Jingxiang Huang

Jingxiang Huang HJX_defense-1

Current Position: Clinical Resident, Dept. of Pathology, National University Hospital, Singapore

Graduate Student: 2004-2009

Select Publications:

Huang J and Manning BD. The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochemical Journal 2008; 412, 179-90.

Huang J, Dibble CC, Matsuzaki M, and Manning BD. The TSC1-TSC2 complex is required for proper activation of mTOR complex 2. Mol Cell Biol 2008; 28:4104-15.

Huang J and Manning BD. A complex interplay between Akt, TSC2, and the two mTOR complexes. Biochemical Society Transactions 2009; 37:217-22.

Zhang HH, Huang J, Duvel K, Boback B, Wu S, Squillace RM, Wu CL, and Manning BD. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. PLoS One 2009; 4:e6189.

Huang J, Wu S, Wu CL, and Manning BD. Signaling events downstream of mTOR complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors. Cancer Res 2009; 69:6107-14.