C, Wang X, Wang L, Yang F, Tang G, Xing H, Ryan L, Lasley B, Overstreet JW, Stanford JB, Xu X.  Effect of environmentatl tobacco smoke on levels of urinary hormone markers.  Environ Health Perspec, 2005; 113(4):412-7.

Gold DR, Litonjua A, Zanobetti A, Coull BA, Schwartz J, MacCallum G, Verrier R, Nearing B, Canner MJ, Suh H, Stone PH.  Air pollution and ST-segment depression in elderly subjects.  Environ Health Perspec, 2005; 113:883-887.

Holmes LB, Coull BA, Dorfman J, Rosenberger PB.   Correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsants.   J Pediatrics, 2005; 146:118-122.

Krieger N, Chen JT, Coull BA, Selby JV.  Lifetime socioeconomic position and twins' health: An analysis of 308 pairs of United States women twins.  PLOS Med, 2005; 2:645-653.

Koutrakis P, Sax SN, Sarnat JA, Coull B, Demokritou P, Oyola P, Garcia J, Gramsch E.   Analysis of PM10, PM2.5, and PM2.5-10 concentrations in Santiago, Chile from 1989 to 2001.   J Air & Waste Manag Assoc, 2005; 55:342-351.

Krieger N, Chen JT, Coull BA, Selby JV.  Lifetime socioeconomic position and twin's health: An analysis of 308 pairs of United States women twins. PLOS Med, 2005; 2:645-653.

Le Tertre A, Schwartz J and Touloumi G on behalf of the Apheis group.   Empirical Bayes and adjusted estimates approach to estimating the relation of mortality to exposure of PM10.  Risk Analysis, 2005; 25:711-718.

Lewis TC, Robins TG, Dvonch JT, Yip FY, Mentz GB, Lin X, Parker EA, Keeler GJ, Israel BA, Gonzalez L, Hill Y.  Current levels of air pollution on Detroit are associated with changes in lung function among asthmatic children.  Environ Health Persp, 2005; 113:1068-1075.

Litonjua AA, Celedon JC, Hausmann J, Nikolov M, Sredl D, Ryan L, Platts-Mills TA, Weiss ST, Gold DR.  Variation in total and specific IgE: Effects of ethnicity and socioeconomic status.  J Allergy Clin Immunol, 2005; 115:751-7.

McCarty KM, Houseman EA, Quamruzzaman Q, Rahman M, Mahiuddin G, Smith T, Ryan L, Christiani D.  The impact of diet and betel nut use on skin lesions associated with drinking-water arsenic in Pabna, Bangladesh.  Environ Health Perspec, 2006; 114(3):334-340.

Sarnat JA, Brown KW, Schwartz J, Coull BA, Koutrakis P.  Ambient gas concentration and personal particulate matter exposures - Implications studying the health effects of particles.  Epidemiol, 2005; 16:385-395.

Stark PC, Celedon JC, Chew GL, Ryan LM, Burge HA, Muilenberg ML, Gold DR.  Fungal levels in the home and allergic rhinitis by 5 years of age.  Environ Health Persp, 2005; 113:1405-1409.

Zhou W, Liu G, Park S, Wang Z, Wain JC, Lynch TJ, Su L, Christiani DC.  Gene-smoking Interaction Associations for the ERCC1 polymorphisms in the risk of lung cancer.  Cancer Epidem Biomarkers & Prevention, 2005; 14:491-496.


Cabana MD, Slish KK, Lewis TC, Brown R, Nan B, Lin X, Clark N.  Parental management of asthma triggers within a child's environment.  J Allergy & Clinical Immunol, 2004; 114:352-357.

DeMeo DL, Zanobetti A, Litonjua AA, Coull BA, Schwartz J, Gold DR.   Ambient air pollution and oxygen saturation.   J Respiratory & Critical Care Med, 2004; 170:383-387.

Eisen EA, Agalliu I, Coull BA, Thurston SW, Kriebel D, Checkoway H.   Smoothing methods applied to occupational cohort studies: illustrated by penalized splines.   J Occupational & Environ Med, 2004; 61:854-860.

Gurubhagavatula S, Liu G, Park S, Zhou W, Su L, Wain JC, Lynch TJ, Neuberg DS, Christiani DC.  XPD and XRCC1 Genetic Polymorphisms Are Prognostic Factors in Advanced Non-Small-Cell Lung Cancer Patients Treated With Platinum Chemotherapy.  J Clinical Oncology, 22(13):2594-2601, 2004.

Hauser R, Meeker J, Park S, Calafat A.  Temporal Variability of Urinary Phthalate Metabolite Levels in Men of Reproductive Age.  Environmental Health Perspectives, 2004; 112(17): 1734-1740.

Kim JY, Mukherjee S, Ngo L, Christiani CD.  Urinary 8-hydroxy-2'- deoxyguanosne as a biomarker of oxidative DNA damage in workers exposed to fine particulates.  Environ Health Perspect, 2004; 112:666-671.

Lisabeth L, Harlow H, Gillespie B, Lin X, Sowers MF.  Staging reproductive aging: A compaison of proposed bleeding criteria for the menopausal transition.  Menopause, 2004; 11:186-197.

Lisabeth L, Harlow H, Lin X, Gillespie B, Sowers MF.  Sampling strategies for prospective studies of menstrual function.  Am J Epidemiol, 2004; 159:795-802.

Liu Y, Sarnat JA, Coull BA, Koutrakis P, Jacob DJ.   Validation of MISR aerosol optical thickness measurements using AERONET observations over the contiguous United States.   J Geophysical Res, 2004; 109:Art. No. D06205.

Liu G, Zhou W, Wang LI, Park S, Miller DP, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC.  MPO and SOD2 polymorphisms, gender, and the risk of non-small cell lung carcinoma.  Cancer Letters, 214(1):69-79, 2004

Liu G, Zhou W, Wang LI, Park S, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC.  The SOD2 Val/Val genotype enhances the risk of non-small cell lung carcinoma by p53 and XRCC1 polymorphisms.  Cancer, 2004; 101:2802-8.

McClean MD, Rinehart RD, Ngo L, Eisen EA, Herrick RF. Inhalation and dermal exposure among asphalt workers. Annals Occupational Hygiene, 2004; 48:663-671.

