Current Position: Clinical Development Manager, Biomedical Valley Discoveries
Postdoctoral Fellow: 2005-2008
Hui was supported by a Postdoctoral Fellowship from the LAM Foundation while a member of the Manning Lab.
Menon S, Yecies JL, Zhang HH, Howell JJ, Nicholatos J, Harputlugil E, Bronson RT, Kwiatkowski DJ, Manning BD. Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice. Sci Signal. 2012 Mar 27;5(217):ra24. PMID: 22457330
Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, and Manning BD. Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways. Cell Metab 2011; 14:21-32.
Zhang HH, Huang J, Duvel K, Boback B, Wu S, Squillace RM, Wu CL, and Manning BD. Insulin stimulates adipogenesis through theAkt-TSC2-mTORC1 pathway. PLoS One 2009; 4:e6189.
Zhang HH, Lipovsky AI, Dibble CC, Sahin M, Manning BD. 2006 S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt. Mol Cell 24: 185-97.
Zhang HH, Souza SC, Muller KV, Kraemer FB, Obin MS, Greenberg AS. 2003 Lipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysis. J Biol Chem 2003 Dec 19; 278(51):51535-42.
Zhang HH, Halbleib M, Ahmad Faiyaz, Manganiello VC, Greenberg AS 2002 Tumor necrosis factor alpha stimulates lipolysis in differentiated human adiposities through activation of extra cellular signal-related kinase and elevation of intracellular camp. Diabetes 51: 2929-2935.
Zhang HH, Ego MC, Barnett AH, Kumar S 2001 Dexamethasone inhibits tumor necrosis factor alpha-induced apoptosis and interleukin-1 beta release in human subcutaneous adiposities and preadipocytes. J Clin Endocrinol Metab 86(6): 2817-25.
Zhang HH, Eggo MC, Barnett AH, Kumar S 2000 Tumor necrosis factor-alpha exerts dual effects on human adipose leptin synthesis and release. Mol Cell Endocrinol 159 (1-2): 79-88.
Zhang HH, Eggo MC, Barnett AH, Kumar S 2000 Ceiling culture of mature human adiposities: use in studies of adiposity functions. J Endocrinol 164 (2): 119-28
Zhang HH, Kumar S, Barnett AH, Eggo MC 1999 Intrinsic site-specific differences in the expression of leptin in human adiposities and its anticrime effects on glucose uptake. J Clin Endocrinol Metab 84 (7): 2550-6.