2012 Epigenetics Workshop
Workshop: Applying Epigenetics To Epidemiologic Studies
Epigenetic modifications may regulate gene expressions, which are not due to changes in the DNA. Clinical and epidemiologic studies have shown that epigenetic changes influence phenotypic traits and risk of common diseases. Recent advances in high-throughput technologies have enabled large-scale and whole genome investigations of epigenetic markers in human population studies. This workshop will cover: (1) the state-of-the-art technologies to assess epigenetic changes in human biospecimen samples; (2) bioinformatics and analytic tools for managing and analyzing epigenetics data; and (3) the application of epigenetics to epidemiologic studies of complex traits and diseases.
Time: 1:30-5:10 PM, March 13, 2012
Location: Kresge G1, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115
1:30-2:10 pm
DNA methylation linking nurture and nature
Moshe Szyf, Ph.D.
Professor
Department of Pharmacology and therapeutics, McGill University
2:10 - 2:50pm
Tools and methods for the analysis of DNA methylation patterns in cancer and complex diseases
Jörg Tost, Ph.D.
Groupleader Epigenetics
Centre National de Génotypage, France
2:50pm - 3:30pm
Histone tail modifications and gene expression changes from human PBMC exposed to Nickel and Arsenic in vivo
Max Costa, Ph.D.
Professor; Associate Director of NYU Cancer Institute
Departments of Environmental Medicine and Pharmacology
3:30pm - 3:50pm
Coffee Break
3:50pm - 4:30pm
Can the epigenome record your life experiences? Applications to risk factor epidemiology
Andrea Baccarelli, M.D., Ph.D., M.P.H.
Mark and Catherine Winkler Associate Professor of Environmental Epigenetics
Department of Environmental Health and Department of Epidemiology, HSPH
4:30pm - 5:10pm
Statistical analysis of methylation quantitative trait loci and epigenetic networks underlying asthma-related traits
Liming Liang, Ph.D.
Assistant professor of statistical genetics
Department of Epidemiology and Department of Biostatistics, HSPH
5:10 pm
Reception
Sponsors: Harvard TREC (Transdisciplinary Research in Energetics and Cancer Center) and Boston Obesity and Nutrition Research Center (BONRC)
Moderators: Frank Hu, Professor of Nutrition and Epidemiology, HSPH
Liming Liang, Assistant Professor of Statistical Genetics, HSPH