Environment, Epigenetics and Disease

Research Fellow

Department of Environmental Health

665 Huntington Avenue
Building I, Room B26
Boston, MA 02115

My Picture

Diddier Prada, MD, PhD.

Department of Environmental Health

Contact information:

Lab Office
Bldg 1, Rm G11, 665 Huntington Ave, Boston, MA 02115
Phone: (617) 416-2090. E-mail: dipradao@hsph.harvard.edu

Research

I am postdoc in the Laboratory of Environmental Epigenetics, with Dr. Andrea Baccarelli. I am interested in Environmental toxicology, Epigenetics and their relationship with human diseases, especially those age-related. Also, I have been working with air pollution (PM2.5 and black carbon) and Lead (Pb) exposures, evaluating genetic and epigenetic mediators and interactions, especially APOE gene and DNA methylation. I have evaluated its effect on several cardiovascular, neurodegenerative, ophthalmological, endocrine and cancer-related outcomes. Now, I am focused in biological-driven questions that can be applied to epidemiological studies.

Academic background:

  1. MD: Universidad Industrial de Santander, Colombia, 1995-2001.
  2. PhD: Universidad Nacional Autónoma de México, México, 2006-2012.
  3. Postdoc: Harvard T.H. Chan School of Public Health, 2013-date.

Recent publications:

  1. Jia Zhong, Elena Colicino, Xinyi Lin, Amar Mehta, Itai Kloog, Antonella Zanobetti, Hyang-Min Byun, Marie-Abèle Bind, Laura Cantone, Diddier Prada, Letizia Tarantini, Letizia Trevisi, David Sparrow, Pantel Vokonas, Joel Schwartz, and Andrea Baccarelli. Cardiac Autonomic Dysfunction: Particulate Air Pollution Effects are Modulated by Epigenetic Immunoregulation of Toll-like Receptor 2 and Dietary Flavonoid Intake. J Am Heart Ass 2015, 4(1).
  2. Leon-Sarmiento FE, Rizzo-Sierra CV, Leon-Ariza JS, Sobota R, Vera LM, Diddier Prada. A new neurometric assessment of the area-under-curve-associated jiggle of the motor output induced by transcranial magnetic stimulation. Physiology and Behaviour 2015, 141;111-9.
  3. Diddier Prada, Elena Colicino, Melinda C Power, David G Cox, Marc G Weisskopf, Lifang Hou, Avron Spiro III, Pantel Vokonas, Jia Zhong, Marco Sanchez-Guerra, Luis A Herrera, Joel Schwartz, Andrea A. Baccarelli. Influence of multiple APOE genetic variants on cognitive function in a cohort of older men – Results from the Normative Aging Study. BMC Psychiatry 2014, 14:223.
  4. Diddier Prada, Curt Hartleben-Matkin, Rafael Mancilla-Vences. A 4-year retrospective study of add-on therapy to the fixed combination of Dorzolamide/timolol for the treatment of POAG. International Journal of Ophtalmology 2014, 7(2): 300-304.