McClean MD, Rinehart RD, Ngo L, Eisen EA, Kelsey K, Wiencke J. Herrick RF. DNA adducts and polycyclic aromatic hydrocarbon exposure among asphalt paving workers.   Annals of Occupational Hygiene, 2004; 48:663-71.

McClean MD, Rinehart RD, Ngo L, Eisen EA, Kelsey K, Wiencke J. Herrick RF.  Urinary 1-Hydroxypyrene and polycyclic hydrocarbon exposure among asphalt paving workers.  Annals of Occupational Hygiene, 2004; 48(6):565-578.

Rojas-Bracho L, Suh HH, Catalano PJ, Koutrakis P.   Personal exposures to particles and their relationships with personal activities for chronic obstructive pulmonary disease patients living in Boston.   J Air & Waste Manage Assoc 2004; 54(2):207-217.

Schwartz J, Samet JM, Patz JA.   The effects of Temperature and Humidity on Hospital Admissions for Heart Disease.   Epidemiol, 2004 Nov;15(6):755-61.

Su L, Zhou W, Park S, Wain JC, Lynch TJ, Liu G, Christiani DC.  Matrix Metalloproteinase-1 Promoter Polymorphism and Lung Cancer Risk.  Cancer Epidem Biomarkers & Prevention, 2004; In press.

Teklehaimanot HD, Lipsitch M , Teklehaimanot A , Schwartz J.   Weather-based prediction of Plasmodium falciparummalaria in epidemic-prone regions of Ethiopia I. Patterns of lagged weather effects reflect biological mechanisms.  Malaria Journal, 2004: 3:41, doi:10.1186/1475-2875-3-41.

Teklahaimanot HD, Schwartz J, Teklahaimanot A, Lipsitch M.   Alert threshold algorithms for anticipating malaria epidemics. Emerging Infectious Disease,   2004; Jul;10(7):1220-6.

Vinturella AE, Burgess RM, Coull BA, Thompson KM, Shine JP.   Importance of black carbon in distribution and bioaccumulation models of polycyclic aromatic hydrocarbons in contaminated marine sediments.   Environ Toxicol & Chem, 2004; 23:2578-2586.

Vinturella AE, Burgess RM, Coull BA, Thompson KM, Shine JP.   Use of passive samplers to mimic uptake of polycyclic aromatic hydrocarbons by benthic polychaetes.   Environ Sci & Technol, 2004; 38:1154-1160.

Wellenius GA, Batalha JRF, Diaz EA, Lawrence J, Coull BA, Katz T, Verrier RL, Godleski JJ.  Cardiac effects of carbon monoxide and ambient particles in a rat model of myocardinal infarction.  Toxicological Sciences, 2004; 80:367-376.

Wright JM, Schwartz J, Dockery DW.  The effect of disinfection by-products and mutagenic activity on birth weight and gestational duration.  Environ Health Perspect, 2004; 112:920-925.

Zeka A, Schwartz J.   Estimating the independent effects of multiple pollutants in the presence of measurement error: An application of a measurement error resistant technique.   Environ Health Perspect, 2004; Dec;112(17):1686-90.

Zhou W, Gurubhagavatula S, Liu G, Park S, Neuberg DS, Wain JC, Lynch TJ, Su L, Christiani DC.  ERCC1 genetic polymorphisms as a predictor for overall survival in advanced non-small cell lung carcinoma patients treated With platinum-based chemotherapy.  Clinical Cancer Research, 2004; 10(15): 4939-4943.


Hamada K, Suzaki Y, Goldman A, Ning Y, Goldsmith C, Palecanda A, Coull BA, Hubeau C, Kobzik L.  Allergen-independent maternal transmission of asthma susceptibility.  J Immunol, 2003; 170:1683-1689.

Harvey EA, Coull BA, Holmes LB.   Anticonvulsant teratogenesis 5: Observer bias in a cohort study of the teratogenicity of anticonvulsant drugs.   Birth Defects Research: Clinical & Molecular Teratology, 2003; 67:452-456.

Lee MM, Sergeyev O, Williams P, Korrik S, Zeilert V, Revich B, Hauser R.  Physical growth and sexual maturation of boys in Chapaevsk, Russia.   J Pediatric Endocr Met, 2003; 16(2):169-178.

Levy JL, Bennett DH, Melly SJ, Spengler JD.  The influence of traffic patterns on particulate matter and polycyclic aromatic hydrocarbon concentrations in Roxbury, Massachustts.  J Exp Anal Environ Epidemiol, 2003; 13-364-371.

Levy JL, Wilson AM, Evans JS, Spengler JD.  Estimation of primary and secondary particulate matter intake fractions for power plants in Georgia.  Environ Sci Technol, 2003; 37:5528-5536.

Morrison AM, Couglin K, Shine JP, Coull BA, Rex A.  Receiver operating characteristic curve analysis of beach water quality indicator variables.  Appl Environ Microbiol, 2003; 69:6405-6411.

O'Neill MS, Jerrett M, Kawachi I, Levy JL, Gouveia N, Cohen AJ, Wilkinson P, Fletcher T, Cifuentes L, Schwartz J.  Health, wealth, and air pollution.  Environ Health Perspect, 2003; 111:1861-1870.

Orup IH, Keith DA, Coull BA, Holmes LB.   Craniofacial skeletal deviations following in utero exposure to the anticonvulsant phenytoin: monotherapy and polytherapy.   Orthodontics & Craniofacial Res, 2003; 6:2-19.

Savage ST, Lawrence T, Katz T, Stearns R, Coull BA, Godleski JJ.  Does the Harvard/Environmental Protection Agency ambient particle concentrator change the toxic potential of particles?  J Air & Waste Management Assoc, 2003; 53:1088-1097.

Shine JP, Trapp CJ, Coull BA.  Use of receiver operating characteristics (ROC) curves to evaluate sediment guidelines for metals. Environ Tox & Chem, 2003; 22:1642-1648.

Su L, Liu G, Zhou W, Xu LL, Miller DP, Park S, Lynch TJ, Wain JC, Christiani DC. No association between the p21 codon 31 Serg-Arg polymorphism and lung cancer risk. Cancer Epid Biomarkers & Prev, 2003; 12:174-175.

