Publications
(By date of submission, * if corresponding author)
2012
12. Tomasetti C*, Dolgopyat D. Cancer as a multi-scale multi-type stochastic dynamical system, in preparation.
11. Tomasetti C*, Mullally A, Parmigiani G, Ebert B. On the effects of JAK2 V617F and TET2 mutations on stem cells dynamics, in preparation.
10. Tomasetti C*, Vogelstein B, Parmigiani G. Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation, Proc Natl Acad Sci USA, published ahead of print January 23, 2013, doi:10.1073/pnas.1221068110.
9. Tomasetti C*, Kantarjian H, Ramchandani R, Jabbour E, Quintas-Cardama A, Parmigiani G, Cortes J. The average baseline BCR-ABL levels are significantly higher in patients with resistance to dasatinib as first-line treatment for early chronic phase chronic myeloid leukemia, submitted.
8. Tomasetti C*, Demetri GD, Parmigiani G. The origin of TKI resistance in GIST, submitted.
2011
7. Tomasetti C*. Stochastic modeling of multiple random genetic mutations under the cancer stem cell hypothesis, Mathematical Population Studies 2012, 19(4):200-213.
6. Tomasetti C*. A new hypothesis: imatinib affects leukemic stem cells in the same way it affects all other leukemic cells, Blood Cancer J 2011, 1:e19; doi:10.1038/bcj.2011.17.
5. Tomasetti C*. On the probability of random genetic mutations for various types of tumor growth, Bulletin of Mathematical Biology 2012, 74(6):1379-1395.
2010
4. Tomasetti C*, Levy D. Role of symmetric and asymmetric division of stem cells in developing drug resistance, Proc Natl Acad Sci USA 2010, 107(39):16766-16771.
3. Galante A, Levy D, Tomasetti C*. A mathematical model for microenvironmental control of tumor growth, IFMBE Proceedings 2010, eds Herold KE, Vossoughi J, Bentley WE, Springer, Berlin, 32.
2. Tomasetti C*, Levy D. Drug resistance always depends on the turnover rate, IFMBE Proceedings 2010, eds Herold KE, Vossoughi J, Bentley WE, Springer, Berlin, 32.
1. Tomasetti C*, Levy D. An elementary approach to modeling drug resistance in cancer, Math Biosci Eng 2010, 7(4):905-918.