Harvard School of Public Health
Department of Biostatistics

Psychiatric Biostatistics


Select Publications

Reich DB, Zanarini MC, Fitzmaurice G. (2011) Affective lability in bipolar disorder and borderline personality disorder. Compr Psychiatry. 2011 May 30. [Epub ahead of print]

Horvitz-Lennon M, Zhou D, Normand SL, Alegría M, Thompson WK. (2011) Racial and Ethnic Service Use Disparities Among Homeless Adults With Severe Mental Illnesses Receiving ACT. Psychiatr Serv. ; 62(6):598-604.

Yoon FB, Fitzmaurice GM, Lipsitz SR, Horton NJ, Laird NM, Normand SL. (2011) Alternative methods for testing treatment effects on the basis of multiple outcomes: Simulation and case study. Stat Med.; 30(16):1917-32.

Lê Cook B, McGuire TG, Alegría M, Normand SL. (2011) Crowd-out and Exposure Effects of Physical Comorbidities on Mental Health Care Use: Implications for Racial-Ethnic Disparities in Access. Health Serv Res. ; 46(4):1259-80.

Paradis AD, Giaconia RM, Reinherz HZ, Beardslee WR, Ward KE, Fitzmaurice GM. (2011) Adolescent Family Factors Promoting Healthy Adult Functioning: A Longitudinal Community Study. Child Adolesc Ment Health.; 16(1):30-37.

Goldstein JM, Cherkerzian S, Seidman LJ, Petryshen TL, Fitzmaurice G, Tsuang MT, Buka SL. (2011) Sex-specific rates of transmission of psychosis in the New England high-risk family study. Schizophr Res.; 128(1-3):150-5.

McDonald LJ, Griffin ML, Kolodziej ME, Fitzmaurice GM, Weiss RD. (2011) The impact of drug use in social networks of patients with substance use and bipolar disorders. Am J Addict.; 20(2):100-5.

Zanarini MC, Frankenbur FR, Weingeroff JL, Reich DB, Fitzmaurice GM, Weiss RD. (2011) The course of substance use disorders in patients with borderline personality disorder and Axis II comparison subjects: a 10-year follow-up study. Addiction.; 106(2):342-8.

Neelon BH, O'Malley AJ, Normand SL. (2010) A Bayesian model for repeated measures zero-inflated count data with application to outpatient psychiatric service use. Stat Modelling. ; 10(4):421-439.

Roberts AL, Gilman SE, Fitzmaurice G, Decker MR, Koenen KC. <2010) Witness of intimate partner violence in childhood and perpetration of intimate partner violence in adulthood. Epidemiology.; 21(6):809-18.

Meyer RE, Salzman C, Youngstrom EA, Clayton PJ, Goodwin FK, Mann JJ, Alphs LD, Broich K, Goodman WK, Greden JF, Meltzer HY, Normand SL, Posner K, Shaffer D, Oquendo MA, Stanley B, Trivedi MH, Turecki G, Beasley CM Jr, Beautrais AL, Bridge JA, Brown GK, Revicki DA, Ryan ND, Sheehan DV. <2010) Suicidality and risk of suicide--definition, drug safety concerns, and a necessary target for drug development: a consensus statement. J Clin Psychiatry. ; 71(8):e1-e21.

Hörz S, Zanarini MC, Frankenburg FR, Reich DB, Fitzmaurice G. (2010) Ten-year use of mental health services by patients with borderline personality disorder and with other axis II disorders. Psychiatr Serv.; 61(6):612-6.

Ball SW, Gilman SE, Mick E, Fitzmaurice G, Ganz ML, Seidman LJ, Buka SL. (2010) Revisiting the association between maternal smoking during pregnancy and ADHD. J Psychiatr Res.; 44(15):1058-62.

Troxel AB, Lipsitz SR, Fitzmaurice GM, Ibrahim JG, Sinha D, Molenberghs G. (2010) A weighted combination of pseudo-likelihood estimators for longitudinal binary data subject to non-ignorable non-monotone missingness. Stat Med.; 29(14):1511-21.

Stuart EA, Marcus SM, Horvitz-Lennon MV, Gibbons RD, Normand SL. (2009) Using Non-experimental Data to Estimate Treatment Effects. Psychiatr Ann. ; 39(7):41451.

Neelon B, O'Malley AJ, Normand SL. (2011) A bayesian two-part latent class model for longitudinal medical expenditure data: assessing the impact of mental health and substance abuse parity. Biometrics. ; 67(1):280-9.