Wellenius GA, Coull BA, Godleski JJ, Koutrakis P, Okabe K, Savage ST, Lawrence JE, Murthy GG, Verrier RL.  Inhalation of concentrated ambient air particles exacerbates myocardial ischemia in conscious dogs.  Environ Health Perspect, 2003; 111:402-8.


Bainbridge KE, Sowers MF, Crutchfield M, Harlow SD, Lash RW, Lin X, Jannausch M.  A six-year natural history of bone loss among pre, peri and early postmenopausal women.  Am J Epidemiol, 2002; 156:410-417.

Batalha JRF, Saldiva PHN, Clarke RW, Coull BA, Stearns RC, Lawrence J, Krishna Murthy GG, Koutrakis P, Godleski JJ. Concentrated ambient air particles induce vasonconstriction of small pulmonary arteries in rats. Environ Health Perspec, 2002; 110(12):1191-1197.

Batalha JRF, Saldiva PHN, Clarke RW, Coull BA, Stearns RC, Lawrence J, Krishna Murthy GG, Koutrakis P, Godleski JJ.  Concentrated ambient air particles induce vasoconstriction of small pulmonary arteries in rats.  Environ Health Perspec, 2002; 110:191-197.

Bokhari A, Connolly S, Coull BA, Harvey EA, Holmes LB.   Effects on toes from prenatal exposure to anticonvulsants.   Teratology, 2002; 66:122-126.

Bokhari A, Coull BA, Holmes LB.   Effect of prenatal exposure to anticonvulsant drugs on dermal ridge patterns of fingers.   Teratology, 2002; 66:19-23.

Braga ALF, Zanobetti A, Schwartz J.   The effect of weather on respiratory and cardiovascular deaths in 12 US cities.   Environ Health Perspect, 2002; 110(9):859-863.

Celedon JC, Litonjua AA, Ryan L, Weiss ST, Gold DR.  Day care attendance, respiratory tract illness, wheezing, asthma, and total serum IgE level in early childhood.  Archives of Ped & Adoles Med, 2002; 156(3):241-245.

Chandlee J, Heathfield LT, Salganik M, Damokosh A, Radcliffe J.  Are we consistent in administering and scoring the Bayley Scales of Infant Development - II.  J Psychoeduc Assess, 2002; 20(2):183-200.

Cho SI, Goldman MB, Ryan LM, Chen C, Damokosh AI, Christiani DC, Lasley BL, O'Connor JF. Reliability of serial urine HCG as a biomarker to detect early pregnancy loss. Human Reproduction, 2002; 17(4):1060-1066.

Duty SM, Singh NP, Ryan L, Chen Z, Lewis C, Huang T, Hauser R.  Reliability of the comet assay in cryopreserved human sperm.  Human Reproduction, 2002; 5:1274-1280.

Godleski JJ, Clarke RW, Coull BA, Saldiva PHN, Jiang N-F, Lawrence J, Koutrakis P.   Composition of inhaled urban air particles determines acute pulmonary responses.   Annals of Occupational Hygiene, 2002; 46:419-424.

Goldsmith C, Ning Y, Qin G, Morgan B, Imrich A, Lawrence J, Murthy GG, Catalano P, Kobzik L.   Effect of combined ozone and air pollution particle exposure in mice.   Inhal Tox, 2002; 14:325-347.

Gurgueira SA, Lawrence J, Coull BA, Krishna Murthy GG, Gonzalez-Flecha B.  Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation.  Environ Health Perspec, 2002; 110(8):749-755.

Hauser R, Altshul L, Chen Z, Ryan L, Overstreet J, Schiff I, Christiani DC. Environmental organochlorines and semen quality: results of a pilot study. Environ Health Perspec, 2002; 110; 3:229-233.

Janssen NA, Schwartz J, Zanobetti A, Suh HH. Air conditioning and combustion related particles as modifiers of the effect of PM10 on hospital admissions for heart and lung diseases. Environ Health Perspec, 2002; 110:43-49.

Kimmel GL, Williams PL, Claggett TW, Kimmel CA.  Response-surface analysis of exposure-duration relationships: the effects of hyperthermia on embryonic development of the rat in vitro response-surface analysis.   Toxicology, 2002; 69(2):391-399.

Levy JL, Greco SL, Spengler JD.  The importance of population susceptiblity for air pollution risk assessment: A case study of power plants near Washington, D.C.  Environ Health Perspect, 2002; 110:1253-1260.

Levy JL and Spengler JD.  Modeling the benefits of power plant emission controls in Massachusetts.  J Air Waste Manage Assoc, 2002: 52:5-18.

Magari SR, Hauser R, Schwartz J, Williams PL, Smith TJ, Christiani DC.  Association of heart rate variability with occupational and environmental exposure to particulates.   Circulation, 2002; 104:986-991.

Magari SR, Schwartz J, Williams PL, Hauser R, Smith TJ, Christiani DC.  The association between personal measurements of environmental exposure to particulates and heart rate variability.  Epidemiology, 2002; 13(3):305-310.

Saldiva P, Clarke RW, Stearns R, Lawrence J, Koutrakis P, Hsu H, Tsuda A, Coull BA, Godleski JJ.  The actue inflammatory reaction induced by concentrated ambient particles is influenced by particle compostion.  J Respir & Crit Care Med, 2002; 165:1610-1617.

Sarnat JA, Long CM, Coull BA, Suh HH.  Using sulfur-related particles to estimate indoor particle and elemental concentration of outdoor origin.  Environ Sci & Tech, 2002; 36:5305-5314.

Schwartz J, Laden F, Zanobetti A.   The concentration-response relation between air pollution and daily deaths.   Environ Health Perspect. 2002; 110(10):1025-1029.

Wellenius GA, Saldiva PH, Batalha JRF, Krishna Murthy GG, Coull BA, Verrier RL, Godleski JJ.  Electrocardiographic changes during exposure to residual oil fly ash (ROFA) particles in a rat model of myocardial infarction.  Toxicol Sci, 2002; 66:327-335.

