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Philippe Grandjean

Adjunct Professor of Environmental Health

Department of Environmental Health

401 Park Drive
Landmark Center Room 3-110 East
Boston, Massachusetts 02215
617.384.8907
pgrand@hsph.harvard.edu

Research

The environmental epidemiology research focuses especially on delayed effects of developmental exposure to environmental chemicals. Studies on marine contaminants were initiated with Dr. Pal Weihe in the Faroe Islands in the mid-1980s; prospective birth cohort studies have emphasized neurotoxicity, while more recent projects have examined  general development and immunotoxicity in birth cohort subjects. The results have inspired downward revisions of methylmercury exposure limits internationally. Other recent studies have targeted age-related functional deficits and degenerative diseases, such as Parkinson's disease and cardiovascular disease, in regard to life-time exposure to methylmercury and persistent lipophilic contaminants. Other efforts relate to metal toxicology; biomarker development and validation; endocrine disruption caused by organochlorine substances; and carcinogenicity of exposure to zeolite and other mineral fibers. Occupational health studies have included research on percutaneous absorption of chemicals, carcinogenicity of fluoride exposure, and neurotoxicity of lead. Additional publications are on research ethics, genetic susceptibility, the setting of exposure limits, and the impact of the precautionary principle on prevention and research.

Appendix to "Developmental Neurotoxicity of Industrial Chemicals" (The Lancet, 2006) 

Conference statement on developmental programming (BCPT, 2008)  

Education

DMSc, 1979, University of Copenhagen
MD, 1974, University of Copenhagen

Other Affiliations

Professor and Chair of Environmental Medicine, University of Southern Denmark, Odense, Denmark; Consultant in Toxicology, National Board of Health, Denmark; Editor, Environmental Health (www.ehjournal.net)

Children's Health and the Environment in the Faroes - The CHEF site provides information about prospective studies of birth cohorts from the Faroe Islands, where exposures to seafood contaminants, such as methylmercury and PCBs, are increased.

Environmental Health: A Global Access Science Source - This open access, online journal publishes papers on all aspects of environmental and occupational medicine and related studies in toxicology and epidemiology. Dr. Grandjean and Professor David Ozonoff are Editors-in-Chief. 

Department of Environmental Medicine, University of Southern Denmark - Dr. Grandjean's other academic affiliation. He is a Professor and Chair of this department.