Teixeira-Pinto A, Siddique J, Gibbons R, Normand SL. (2009) Statistical Approaches to Modeling Multiple Outcomes In Psychiatric Studies. Psychiatr Ann. ; 39(7):729-735.

Busch AB, Huskamp HA, Neelon B, Manning T, Normand SL, McGuire TG. (2009) Longitudinal racial/ethnic disparities in antimanic medication use in bipolar-I disorder. Med Care. ; 47(12):1217-28.

Marcus SM, Siddique J, Have TR, Gibbons RD, Stuart E, Normand SL. (2008) Balancing Treatment Comparisons in Longitudinal Studies. Psychiatr Ann. ; 38(12):805-811.

Fitzmaurice GM, Ravichandran C. (2008) A primer in longitudinal data analysis. Circulation.; 118(19):2005-10.

Ravichandran C, Fitzmaurice GM. (2008) To dichotomize or not to dichotomize? Nutrition.; 24(6):610-1.

Skeer M, McCormick MC, Normand SL, Buka SL, Gilman SE. (2009) A prospective study of familial conflict, psychological stress, and the development of substance use disorders in adolescence. Drug Alcohol Depend. ; 104(1-2):65-72.

Gill SS, Anderson GM, Fischer HD, Bell CM, Li P, Normand SL, Rochon PA. (2009) Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: a population-based cohort study. Arch Intern Med. ; 169(9):867-73.

Horvitz-Lennon M, Donohue JM, Domino ME, Normand SL. (2009) Improving quality and diffusing best practices: the case of schizophrenia. Health Aff (Millwood).; 28(3):701-12.

Busch AB, Frank RG, Sachs G, Normand SL. (2009) Bipolar-I patient characteristics associated with differences in antimanic medication prescribing. Psychopharmacol Bull. ; 42(1):35-49.

Ten Have TR, Normand SL, Marcus SM, Brown CH, Lavori P, Duan N. (2008) Intent-to-Treat vs. Non-Intent-to-Treat Analyses under Treatment Non-Adherence in Mental Health Randomized Trials. Psychiatr Ann. ; 38(12):772-783.

Rochon PA, Normand SL, Gomes T, Gill SS, Anderson GM, Melo M, Sykora K, Lipscombe L, Bell CM, Gurwitz JH. (2008) Antipsychotic therapy and short-term serious events in older adults with dementia. Arch Intern Med. ; 168(10):1090-6.

Breslau J, Javaras KN, Blacker D, Murphy JM, Normand SL. (2008) Differential item functioning between ethnic groups in the epidemiological assessment of depression. J Nerv Ment Dis..; 196(4):297-306.

Alegría M, Polo A, Gao S, Santana L, Rothstein D, Jimenez A, Hunter ML, Mendieta F, Oddo V, Normand SL. (2008) Evaluation of a patient activation and empowerment intervention in mental health care. Med Care. ; 46(3):247-56.

Gill SS, Bronskill SE, Normand SL, Anderson GM, Sykora K, Lam K, Bell CM, Lee PE, Fischer HD, Herrmann N, Gurwitz JH, Rochon PA. (2007) Antipsychotic drug use and mortality in older adults with dementia. Ann Intern Med.; 146(11):775-86.

Wilkins KJ, Fitzmaurice GM. (2007) A marginalized pattern-mixture model for longitudinal binary data when nonresponse depends on unobserved responses. Biostatistics.; 8(2):297-305.

Azrin ST, Huskamp HA, Azzone V, Goldman HH, Frank RG, Burnam MA, Normand SL, Ridgely MS, Young AS, Barry CL, Busch AB, Moran G. (2007) Impact of full mental health and substance abuse parity for children in the Federal Employees Health Benefits Program. Pediatrics.; 119(2):e452-9.

Dickey B, Normand SL, Eisen S, Hermann R, Cleary P, Cortés D, Ware N. (2006) Associations between adherence to guidelines for antipsychotic dose and health status, side effects, and patient care experiences. Med Care.; 44(9):827-34.

Clements KM, Murphy JM, Eisen SV, Normand SL. (2006) Comparison of self-report and clinician-rated measures of psychiatric symptoms and functioning in predicting 1-year hospital readmission. Adm Policy Ment Health.; 33(5):568-77.

Timbie JW, Horvitz-Lennon M, Frank RG, Normand SL. (2006) A meta-analysis of labor supply effects of interventions for major depressive disorder. Psychiatr Serv.; 57(2):212-8.

O'Brien LM, Fitzmaurice GM, Horton NJ. <2006) Maximum likelihood estimation of marginal pairwise associations with multiple source predictors. Biom J.; 48(5):860-75.