Zanobetti A, Schwartz J, Samoli E, Gryparis A, Touloumi G, Atkinson R., Le Tertre A, Bobros J, Celko M, Goren A, Forsberg B, Michelozzi P, Rabczenko D, Ruiz EA, Katsouyanni K. The temporal pattern of morality responses to air pollution: a multicity assessment of mortality displacement.  Epidemiol, 2002; 13:87-93.

Zhou W, Liu G, Miller DP, Thurston SW, Xu LL, Wain JC, Lynch TJ, Su L, Christiani DC. Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancer. Cancer Research, 2002; 62:1377-1381.

Zhou W, Liu G, Thurston SW, Xu LL, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC. Genetic polymorphisms of n-acetyltranferase-2 and microsomal epoxide hydrolase and cumulative cigarette smoking in lung cancer. Cancer Epidemiology Biomarkers & Prevention, 2002; 11:15-21.


Braga AL, Alfesio LF, Saldiva PHN, Paulo HN, Pereira LAA, Menezes JC, Joaquim JC, Conceicao Gleice MS, Lin CA, Zanobetti A, Schwartz J, Dockery DW.  Health effects of air pollution on children and adolescents in Sao Paulo, Brazil.  Pediatric Pulmonology, 2001; 31:106-113.

Braga AL, Zanobetti A, Schwartz J.  The lag structure between particulate air pollution and respiratory and cardiovascular deaths in ten US cities.  J Occup Environ Med, 2001; 43(11):927-933.

Brand KP, Catalano PJ, Hammitt JK, Rhomberg L, Evans JS.  Limitations to empirical extrapolation studies: the case of BMD ratios.  Risk Analysis, 2001; 21(4):625-640.

Cho E, Stampfer MJ, Seddon JM, Hung S, Spiegelman D, Rimm EB, Willett WC, Hankinson SE.  A prospective study of zinc intake and the risk of age-related macular degeneration.  Amer J Epidemiology, 2001; 11:328-336.

Evans JS, Rhomberg L, Williams PL, Wilson A, Baird SJ.  Reproductive and developmental risks from ethylene oxide: A probabilistic characterization of possible regulatory thresholds.  Risk Analysis, 2001; 21:697-717.

Guillemette C, DeVivo I, Hankinson SE, Haiman C, Speizer FE, Spiegelman D, Houseman DE, Hunter DJ.  Association of genetic polymorphisms in UGT1A1 with breast cancer and plasma hormone levels.  Cancer Epi Biomarkers Prev, 2001; 10:711-714.

Holmes LB, Coull BA, Harvey EA, Hayes AM.   Major malformations in anticonvulsant-exposed children: causal relationship or coincidence? (in Spanish). in Boletin Del ECEMC: Revista de Dismorfologia y Epidemiologia. Numero especial: 25 (1976-2001) (M. L. Martinez-Fr as, ed.) 2001;4:31-34.

Holmes LB, Harvey EA, Coull BA, Huntington KB, Khoshbin S, Hayes AM, Ryan LM.   The teratogenicity of antiepileptic drugs.  N E J Med, 2001; 344:1132-1138.

Janssen NAH, Schwartz J, Zanobetti A, Suh HH.  Air conditioning and percentage of PM10 emissions from different combustion sources as modifiers of the effect of ambient PM10 on hospital admissions for cardiovascular disease.  Epidemiology, 2001; 12:68.

Kobzik L, Goldsmith C-A W, Ning YY, Qin G, Morgan B, Imrich A, Lawrence J, Krishna Murthy GG, Catalano PJ.   Effects of combined ozone and air pollution particle exposure in mice.   Health Effects Institute 2001; 106:1-40.

Ku CH, Ryan L, Christiani D.  Skin test reactivity to fungi and dust mites and serum IgE concentrations in an occupational cohort.  Epidemiology, 2001; 12(4):295.

Ku CH, Ryan L, Christiani D.  An application of a Poisson model with GEE adjustments for assessment of occupational exposure to fungi.  Epidemiology, 2001; 12(4):298.

Levy JL, Houseman EA, Spengler JD, Loh P, Ryan L.  Fine particulate matter and polycyclic aromatic hydrocarbon concentration patterns in Roxbury, Massachusetts: A community-based GIS analysis.  Environ Health Perspec, 2001; 109:341-347.

Liu G, Miller DP, Zhou W, Thurston SW, Fan R, Xu L-L, Lynch TJ, Wain JC, Su L, and Christiani DC. Differential association of the codon 75 p53 and GSTM1 polymorphisms on histologic type of non-small cell lung carcinoma. Cancer Research, 2001; 61:8718-8722.

Long CM, Suh HH, Catalano PJ, Koutrakis P.  Using time-and size-resolved particulate data to quantify penetration and deposition behavior.  Env Sci & Tech, 2001; 35(10):2089-2099.

Long CM, Suh HH, Kobzik L, Catalano PJ, Ning YY, Koutrakis P.  A pilot investigation of the relative toxicity of indoor and outdoor particles; in vitro effects of endotoxin and other particulate properties.  Environ Health Perspec, 2001; 109:1019-1026.

Padungtod, Chantana, Ryan, L., et al. Occupational pesticide exposure and semen quality among Chinese workers. J Occupational & Environ Med, 2001; 42:982-992.

Park J-H, Spiegelman D, Gold DR, Burge HA, Milton DK.  House dust endotoxin and wheeze in the first year of life.  Amer J Respiratory & Critical Care Med, 2001; 163:322-328.

Park J-H, Spiegelman D, Gold DR, Burge HA, Milton DK.  Predictors of airborne endotoxin in the home.  Environ Health Perspec, 2001; 109:859-864.

Rogan WJ, Dietrich KN, Ware JH, Dockery DW, Salganik M, Radcliffe J, Jones RL, Ragan NB, Chisolm JJ, Rhoads GG for the TLC Group.  The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead.  NE J Med, 2001; 344:1421-1426.

Sarnat JA, Schwartz J, Catalano PJ, Suh HH.  Gasious pollutants in particulate matter eqidemiology: confounders or surrogates?  Environ Health Perspec, 2001; 109:1053-1061.

Schwartz J.  Is there harvesting in the association of airborne particles with daily deaths and hospital admission?  Epidemiol, 2001: 12:55-61.

