Associate Professor of Biostatistics
We develop analysis methods and software for high-throughput microarray and sequencing data, and apply these methods to cancer and neuroscience studies. We use gene expression arrays, SNP arrays, and microRNA platforms for integrative analysis of genomic alteration patterns in human diseases such as cancer. We also develop and maintain the dChip software for microarray analysis, which has been cited more than 1600 times.
Li C, Kim SW, Rai D, Bolla AR, Adhvaryu S, Kinney MC, Robetorye RS, Aguiar RC. Copy number abnormalities, MYC activity and the genetic fingerprint of normal B-cells mechanistically define the microRNA profile of DLBCL. Blood. 2009. 113(26):6681-90. (PubMed, GEO)
Avet-Loiseau H, Li C, Magrangeas F, Gouraud W, Charbonnel C, Harousseau JL, Attal M, Marit G, Mathiot C, Facon T, Moreau P, Anderson KC, Campion L, Munshi NC, Minvielle S. Prognostic Significance of Copy-Number Alterations in Multiple Myeloma. J Clin Oncol. 2009. 27(27):4585-90 (PubMed, PDF, GEO)
Loerch PM†, Lu T†, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA. Evolution of the aging brain transcriptome and synaptic regulation. PloS ONE. 2008; 3(10):e3329. (PubMed, Journal, PDF)
Beroukhim R†, Lin M†, Park Y, Hao K, Zhao X, Garraway LA, Fox EA, Hochberg EP, Mellinghoff IK, Hofer MD, Descazeaud A, Rubin MA, Meyerson M, Wong WH, Sellers WR*, Li C*. Inferring Loss-of-Heterozygosity From Tumor-only Samples Using High-Density Oligonucleotide SNP Arrays. PLoS Computational Biology. 2006; 2(5): e41. (PubMed, PDF)
B.S. in Computer Science, 1995, Beijing Normal University, China
Ph.D. in Statistics, 2001, University of California at Los Angeles