Monuteaux MC, Blacker D, Biederman J, Fitzmaurice G, Buka SL. <2006) Maternal smoking during pregnancy and offspring overt and covert conduct problems: a longitudinal study. J Child Psychol Psychiatry.; 47(9):883-90.

Yu JW, Buka SL, Fitzmaurice GM, McCormick MC. (2006) Treatment outcomes for substance abuse among adolescents with learning disorders. J Behav Health Serv Res.; 33(3):275-86.

Liu IC, Xu R, Blacker DL, Fitzmaurice G, Lyons MJ, Tsuang MT. (2005) The application of a random effects model to censored twin data. Behav Genet.; 35(6):781-9.

O'Brien LM, Fitzmaurice GM. (2005). Regression models for the analysis of longitudinal Gaussian data from multiple sources. Statistics in Medicine;24(11):1725-44.

O'Malley AJ, Normand S-LT. (2005) Likelihood methods for treatment-noncompliance and subsequent nonresponse in randomized trials. Biometrics; 61(2):325-34.

Tchernis R, Horvitz-Lennon M, Normand S-LT. (2005) On the use of discrete choice models for causal inference. Statistics in Medicine; 24(14):2197-2212.

Daniels MJ, Normand S-LT. (2006) Longitudinal profiling of health care units based on continuous and discrete patient outcomes. Biostatistics; 7(1):1-15.

Reinherz HZ, Tanner JL, Berger SR, Beardslee WR, Fitzmaurice GM. (2006). Adolescent suicidal ideation as predictive of psychopathology, suicidal behavior and compromised functioning at age 30. American Journal of Psychiatry;163(7):1226-32.

Horvitz-Lennon M, O'Malley AJ, Frank RG, Normand S-LT. (2005) Improving traditional intention-to-treat analyses: A new approach. Psychological Medicine, 35:1-10.

McGrath E, Wypij D, Rappaport LA, Newburger JW, Bellinger DC. (2004) Prediction of IQ and Achievement at Age 8 Years From Neurodevelopmental Status at Age 1 Year in Children with D-transposition of the Great Arteries. Pediatrics, 114:e572-6.

Monuteaux MC, Fitzmaurice GM, Blacker D, Buka SL, Biederman J. (2004). Specificity in the familial aggregation of overt and covert conduct disorder symptoms in a referred ADHD sample. Psychological Medicine, 34: 1113-1127.

Horton, N.J. and Fitzmaurice, G.M.. (2004). Tutorial in biostatistics: regression analysis of multiple source and multiple informant data from complex survey samples. Statistics in Medicine, 23(18):2911-2933.

Liu I-C, Blacker DL, Xu R, Fitzmaurice GM, Tsuang MT, Lyons MJ. (2004). Genetic and environmental contributions to age of onset of alcohol dependence symptoms in male twins. Addiction, 99:1403-1409.

Liu I-C, Blacker DL, Xu R, Fitzmaurice GM, Tsuang MT, Lyons MJ. (2004). Genetic and environmental contributions to the development of alcohol dependence in male twins. Archives of General Psychiatry, 61:897-903.

O'Brien, L.M. and Fitzmaurice, G.M. (2004). Analysis of longitudinal multiple-source binary data using generalized estimating equations. Journal of the Royal Statistical Society: Series C (Applied Statistics), 5(1):177-193.

Levy DE, O'Malley AJ, Normand S-LT. (2004) Covariate adjustment in clinical trials with non-ignorable missing data and non-compliance. Statistics in Medicine, 23:2319-2339.

Rubio-Stipec, M., Fitzmaurice, G.M., Murphy, J.M. and Walker, A. (2003). The use of multiple informants in identifying the risk factors of depressive and disruptive disorders: are they interchangeable? Social Psychiatry and Psychiatric Epidemiology, 38(2):51-58.

Gilman SE, Kawachi I, Fitzmaurice GM, Buka SL. (2003). Family disruption in childhood and risk of adult depression. American Journal of Psychiatry, 160:939-946.

Lipsitz SR, Parzen M, Fitzmaurice GM, Klar N. (2003). A two-stage logistic regression model for analyzing inter-rater agreement. Psychometrika, 68:289-298.

Reinherz HZ, Paradis AD, Giaconia RM, Stashwick CK, Fitzmaurice G. (2003). Childhood and adolescent predictors of major depression in the transition to adulthood. American Journal of Psychiatry, 160:2141-2147.

