The most intensive research effort is in environmental epidemiology, especially the delayed effects of developmental exposure to marine contaminants. This research was initiated with Dr. Pal Weihe in the Faroe Islands the mid-1980s, and the prospective birth cohort studies since then developed into international collaborative projects. Neurotoxicity has been the main outcome of interest, but more recent projects have studied general development and immunotoxicity. The results have recently inspired downward revisions of methylmercury exposure limits. Other efforts relate to metal toxicology; biomarker development and validation; endocrine disruption, especially estrogenicity, caused by organochlorine exposures and their possible role as risk factors for breast cancer; and carcinogenicity of exposure to zeolite and other mineral fibers. Occupational health studies have included research on percutaneous absorption of chemicals, carcinogenicity of fluoride exposure, and neurotoxicity of lead. Additional publications are on research ethics, genetic susceptibility, the setting of exposure limits, and the impact of the precautionary principle on prevention and research.
[Appendix to "Developmental Neurotoxicity of Industrial Chemicals"]