Smith TJ, Lin YS, Mezzetti M, Bois FY, Kelsey K, Ibrahim J.  Genetic and dietary factors affecting human metabolism of 1,3-butadiene.  Chemico-Biological Interactions, 2001; 135:407-428.

Thurston SW. Biomarkers. In: El-Shaarawi AH and Piegorsch WW editors, Encyclopedia of Environmetrics, John Wiley and Sons, England, 2001; Vol 1:192-196.

Thurston SW. DNA adducts. In: El-Shaarawi AH and Piegorsch WW editors, Encyclopedia of Environmetrics, John Wiley and Sons, England, 2001; Vol 1:561-562.

Xu LL, Wain JC, Miller D, Thurston SW, Su L, and Christiani DC. The NAD(P)H:quinone oxidoreductase 1 gene polymorphism and lung cancer: differential susceptibility based on smoking behavior. Cancer Epidemiology Biomarkers & Prevention, 2001; 10:303-309.

Zhou W, Thurston SW, Liu G, Xu L-L, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC. The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer. Cancer Epidemiology Biomarkers & Prevention, 2001; 10:461-466.


Abt E, Suh H, Catalano PJ, Koutrakis P.  The relative contribution of outdoor and indoor particle sources to indoor concentrations.  Environ Sci & Tech, 2000; 34:3579-3587.

Chang LT, Koutrakis P, Catalano PJ, Suh HH.  Hourly personal exposures to fine particles and gaseous pollutants: results from Baltimore, MD.  J Air & Waste Management Assoc, 2000; 50:1223-1235.

Cheng Y, Kawachi I, Coakley EH, Schwartz J, Colditz GA.  Association between psychosocial work characteristics and health functioning in American women: prospective study.   British Med J, 2000; 320:1432-1436.

Clarke RW, Catalano P, Coull BA, Koutrakis P, Krishna Murthy GG, Rice T, Godleski JJ.  Age-related responses to concentrated urban air particles (CAPs).  Inhal Toxicol, 2000; 12:73-84.

Clarke RW, Coull BA, Reinisch U, Catalano PJ, Killingsworth CR, Koutrakis P, Kavouras I, Lawrence J, Lovett E, Wolfson JM, Verrier RL, Godleski JJ.  Inhaled concentrated ambient particles induce pulmonary inflammation and hematological changes in canines.  Environ Health Perspec, 2000; 108:1179-1187.

Fung TT, Hu FB, Yu J, Chu NF, Spiegelman D, Stampfer MJ, Willett WC, Rimm EB.  Leisure time physical activity, television watching, and plasma biomarkers of obesity and cardiovascular disease risk.  Amer J Epidemiology, 2000; 152:1171.1178.

Godleski JJ, Verrier RL, Koutrakis P, Catalano P, Coull BA, Reinisch U, Lovett EG, Lawrence J, Krishna Murthy GG, Wolfson JM, Clarke RW, Nearing BD.  Mechanisms of morbidity and mortality from exposure to ambient air particulate.  Health Effects Inst, 2000; Cambridge, MA.

Gold DR, Litonjua A, Schwartz J, Lovett E, Larson A, Nearing B, Allen G, Verrier M, Cherry R, Verrier R.  Ambient pollution and heart rate variability.  Circulation, 2000; 101:1267-1273.

Holmes LB, Rosenberger PB, Harvey EA, Khoshbin S, Ryan LM. Intelligence and physical features of children of women with epilepsy. Teratology, 2000; 61:196-202.

Laden F, Neas LM, Tolbert PE, Holmes MD, Hankinson SE, Spiegelman D, Speizer FE, Hunter DJ.  Electric blanket use and breast cancer in the Nurses' Health Study.  Amer J Epidemiology, 2000; 152:41-49.

Leuenberger P, Schindler C, Schwartz J, Ackermann-Leibrich U, Tara D, Perruchoud AP, Wuthrich B, Zellweger JP, Blaser K, Bolognini G, Bongard JP, Brandli O, Domenighetti G, Elsasser S, Grize L, Karrer W, Keller R, Kunzil N, Medici T, Schoni MH, Solari G, Tschopp JM, Villiger B, Zemp E.  Occupational exposure to inhalative irritants and methacholine responisveness.  Scand J Work Environ Health, 2000; 26:146-152.

Levy JI, Houseman EA, Ryan L, Richardson D, Students from the 1998 Summer Program in Biostatistics, Spengler JD.  Particle concentrations in urban microenvironments.  Enviro Health Perspec, 2000;108:1051-1057.

Long NC, Abraham J, Kobzik L, Weller EA, Krishna Murthy GG, Shore SA.  Respiratory tract inflammation during induction of chronic bronchitis in rats: role of C-fibers.  Eur Resp J, 2000; 14:46-56.

Lu MCK, Sammel MD, Cleveland RH, Ryan LM, Holmes, LB. Digit effects produced by prenatal exposure to antiepileptic drugs. Teratology, 2000; 61(4):277-283.

Moore PE, Laporte JD, Abraham JH, Schwartzman IN, Yandava CN, Silverman ES, Drazen JM, Wand MP, Panettieri R, Shore SA.  Polymorphism of the beta 2 adrenergic receptor gene and densensitization in human airway smooth muscle.  Amer J Respiratory & Critical Care Med, 2000; 162:2117-2124.

Morales KH, Ryan L, Kuo TL, Wu MM, Chen CJ.  Risk of internal cancers from arsenic in drinking water.  Environ Heatlh Perspec, 2000; 108:655-661.

Park J-H, Spiegelman D, Burge HA, Gold DR, Chew GL, Milton DK.  A longitudinal study of dust and airborne endotoxin in the home.  Environ Health Perspec, 2000; 108:1023-1028.

Peters A, Liu E, Verrier RL, Schwartz J, Gold DR, Mittleman M, Baliff J, Oh A, Allen G, Monahan K, Dockery D.  Air pollution and incidence of cardiac arrythmia.  Epidemiol, 2000; 11:11-17.

Schwartz J.  Harvesting and long-term exposure effects in the relationship between air pollution and mortality.  Am J Epidemiol, 2000; 151:440-448.

Schwartz J.  The distributed lag between air pollution and daily deaths.  Epidemiol, 2000; 11:320-26.