Rubio-Stipec, M., Walker A., Murphy, J.M. and Fitzmaurice, G.M (2002). Dimensional measures of psychopathology: the probability of being classified with a psychiatric disorder using empirically derived symptom scales. Social Psychiatry and Psychiatric Epidemiology, 37(12):553-560.

Gilman SE, Kawachi I, Fitzmaurice GM, Buka SL. (2003). Socioeconomic status, family disruption and residential stability in childhood: relation to onset, recurrence and remission of major depression. Psychological Medicine, 33:1341-1355.

Landrum MB, Normand S-LT, Rosenheck RA. (2003) Selection of related multivariate means: Monitoring psychiatric care in the Department of Veterans Affairs. Journal of the American Statistical Association, 98(461):7-16.

Dickey BD, Normand S-LT, Hermann R, Eisen SV, Cortes D, Cleary P, Ware N. (2003) Guideline recommendations for treatment of schizophrenia: The impact of managed care. Archives of General Psychiatry, 60:340-348.

Mick E, Biederman J, Santangelo S, Wypij D. (2003) The Influence of Gender in the Familial Association between ADHD and Major Depression. Journal of Nervous and Mental Disease, 191:699-705.

Bellinger DC, Wypij D, du Plessis AJ, Rappaport LA, Jonas RA, Wernovsky G, Newburger JW. (2003) Neurodevelopmental Status at Eight Years in Children with Dextro-transposition of the Great Arteries: The Boston Circulatory Arrest Trial. Journal of Thoracic and Cardiovascular Surgery, 126:1385-1396.

Wypij D, Newburger JW, Rappaport LA, du Plessis AJ, Jonas RA, Wernovsky G, Lin M, Bellinger DC. (2003) The Effect of Duration of Deep Hypothermic Circulatory Arrest in Infant Heart Surgery on Late Neurodevelopment: The Boston Circulatory Arrest Trial. Journal of Thoracic and Cardiovascular Surgery, 126:1397-1403.

Rubio-Stipec, M., Fitzmaurice, G.M., Murphy, J.M. and Walker, A. (2003) The use of multiple informants in identifying the risk factors of depressive and disruptive disorders: Are they interchangeable? Social Psychiatry and Psychiatric Epidemiology, 38(2):51-58.

Horton, N.J. and Fitzmaurice, G.M. (2002). Maximum likelihood estimation of bivariate logistic models for incomplete responses with indicators of ignorable and non-ignorable missingness. Applied Statistics, 51(3):281-295.

Berndt ER, Bir A, Busch SH, Frank RG, Normand S-LT. (2002) The medical treatment of depression, 1991-1996: Productive inefficiency, expected outcome, and price indexes. Journal of Health Economics, 21(3):373-396.

Normand S-LT, Frank RG, McGuire TG. (2002) Using elicitation techniques to estimate the value of ambulatory treatments for major depression. Medical Decision Making, 22:245-261.

Daskalakis, C., Laird, N.M., and Murphy, J.M. (2002) Regression analysis of multiple-source longitudinal outcomes: A "Stirling County" depression study. American Journal of Epidemiology, 155(1):88-94.

Goldwasser M and Fitzmaurice GM. (2001) Multivariate linear regression analysis of childhood psychopathology using multiple informant data. International Journal of Methods in Psychiatric Research, 10:1-10.

Hudson J.I., Laird, N.M. and Betensky R.A. (2001) Multivariate logistic regression for familial aggregation of two disorders: I. Development of models and methods. American Journal of Epidemiology, 153:500-505.

Horton, N.J., Laird, N.M., Murphy, J.M., Monson, R.R, Sobol, A.M and Leighton, A.H. (2001) Multiple informants: Mortality associated with psychiatric disorders in the Stirling County Study. American Journal of Epidemiology, 154(7):649-656.

Fitzmaurice, GM and Laird NM. (2000) Generalized linear mixture models for handling nonignorable dropouts in longitudinal studies. Biostatistics, 1:141-156.

Bassuk SS, Wypij D, Berkman LF. (2000) Cognitive impairment and mortality in the community-dwelling elderly. American Journal of Epidemiology, 151:676-88.

Laird N.M., Horvath S., and Xu X. (2000) Implementing a unified approach to family-based tests of association. Genetic Epidemiology, 19(Suppl 1):S36-S42.

Lake S., Blacker D., Laird N.M. (2000) Family-based tests of association in the presence of linkage. American Journal of Human Genetics, 67:1515-1525.

Testa MA. (2000) Interpretation of quality of life outcomes: Issues that affect magnitude and meaning. Medical Care, 38 [suppl II]:II-166-II-174.