Chensheng (Alex) Lu

Mark and Catherine Winkler Assistant Professor of Environmental Exposure Biology

Department of Environmental Health

401 Park Drive
Landmark Ctr, Rm 404N
Boston, Massachusetts 02215
cslu@hsph.harvard.edu

Other Affiliations

Harvard NIEHS Center for Environmental Health

Harvard Education and Research Center (ERC) for Occupational Safetyand Health

Harvard University Center for the Environment (HUCE)

Research

My primary research is to use variety ofbiomarkers for assessing human exposures to environmental chemicals in order to facilitate the identification of risk factors, as well as the formation ofhypotheses for the health effects.  One of my current research projects is to integrate exposure biomarkers, physiologically-based pharmacokinetic model and cumulative risk assessment tools for quantifying children’s longitudinalexposure to pesticides via dietaryintakes and its risks by comparing to benchmark doses used by regulatoryagencies.  I am also interested in developing the protein adduct-base biomarker to assess the health effects from exposures to organophospate pesticides.

            I am collaborating extensively with scientists/researchers in the following research projects; 1) children’s longitudinal pesticide exposures with the National Center for Environmental Health Pesticide Laboratory at the Center for Disease Control and Prevention (CDC), 2) pesticide residues in food with Food and Drug Administration regional labs in Atlanta GA and College Park MA, 3) OP-adduct biomarker with Agricultural Health Study, 4) nicotinyl insecticides and bee colonies collapsing disorder with Cornell University, and 5) community-based farmworker housing, exposures and health with Wake Forest University School of Medicine. 

In our Exposure Biology Lab at Harvard School of Public Health, we are developing several analytical methods/biosensors using GC/MS and LC/MS/MS to quantify exposures via the analysis of specimen samples in supporting our research program. The current method developments include multi-pesticide residues in foods and environmental samples, pyrethroids in saliva, bisphenol-A (BPA) and phthalate monoesters in urine, and cholinesterase adducts in red blood cells.

Service 

Ad hoc panel member, US EPA Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)Scientific Advisory Panel,

Ad hoc board member, US EPA Food Quality ProtectionAct (FQPA) Scientific Advisory Board,  

Associate editor, Journal of Exposure Science and Environmental Epidemiology (JESEE),

Associate editor, Environmental Health Perspectives (EHP).

Education

Ph.D., 1996, University of Washington, Seattle WA

M.S., 1990, Rutgers, the State University of New Jersey, New Brunswick, NJ