Schwartz J, Levin R, Goldstein R.  Drinking water turbidity and gastrointestinal illness in Philadelphia's elderly.  J Epid Comm Health, 2000; 54:45-51.

Schwartz J and Neas LM.  Fine particles are more strongly associated than coarse particles with acute respiratory health effects in children.  Epidemiol, 2000; 11:6-10.

Schwartz J, Timonen KL, Pekkanen J.  Respiratory effects of environmental tobacco smoke in a panel study of asthmatic and symptomatic children.  Am J Respir Crit Care Med, 2000; 161:802-806.

Schwartz J and Zanobetti A.  Using meta-smoothing to estimate dose-response trends across multiple studies, with application to air pollution and daily death.  Epidemiol, 2000; 11(6):666-672.

Stoler JM, McGuirk CK, Lieberman E, Ryan LM, Holmes LB. Malformations reported in chorionic villus sampling exposed children: A review and analytic synthesis of the literature. Genetics Med, 2000; 1(7): 315-322.

Sunyer J, Schwartz J, Tobias A, Macfarlane D, Garcia J, Anto JM.  Patients with chronic obstructive  pulmonary disease are at increased risk of death associated with urban particle air pollution: a case-crossover analysis.  Am J Epidemiol, 2000; 151:50-6.

Thurston SW, Ryan L, Christiani DC, Snow R, You L, Cui S, Ma G, Wang L, Huang Y, Xu X.  Petrochemical exposure and menstrual disturbances.   Amer J Indust Med, 2000; 38:555-564.

Treatment of Lead-exposed Children (TLC) Trial Group (includes Salganik M).  Safety and efficiency of Succimer in toddlers with blood lead levels of 20-44 microg/dl.  Pediat Res, 2000; 48:593-599.

Wechsler ME, Grasemann H, Deykin A, Silverman EK, Yandava CN, Isreal E, Wand M, Drazen JM.  Exhaled nitric oxide in patients with astmas: Association with NOS1 genotype.  Amer J Respiratory & Critical Care Med, 2000; 162:2043-2047.

Zanobetti A and Schwartz J.  Race, gender and social status as modifiers of the effects of PM10 on mortality.  J Occup Environ Med, 2000; 42:469-74.

Zanobetti A, Schwartz J, Gold DR.  Are there sensitive subgroups for the health effects of airborne particles?  Environ Health Perspect, 2000; 108(9):841-845.

Zeger SL, Thomas D, Dominici F, Samet J, Schwartz J, Dockery D, Cohen A.  Exposure measurement error in time-series studies of air pollution: concepts and consequences.  Environ Health Perspect, 2000; 108:419-26.


Anderson HR, Quenel P, Katsouyanni K, Zanobetti A, Sunyer J, Schouten JP, Wojtyniak B, Zmirou D, Bacharova L, Ponka A, Wichmann HE.  Recommendations for the monitoring of short-term health effects of air pollution: lessons from the APHEA Multi Centre European Study.  Zentralbl Hyg Umweltmed, 1999; 202:471-88.

Bateson T and Schwartz J.  Control for seasonal variation and time trend in case-crossover studies of acute effects of environmental exposures.  Epidemiol, 1999; 54:596-605.

Cho S-I, Qian L, Yang J, Chen C, Padungtod C, Ryan L, Christiani DC, Xu X. Drinking water source and spontaneous abortion: a cross-sectional study in a rural Chinese population. Int J Occup Environ Health, 1999; 5:164-169.

Christiani DC, Ye T-T, Zhang S, Wegman DH, Eisen EA, Ryan LA, Olenchock SA, Pothier L, Dai H-L. Cotton dust and endotoxin exposure and long-term decline in lung function: results of a longitudinal study. Am J Industrial Med, 1999; 35:321-331.

Clarke RW, Catalano PJ, Koutrakis P, Krishna Murthy GG, Sioutas C, Paulauskis J, Coull B, Ferguson S, Godleski JJ.  Urban air particulate inhalation alters pulmonary function and induces pulmonary inflammation in a rodent model of chronic bronchitis.  Inhal Toxicol, 1999; 11:101-120.

Clarke RW, Catalano PJ, Koutrakis P, Krishna Murthy GG, Sioutas C, Paulauskis J, Coull BA, Ferguson S, Godleski JJ.  Urban air particulate inhalation alters pulmonary function and induces pulmonary inflammation in a rodent model of chronic bronchitis.  Inhal Toxicol, 1999; 11:637-656.

Coull BC, Greenwood JG, Fielder DR, Coull BA.  Subtropical Australian juvenile fish eat meiofauna: experiments with winter whiting Silago maculataI and observations on other species.  Marine Ecology Progress Series, 1999; 125:13-19.

Garcia-Closas M, Kelsey KT, Hankinson SE, Spiegelman D, Springer K, Willett WC, Speizer FE, Hunter DJ.  Glutathione S-transferase class mu and theta polymorphisms and breast cancer suscepibility.  J NCI, 1999; 91:1960-1964.

Goldsmith C-AW, Hamada K, Ning Y, Gin G, Catalano PJ, Krishna Murthy GG, Lawrence J, Kobzik L.  The effects of environmental aerosols on airway hyperresponsiveness in a murine model of asthma.  Inhal Toxicol, 1999; 11(11):981-998.

Haiman C, Hankinson SE, Spiegelman D, Colditz GA, Willett WC, Speizer FE, Kelsey KT, Hunter DJ.  The relationship between a polymorphism in CYP17 with hormone levels and breast cancer.  Cancer Research, 1999; 59:1015-1020.

Imrich A, Ning YY, Koziel H, Coull BA, Kobzik L.  Lipopolysaccaride priming amplifies lung macrophage tumor necrosis factor production in response to air particles.  Toxicology & Applied Pharmacology, 1999; 159:117-124.

Ku CH, Burge HA, Ryan LM, Pai L, Liou SH, Christiani DC.  Rice field fungal exposures in young male workers: short-term exposure assessment for fungi.  Am J Resp & Crit Care Med, 1999; 159(3):A298-A298.

Lee JT and Schwartz J.  Reanalysis of the effects of air pollution on daily mortality in Seoul, Korea: A case-crossover design.  Environ Health Perspect, 1999; 107:633-636.

