Publications on NCBI

* = co-first author. ** equal contribution as senior authors.

Ballal SA*, Veiga P*, Fenn K*, Michaud M, KimJH, Gallini C, Glickman JN, Quéré G, Garault P, Béal C, Courtin P, Kulakauskas S, Chapot-Chartier MP, van Hylckama Vlieg JET, Garrett WS.(2015). Host lysozyme-mediated lysis of Lactococcus lactis facilitates delivery of colitis-attenuating superoxide dismutase to inflamed colons, PNAS in press.

Mima K.*, Sukawa Y*., Nishihara R.*, Qian Z.R.*, Yamauchi M.*, Inamura K, Kim SA, Masuda A, Nowak JA, Nosho K, Kostic AD, Giannakis M, Watanabe H, Bullman S, Milner DA, Harris CC, Giovannucci E, Garraway LA, Freeman GJ, Dranoff G, Chan AT**, Garrett WS**, Huttenhower C**, Fuchs CS**, Ogino S**. (2015) Fusobacterium nucleatum and T-cells in colorectal carcinoma. JAMA Oncol. In Press. 

Garrett WS. The Microbiota and Cancer. (2015). Science. 348: 80-86.

Boernigen D, Moon YS, Rahnavard G, Waldron L, McIver L, Shafquat A, Franzosa E, Miropolsky, L, Sweeney C, Morgan XC, Garrett W, Huttenhower C. (2015). A reproducible approach to high-throughput biological dataacquisition and integration. PeerJ. Accepted.

Hold GL and Garrett WS. (2015). Gut microbiota: Microbiota organization- a key to understanding CRC development. Nature Rev Gastroenterol Hep 2015 Feb 17, epub ahead of print.

Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, Enk J, Bar-On Y, Stanietstky-Kaynan N, Coppenhagen-Glazer S, Shussman N, Almogy G, Cuapio A, Hofer E, Mevorach D, Tabib A, Ortenberg R, Markel G, Miklic K, Jonjic S, Brennan C, Garrett WS, Bachrach G, and Mandelboim O. (2015). Binding of the Fap2 protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT protects tumors from immune cell attack. Immunity. 17;42(2):344-55.

Song M, Garrett WS, and Chan AT. (2015). Nutrients, Food, and Colon Cancer Prevention. Gastroenterology. Jan 6. pii: S0016-5085(15)00011-6. doi: 10.1053/j.gastro.2014.12.035. epub ahead of print.

Panikov N.S., Mandalakis M., Dai S., Mulcahy L.R., Fowle W., Garrett W.S., and Karger BL. (2014). Near-zero growth kinestics of Pseudomonas putida deduced from proteomic analysis. Environmental Microbiology. 2014. Aug 3. Epub ahead of print.

Franzosa E.A., Morgan X.C., Segata N., Waldron L., Reyes J., Earl A.M., Giannoukos G., Boylan M., Ciulla D., Gevers D., IzardJ., Garrett W.S., Chan A.T., Huttenhower C. (2014). Relating the metatranscriptome and metagenome of the human gut.Proceedings of the National Academy of Sciences of the United States of America. 111: E2329-38.

Sears C.L. and Garrett W.S. (2014). Microbes, Microbiota, and Colon Cancer. Cell Host and Microbe. 15: 317-328.

Rooks, M.G., Veiga P., Wardwell-Scott L., Segata N., Tickle T. Gallini C., Beal C., Michaud M, van Hylckama-Vlieg JET, Ballal S.A., Morgan X.C., Glickman J.N., Gevers D., Huttenhower C, and Garrett W.S. (2014). Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission. ISME J, Feb. 6. Epub ahead of print.

Kostic, A.D., Chun E., Meyerson, M. and Garrett, W.S. (2013). Microbes and Inflammation in Cancer. Cancer Immunology Research. 1: 150-157.

Kostic, A.D., Chun, E., Robertson, L., Glickman, J.N., Gallini, C.A., Michaud, M., Clancy, T.E., Chung, D.C., Lochhead, P., Hold, G.L., El-Omar, E.N., Brenner D., Fuchs C.S., Meyerson M., and Garrett W.S.(2013). Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor immune microenvironment. Cell Host & Microbe. 14: 207-215. PMC3772512.

Bhatt, A.S., Freeman, S.S., Herrera A.F., Pedamallu C.S., Gevers D., Duke, S., Jung J., Michaud M., Walker B.J., Young S., Earl A.M., Kostic, A.D., Ojesina A.I., Hasserjian R., Ballen, K.K., Chen Y., Soriano, G., Antin J.H., Soiffer R.J., Baden, L.R., Garrett, W.S., Hornick, J.S., Marty, F.M., and Meyersonm M. (2013). Sequence-based discovery of Bradyrhizobium enterica in Cord Colitis Syndrome. New England Journal of Medicine. 369: 517-528. PMC3889161.

Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N. and Garrett, W. S. (2013). The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis. Science. 341(6145): 569-573. PMC3807819.

