Interdisciplinary Grant in Biostatistics
 


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QUALIFICATIONS

Students must be PhD students in the department of Biostatistics or Epidemiology, have strong quantitative abilities and interest in the curriculum for interdisciplinary training program.

COURSEWORK

Biostatistics

Epidemiology

LAB ROTATIONS

Lab Rotations for Biostatistics Students with Emphasis on Quantitative Genomics

Students are expected to have three lab rotations in the first two years, including a wet lab rotation and two dry lab rotations. Presentations and posters will be given after lab rotations to allow students share their lab rotation experience and research findings.

Wet lab rotation: For the wet lab rotation in molecular biology, students are required to register for NUT 216 (Research Techniques in Molecular Biology) for 2.5 credits. This requires 5-7 hours of work per week for 16 weeks or about 12 hours of work per week for 8 weeks. Students identifies a wet lab which can host the lab rotation. Faculty who can host web lab rotations can be found in the Lab. The wet lab rotation registration form may be found here (PDF version here). The wet lab rotation evaluation form is located here (PDF version here).

Rotation Brochure: Students are encouraged to discuss planning of their wet lab rotation with the coordinator of NUT 216, Dr. Marianne Wessling-Resnick, Professor of Genetics and Complex Diseases, and members of the PQG Executive Committee. This wet lab rotation offer hands-on experimental methods of research in the biological sciences. This experience will help to evolve interests for interdisciplinary dissertation projects as well as the suitability of mentors and research environments. Students perform individualized and original laboratory work, including participation in seminars, journal clubs, and assigned readings.

Dry lab rotations: Students are required to take two dry lab rotations to gain practical experience on the quantitative and computational aspects of designing and analyzing "omics" studies by choosing two out of three types of dry labs: statistical genetics and "omics", bioinformatics and computational biology, and genetic epidemiology. The First-Year Summer Project can be counted towards one lab rotation. During an academic year, students can register for BIO 316 for a dry lab rotation for 2.5 credits, whose hours of work can be found in the previous paragraph. For this dry lab rotation, students are required to two co-mentors, one quantitative scientist and one subject-matter scientist by working on real world problems. This lab rotation can substitute the consulting requirement. Faculty who can host web lab rotations can be found in the Lab Rotation Brochure. Students are encouraged to discuss their dry lab rotations with their advisors and the members of The PQG Executive Committee. The dry lab rotation registration form may be found here (PDF version here). The dry lab rotation evaluation form is located here (PDF version here).

Lab Rotation Procedure: Students are expected to do the three lab rotations in the first two years including summer. The faculty who can host wet and dry lab rotations can be found in the Lab Rotation Brochure. For each lab rotation, students need to fill a Quantitative Genomics Lab Rotation form and submit it to Jelena Follweiler before the rotation, and complete a 2-page report summarizing the activities of the lab rotation after the rotation. The faculty mentors are required to complete a Quantitative Genomics Lab Rotation Evaluation form. The first year summer project can be counted towards one lab rotation but no credit is given. Each of the other two lab rotations is given 2.5 credits.

Students are expected to give a talk in the PQG working Series after each lab rotation.

Lab Rotations for Epidemiology Students with Emphasis on Quantitative Genomics 

Students concentrating in quantitative genomics are expected to have three lab rotations in the first two years, including a wet lab rotation and two dry lab rotations. For each lab rotation, students need to fill a Quantitative Genomics Lab Rotation form and submit it to Jelena Follweiler before the rotation, and complete a 2-page report summarizing the activities of the lab rotation after the rotation. The faculty mentors are required to complete a Quantitative Genomics Lab Rotation Evaluation form.

Wet lab rotation: students are required to register for NUT 216 (Research Techniques in Molecular Biology) for 2.5 credits. This requires 5-7 hours of work per week for 16 weeks or about 12 hours of work per week for 8 weeks. Students identify a wet lab which can host the lab rotation. Faculty who can host web lab rotations can be found in the Lab Rotation Brochure. Students are encouraged to discuss planning of their wet lab rotation with the coordination of Marianne Wessling-Resnick, Professor of Genetics and Complex Diseases, and members of the PQG Executive Committee. This wet lab rotation offer hands-on experimental methods of research in the biological sciences. This experience will help to evolve interests for interdisciplinary dissertation projects as well as the suitability of mentors and research environments. Students perform individualized and original laboratory work, including participation in seminars, journal clubs, and assigned readings. The wet lab rotation registration form may be found here (PDF version here). The wet lab rotation evaluation form is located here (PDF version here).

Dry lab rotations: Students are required to take two dry lab rotations to gain practical experience on the quantitative and computational aspects of designing and analyzing "omics" studies by choosing two out of three types of dry labs: statistical genetics and "omics", bioinformatics and computational biology, and genetic epidemiology. Students should register for EPI 300 for a dry lab rotation for 2.5 credits. For this dry lab rotation, students are required to have two co-mentors, one quantitative scientist and one subject-matter scientist. Students are encouraged to discuss their dry lab rotations with their advisors and the members of The PQG Executive Committee. The dry lab rotation registration form may be found here (PDF version here). The dry lab rotation evaluation form is located here (PDF version here).

FACULTY INDEX

Section 1: Wet Lab Rotation

1.1 Molecular Biology
Andrea Baccarelli
Myles Brown
Martha Bulyk
Barbara Burleigh
Lynda Chin
David Christiani
Immaculata De Vivo
Manoj Duraisingh
Sarah Fortune
Jeffrey Fredberg
Marcia Goldberg
Tiffany Horng
Gökhan Hotamisligil
Curtis Huttenhower
Lester Kobzik
Bruce Kristal
Charles Lee
Chih-Hao Lee
Quan Lu
Brendan Manning
Matthias Marti
Jarrod Marto
James Mitchell
Stephanie Shore
Joseph Sodroski
Daniel Tschumperlin
Marc Vidal
Marianne Wessling-Resnick
Ting Wu

Section 2: Dry Lab Rotations

2.1 Statistical Genetics and "Omics"
Jian Guo
Peter Kraft
Bruce Kristal
Nan Laird
Christoph Lange
Liming Liang
Xihong Lin
Jun Liu
Peter Park
Giovanni Parmigiani
Alkes Price
Soumya Raychaudhuri
Tyler VanderWeele
Marc Vidal
Lee-Jen Wei

2.2 Bioinformatics and Computational Biology
Martha Bulyk
Winston Hide
Curtis Huttenhower
Isaac (Zak) Kohane
Cheng Li
Jun Liu
Xiaole Liu
Matthias Marti
Franziska Michor
Giovanni Parmigiani
John Quackenbush
Soumya Raychaudhuri
Frederick (Fritz) Roth
Shamil Sunyaev
Marc Vidal
Guocheng Yuan

2.3 Genetic Epidemiology
Andrea Baccarelli
Deborah Blacker
David Christiani
Immaculata De Vivo
Frank Hu
David Hunter
Peter Kraft
Edwin Silverman
Joel Schwartz
Scott Weiss
Robert Wright