Lin AE, Herring AH, Amstutz KS, Westgate M-N, Lacro RV, Al-Jufan , Ryan LM, Holmes LB. Cardiovascular malformations: changes in prevalence and birth status. Am J Medical Genetics, 1999; 84: 102-110.

Long NC, Skornik WA, Kobzik L, Weller EA, Shore SA.  Respiratory tract inflammation during induction of chronic bronchitis in rats: role of c-fibers.  Eur Resp J, 1999; 14:46-56.

Massaro AF, Coulston EL, Foster J, Devkin A, Yim E, Mazzella L, Wand MP, Salganik MP, Israel E, Drazen JM.  Diurnal variation in expired nitric oxide (NO) in asthmatics.  Amer J Respiratory & Critical Care Med, 1999; 159(3):A860-A860.

Padungtod C, Hassold TJ, Millie E, Ryan LM, Savitz DA, Christiani DC, Xu X.  Sperm aneuploidy among Chinese pesticide factory workers: Scoring by the FISH method.  Amer J Indust Med, 1999; 36:230-238.

Padungtod C, Niu TH, Wang ZX, Savitz DA,Christiani DC, Ryan LM, Xu XP.  Paraoxonase polymorphism and its effecton male reproductive outcomes among Chinese pesticide factory workers.  Amer J Indust Med, 1999; 36:379-387.

Pope CA, Dockery DW, Kanner RE, Villegas GM, Schwartz J.  Oxygen saturation, pulse rate, and particulate air pollution: a daily time series panel study.  Am J Resp Crit Care Med, 1999; 159:365-372.

Pope CA, Verrier RL, Lovett EG, Larson AC, Raizenne ME, Kanner RE, Schwartz J, Villegas GM, Gold DR, Dockery DW.  Heart rate variability associated with particulate air pollution.  Am Heart J, 1999; 138:890-899.

Rimm EB, Williams PL, Fosher K, Criqui M, Stampfer MJ.  A biologic basis for moderate alcohol consumption and lower coronary heart disease risk: A meta-analysis of effects on lipids and hemostatic factors.  British Med J, 1999; 319:1523-1528.

Rossi G, Vigotti MA, Zanobetti A, Repetto F, Gianelle V, Schwartz J.  Air pollution and cause specific mortality in Milan, Italy 1980-1989.  Arch Environ Health, 1999; 54:158-164.

Schwartz J.  Air pollution and hospital admissions for heart disease in eight US counties.  Epidemiol, 1999; 10:17-22.

Schwartz J and Levin R. Drinking water turbidity and health.  Epidemiol, 1999; 10:86-90.

Schwartz J, Norris G, Larson T, Sheppard L, Claiborne C, Koenig J.  Episodes of high coarse particle concentrations are not associated with increased mortality.  Environ Health Perspect, 1999; 107:339-342.

Tsaih S-W, Schwartz J, Lee M-L T, Amarasiriwardena C, Aro A, Sparrow D, Hu H. The independent contribution of bone and erythrocyte lead to urinary lead among middle-aged and elderly men: The normative again study.  Environ Health Perspec, 1999; 107:339-342.

Weller E, Long N, Smith A, Hennessey R, Williams P, Ravi S, Gill J, Skornik W, Kimmel C, Kimmel G, Holmes L, Ryan L.  Developmental toxicity of short term exposure to ethylene oxide.  Toxicol Sci, 1999; 50:259-270.

Weller E, Long N, Smith A, Williams P, Ravi S, Gill J, Henessey R, Skornik W, Brain J, Kimmel C, Kimmel G, Holmes L, Ryan L. Dose-rate effects of ethylene oxide exposure on developmental toxicity. Toxicol Sci, 1999; 50:259-270.

Wiencke JK, Thurston SW, Kelsey KT, Varkonyi A, Wain JC, Mark EJ, and Christiani DC. Early age at smoking initiation and tobacco carcinogen DNA damage in the lung, J NCI, 1999; 91:614-619.


Chen J, Giovannucci EL, Hankinson SE, Willett WC, Spiegelman D, Kelsey KT, Hunter DJ.  A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms and risk of colorectal adenoma.  Carcinogenesis, 1998; 19:2129-2132.

Cheng Y, Willet W, Schwartz J, Sparrow D, Weiss ST, Hu, H.  The relationship of nutrition to bone lead and blood levels in middle-aged to elderly men: the normative aging study.  Am J Epidemiol, 1998; 147:1162-74.

Frevert CW, Weller EA, Warner AE, Brian JD.  The effect of endotoxin on in vivo alveolar macrophage phagocytosis.  Experimental Lung Research, 1998; 24:745-758.

Gaylor D, Ryan L, Krewski D, Zhu Y. Procedures for calculating benchmark doses for health risk assessment. Regulatory Toxicol & Pharmacol, 1998; 28:150-164.

Godleski JJ, Verrier RL, Koutrakis P, Catalano PJ, Reinisch V, Lovett EG, Lawrence J, Coull B, Krishna Murthy GG, Wolfson JM, Clarke RW, Nearing BD, Killingsworth C.  Mechanisms of morbidity and mortality from exposure to ambient air particulate.  Health Effects Institute Research Report, Cambridge, MA, 1998.

Ishibe N, Hankinson SE, Colditz GA, Spiegelman D, Willett W, Speizer FE, Kelsey KT, Hunter DJ.  A prospective study of cytochrome P450 1A1 polymorphisms and breast cancer risk in the Nurses' Health Study.  Cancer Research, 1998; 58:667-671.

Lanphear BP, Matte TD, Clickner R, Dietz B, Rogers J, Bornschein RI, Succop P, Mahaffey KR, Dixon S, Galke W, Rabinowitz M, Farfel M, Rhode C, Schwartz J, Ashley P, Jacobs DE.  The contribution of lead contaminated housedust and residential soil to children's blood lead levels.  Environ Res, 1998; 79:51-68.

Neas LM and Schwartz J.  Pulmonary function levels as predictors of mortality in a national sample of US adults.  Am J Epidemiol, 1998; 147:1011-1017.