Bornigen D., Morgan X.C., Franzosa E., Ren B., Ramnik R.J., Garrett W.S., and Huttenhower C. (2013). Functional profiling of the gut microbiome in disease-associate inflammation. Genome Medicine. 5:65. epub. PMC3978847.

Cywes-Bentley, C., Skurnik, D., Zaidi, T., Roux, D., Deoliveira, R. B., Garrett, W. S., Lu, X., O’Malley, J., Kinzel, K., Zaidi, T., Rey, A., Perrin, C., Fichorova, R. N., Kayatani, A. K., Maira-Litràn, T., Gening, M. L., Tsvetkov, Y. E., Nifantiev, N. E., Bakaletz, L. O., Pelton, S. I., Golenbock, D. T. and Pier, G. B. (2013). Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. Proceedings of the National Academy of Sciences of the United States of America, 110(24), E2209-18. PMC3683766.

Garrett, W. S. (2013). Kwashiorkor and the gut microbiota. The New England journal of medicine, 368(18), 1746-7.

Kostic, A. D., Howitt, M. R. and Garrett, W. S. (2013). Exploring host-microbiota interactions in animal models and humans. Genes & development, 27(7), 701-18.

Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, Ojesina AI, Jung J, Bass AJ, Tabernero J, Baselga J, Liu C,Shivdasani RA, Ogino S, Birren BW, Huttenhower C, Garrett WS and Meyerson M. 2011. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. 2012. Genome Research. 22 (2): 292-8.

Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, and Huttenhower C. 2011. Metagenomic Biomarker Discovery and Explanation. Genome Biology, 12(6): R60.

Rooks MG and Garrett WS. Bacteria, food, and cancer. 2011. F1000 Reports. 3: 12 [epub 2011 June 1].

Smith PM and Garrett WS. The gut microbiota and mucosal T cells. 2011. Frontiers in Cellular and Infection Microbiology. 2; 111. [epub 2011 May 26].

Ermann J, Garrett WS, Kuchroo J, Rourida JN, Bleich A, and Glimcher LH. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus. 2011. PNAS. 108:7137-41

Ballal SA, Gallini CA, Segata N, Huttenhower C, Garrett WS. Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts. 2011. Cellular Microbiology. 13(4):508-17,

Wardwell LH, Huttenhower C, and Garrett WS. Current Concepts of the Intestinal Microbiota and the Pathogenesis of Infection. 2011. Clinical Infectious Disease Reports. 13(1): 28-34.

Veiga P, Gallini CV, Beal C, Michaud M, Delaney ML, DuBois A, Khlebnikov, van Hylckama JET, Punit S, Glickman JN, Onderdonk AB, Glimcher LH, and Garrett WS. 2010. A Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. PNAS. 107(42): 18132-7.

Garrett WS, Gallini CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, Punit S, Karlsson M, Bry L, Glickman JN, Gordon JI, Onderdonk AB, and Glimcher LH. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. 2010. Cell Host and Microbe. 8(3): 292-300.

Garrett WS, Gordon JI, and Glimcher LH. Homeostasis and Inflammation in the Intestine. 2010. Cell. 140, 859-70.

Garrett WS and Glimcher LH. T-bet-/- RAG2-/- ulcerative colitis: The role of T-bet as a peacekeeper of host-commensal relationships. 2009. Cytokine. 48(1-2):144-7.

Garrett WS, Punit S, Gallini CA , Michaud M, Zhang Y, Sigrist KS, Lord GM,  Glickman JN, and Glimcher LH. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. 2009.Cancer Cell. 16. 1-12.

Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Ito S, Glickman JN, and Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. 2007. Cell. 131(1): 33-45.

Trombetta ES, Ebersold M, Garrett WS, Pypaert M, and Mellman I. Activation of lysosomal function during dendritic cell maturation. Science. 2003. 299: 1400-3.

Chow A, Toomre D, Garrett WS, and Mellman I. Dendritic cell maturation triggers retrograde transport of MHC class II molecules from lysosomes to the plasma membrane. Nature. 2002. 418: 988-994.

Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett WS, Old LJ, and Mellman I. Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. PNAS. 2002. 99: 10629-34.

Maric M, Balasubramanian A, Phan UT, Dong C, Garrett WS, Cannon KS, Alfonso C, Karlsson L, Flavell RA and Cresswell P. Defective antigen processing in GILT-free mice. Science. 2001. 294: 1361-5.

Garrett WS, Chen LM, Kroschewski R, Ebersold M, Turley SJ, Trombetta ES, Galan JE, and Mellman I. The developmental control of endocytosis in dendritic cells by Cdc42.  Cell. 2000. 102: 325–334.

Turley SJ, Inaba K, Garrett WS, Ebersold M, Unternaehrer J, Steinman RM, and Mellman I.  Transport of peptide-MHC class II complexes in developing dendritic cells.   Science. 2000. 288: 522-7.