Publications
Ho I-C, Hodge MR, Rooney JW, and Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973-983, 1996.
Hodge MR, , Chun HJ, Rengarajan J, Alt A, Lieberson R and Glimcher LH. NFAT-driven interleukin-4 transcription potentiated by NIP45. Science 274:1903-1905, 1996.
Kim, J.I., Ho, I-C., Grusby, M.J., and Glimcher, L.H. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity. 10:745-751, 1999.
Reimold AM, Iwakoshi N, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, Glimcher LH. Plasma Cell Differentiation Requires Transcription Factor XBP-1 Nature 412:300-307, 2001.
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, and Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell.100:655-669, 2000
Peng SL, Gerth AJ, Ranger AM, and Glimcher LH. NFATc1 (NFATc, NFAT2) and NFATc2 (NFATp, NFAT1) together control both T and B cell activation and differentiation. Immunity 14:13-20, 2001.
Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP and Glimcher LH. T-bet is essential for Th1 lineage commitment and IFN-g production in CD4 but not CD8 T cells. Science 295:338-342, 2002.
Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FHY, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, DeSanctis GT and Glimcher LH. Mice lacking T-bet spontaneously develop airway changes consistent with human asthma. Science 295:336-338, 2002.
Lee AH, Chu G, Iwakoshi NN, and Glimcher LH. 2005. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J 24(24):4368-4380.
Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, and Glimcher LH. 2006. Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest 116(2):414-21.
Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt G, Iwakoshi NN, Schinzel A, Glimcher LH, and Korsmeyer SJ. 2006. Proapoptotic BAX and BAK Modulate the Unfolded Protein Response Through a Direct Interaction with IRE1-alpha. Science. 312(5773):572-6.
Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, and Glimcher LH. 2006. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science 2006;312(5777):1223-1227.