Ozkaynak H, Spengler JD, Jaakkola JJK, Ford T, Xue J, Agorov A, Schwartz J, Kuzmin S, Rakitin P, Privalova L, Chebotarkova S, Zemlianaia G.  Evaluation of existing environmental information systems in Russia applicable for human health effects assessment.  In: Air pollution in the Ural Mountains (I. Linkov, R. Wilson, eds.) NATO ASI Series, Kluwer Academic Publishers, Dordrecht, Netherlands 1998; 195-217.

Padungtod C, Lasley BL, Christiani DC, Ryan LM, Xu X. Reproductive hormone profile among pesticide factory workers. J Occup Environ Med, 1998; 40(12):1038-47.

Roemer W, Hoek G, Brunekreef B, Schouten JP, Baldini G, Clench-Aas J, Engler N, Fischer P, Forsberg B, Haluszka J, Kalandidi A, Kotesovec F, Niepsj G, Pekkanen J, Rudnai P, Skerfving S, Vondra V, Wichmann HE, Dockery DW, Schwartz J.  Effect of short-term changes in urban air pollution on the respiratory health of children with chronic respiratory symptoms: the PEACE project: Introduction.  European Respir Rev, 1998; 8:(52)4-11.

Schwartz J.  Health effects of particulate air pollution: Is there a threshold?  In Mohr U. Ed. Relationship between Respiratory Disease and Exposure to Air Pollution.  ILSI Press, Washington DC, 1998.

Spix C, Anderson HR, Schwartz J, Vigotti M, le Tertre A, Vonk JM, Touloumi G, et al.  Short term effects of air pollution on hospital admission of respiratory disease in Europe: a quantitative summary of APHEA study results.  Arch Environ Health, 1998; 53:54-64.

Stoler JM, Huntington KS, Peterson CM, Peterson KP, Daniel P, Aboagye KK, Lieberman E, Ryan LM, Holmes LB. The prenatal detection of significant alcohol exposure with maternal blood markers. J Pediatrics, 1998; 133:346-52.

Xu X, Cho SI, Sammel M, You L, Cui S, Huang Y, Ma G, Padungtod C, Pothier L, Niu T, Christiani D, Smith T, Ryan L, Wang L. Association of petrochemical exposure with spontaneous abortion. J Occup Environ Med, 1998; 55(1):31-6.

Zmirou D, Schwartz J, Saez M, Zanobetti A, Wojtymiak B, Touloumi G, Spix C, Ponce de Leon A, LeMoullec Y, Bacharova L, Schouten J, Ponka A, Katsouyanni K.  Time series analysis of air pollution and cause specific mortality: a quantitative summary in Europe (APHEA study). Epidemiol, 1998; 9(5):495-503.


Anderson HR, Spix C, Medina S, Schouten JP, Castellsague J, Rossi A, Zmirou D, Touloumi G, Wojtynaik B, Ponka A, Bacharova L, Schwartz J, Katsouyanni K.  Air pollution and daily admissions for chronic obstructive pulmonary disease in 6 European cities: results from the APHEA project.  Eur Resp J, 1997; 10:1064-71.

Baird SJS, Catalano PJ, Ryan LM.  Evaluation of effect profiles: functional observational battery outcomes.  Fund & Applied Toxicol, 1997; 40:37-51.

Catalano PJ, McDaniel KL, Moser VC.  The IPCS collaborative study on neurobehavioral screening methods: VI.  Agreement and reliability of the data.  Neurotoxicology, 1997; 18(4):1057-1064.

Glencross PM, Weinberg JM, Ibrahim JG, Christiani DC.  Loss of lung function among sheet metal workers: Ten year study.  Amer J Indust Med, 1997; 32:460-466.

Harkema JR, Catalano PJ, Hotchkiss JA.  Consequences of prolonged inhalation of ozone in F344/N rats: Collaborative Studies.  Part XII: Atrophy of Bone in Nasal Turbinates,  Research Report Number 65, Part XII.  Health Effects Institute, Cambridge, MA, 1997.

Hoek G, Schwartz J, Groof B, Eler P.  Effects of ambient particulate matter and ozone on daily mortality in Rotterdam, the Netherlands.  Arch Environ Health, 1997; 52:455-463.

Kelsey KT, Hankinson S, Colditz G, Springer K, Garcia-Closas M, Spiegelman D, Manson J, Garland M, Stampfer M, Willett W, Speizer F, Hunter DJ.  Glutathione S-transferase class I deletion polymorphism and breast cancer: results from prevalent vs. incident cases.  Cancer Epidem Biomarkers & Prevention, 1997; 6:511-515.

Killingsworth CR, Alessandri F, Krishna Murthy GG, Catalano PJ, Paulauskis JD, Godleski JJ.  Inflammation, Chemokine expression and death in monocrotaline-treated rats following fuel oil fly ash inhalation.  Inhal Toxicol, 1997; 9:541-565.

Laden F, Wolff MS, Niguidula NJ, Spiegelman D, Hankinson SE, Hunter DJ.  Comparison of accuracy and precision of organochlorine assay using different size aliquots.  Cancer Epidem Biomarkers & Prevention, 1997; 6-333-338.

MacIntosh DL, Williams PL, Hunter DJ, Morris SC, Willett WC, Rimm EB.  Evaluation of a food frequency questionnaire-food consumption approach for estimating dietary intake of inorganic arsenic and methylmercury. Cancer Epidemiol, 1997; 6:1043-1050.

Schwartz J.  Air pollution and hospital admissions for cardiovascular disease in Tuscon.  Epidem, 1997; 8:371-377.

Stark PC, Ryan LM, McDonald JL, Burge HA.  Using meterologic data to predict daily ragweed pollen levels.  Aerobiologia, 1997; 13:177-184.

Sunyer J, Spix C, Quenel P, Ponce de Leon A, Ponka A, Barumandzadeh T, Touloumi G, Bacharova L, Wojtyniak B, Vonk J, Bisanti L, Schwartz J, Katsouyanni K.  Urban air pollution and emergency admissions for asthma in four European cities: the APHEA project.  Thorax, 1997; 52:760-65.

Weller EA, Ryan LM, Spiegelman D, Smith T. Statistical issues in assessing human population exposures. Chemometrics & Intelligent Laboratory Systems, 1997; 37:189-195.