* = co-first author. ** equal contribution as senior authors.
Segata N, Baldini F, Pompon J, Garrett WS, Truong DT, Dabiré RK, Diabaté A, Levashina EA, and Catteruccia F. The reproductive tracts of two malaria vectors are populated by a core microbiome and by gender- and swarm-enriched microbial biomarkers. Sci Rep. 2016. 6:24207. doi: 10.1038/srep24207.
Rooks MG and Garrett WS. Gut microbiota, metabolites, and host immunity. Nature Reviews Immunology. 2016. In Press.
Zhang C, Derrien M, Levenez F, Brazeilles R, Ballal SA, Kim J, Degivry MC, Quéré G, Garault P, van Hylckama Vlieg JE, Garrett WS, Doré J, and Veiga P. Ecological robustness of the gut microbiota in response to ingestion of transient food-borne microbes. ISME J. 2016. doi: 10.1038/ismej.2016.13. epub ahead of print.
Howitt MR, Lavoie S, Michaud M, Blum AM, Tran SV, Weinstock JV, Gallini CA, Redding K, Margolskee RF, Osborne LC, Artis D, and Garrett WS. Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science. 2015. 351:1329-33. epub ahead of print.
Ballal SA*, Veiga P*, Fenn K*, Michaud M, Kim JH, Gallini C, Glickman JN, Quéré G, Garault P, Béal C, Courtin P, Kulakauskas S, Chapot-Chartier MP, van Hylckama Vlieg JET, and Garrett WS. Host lysozyme-mediated lysis of Lactococcus lactis facilitates delivery of colitis-attenuating superoxide dismutase to inflamed colons. Proceedings of the National Academy of Sciences of the United States of America. 2015. 112:7803-8. PMCID: PMC4485081.
Mima K*, Sukawa Y*., Nishihara R*, Qian ZR*, Yamauchi M*, Inamura K, Kim SA, Masuda A, Nowak JA, Nosho K, Kostic AD, Giannakis M, Watanabe H, Bullman S, Milner DA, Harris CC, Giovannucci E, Garraway LA, Freeman GJ, Dranoff G, Chan AT**, Garrett WS**, Huttenhower C**, Fuchs CS**, Ogino S**. Fusobacterium nucleatum and T-cells in colorectal carcinoma. JAMA Oncol. 2015. 1:653-61. PMCID: PMC4537376. * = co-first author. ** equal contribution as senior authors.
Garrett WS. The Microbiota and Cancer. Science. 2015. 348:80-86.
Boernigen D, Moon YS, Rahnavard G, Waldron L, McIver L, Shafquat A, Franzosa E, Miropolsky, L, Sweeney C, Morgan XC, Garrett WS, Huttenhower C. A reproducible approach to high-throughput biological data acquisition and integration. PeerJ. 2015. 3:e791. PMCID: PMC4493686.
Hold GL and Garrett WS. Gut microbiota: microbiota organization- a key to understanding CRC development. Nature Rev Gastroenterol Hep. 2015. 12:128-9.
Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, Enk J, Bar-On Y, Stanietstky-Kaynan N, Coppenhagen-Glazer S, Shussman N, Almogy G, Cuapio A, Hofer E, Mevorach D, Tabib A, Ortenberg R, Markel G, Miklic K, Jonjic S, Brennan C, Garrett WS, Bachrach G, and Mandelboim O. Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. Immunity. 2015. 42:344-55. PMCID: PMC4361732.
Song M, Garrett WS, and Chan AT. Nutrients, food, and colon cancer prevention. Gastroenterology. 2015. 148:1244-60.
Panikov NS, Mandalakis M, Dai S, Mulcahy LR, Fowle W, Garrett WS, and Karger BL. Near-zero growth kinestics of Pseudomonas putida deduced from proteomic analysis. Environmental Microbiology. 2014. 17:215-28.
Franzosa EA, Morgan XC, Segata N, Waldron L, Reyes J, Earl AM, Giannoukos G, Boylan M, Ciulla D, Gevers D, Izard J, Garrett WS, Chan AT, and Huttenhower C. Relating the metatranscriptome and metagenome of the human gut. Proceedings of the National Academy of Sciences of the United States of America. 2014. 111:E2329-38. PMCID: PMC4050606.
Sears CL and Garrett WS. Microbes, Microbiota, and Colon Cancer. Cell Host and Microbe. 2014. 15:317-328.
Rooks MG, Veiga P, Wardwell-Scott L, Segata N, Tickle T, Gallini CA, Beal C, Michaud M, van Hylckama-Vlieg JET, Ballal SA, Morgan XC, Glickman JN, Gevers D, Huttenhower C, and Garrett WS. Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission. ISME J. 2014. 8:1403-17. PMCID: PMC4069400.
Kostic AD, Chun E, Meyerson M, and Garrett WS. Microbes and inflammation in cancer. Cancer Immunology Research. 2013. 1:150-157.
Kostic AD, Chun E, Robertson L, Glickman JN, Gallini CA, Michaud M, Clancy TE, Chung DC, Lochhead P, Hold GL, El-Omar EN, Brenner D, Fuchs CS, Meyerson M, and Garrett WS. Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor immune microenvironment. Cell Host & Microbe. 2013. 14:207-215. PMCID: PMC3772512.
Bhatt AS, Freeman SS, Herrera AF, Pedamallu CS, Gevers D, Duke S, Jung J, Michaud M, Walker BJ, Young S, Earl AM, Kostic AD, Ojesina AI, Hasserjian R, Ballen KK, Chen Y, Soriano G, Antin JH, Soiffer RJ, Baden LR, Garrett WS, Hornick JS, Marty FM, and Meyerson M. Sequence-based discovery of Bradyrhizobium enterica in cord colitis Syndrome. The New England Journal of Medicine. 2013. 369:517-528. PMCID: PMC3889161.
Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly-Y M, Glickman JN, and Garrett WS. The microbial metabolites, short-chain fatty acids, regulate colonic treg cell homeostasis. Science. 2013. 341:569-573. PMCID: PMC3807819.
Bornigen D, Morgan XC, Franzosa E, Ren B, Ramnik RJ, Garrett WS, and Huttenhower C. Functional profiling of the gut microbiome in disease-associate inflammation. Genome Medicine. 2013. 5:65. PMCID: PMC3978847.
Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O’Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litràn T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, and Pier GB. Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. Proceedings of the National Academy of Sciences of the United States of America. 2013. 110:E2209-18. PMCID: PMC3683766.
Garrett WS. Kwashiorkor and the gut microbiota. The New England Journal of Medicine. 2013. 368:1746-7.
Kostic AD, Howitt MR, and Garrett WS. Exploring host-microbiota interactions in animal models and humans. Genes & Development. 2013. 27:701-18.
Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, Ojesina AI, Jung J, Bass AJ, Tabernero J, Baselga J, Liu C, Shivdasani RA, Ogino S, Birren BW, Huttenhower C, Garrett WS, and Meyerson M. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Research. 2012. 22:292-8. PMCID: PMC3266036.
Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, and Huttenhower C. Metagenomic biomarker discovery and explanation. Genome Biology. 2011. 12:R60. PMCID: PMC3218848.
Rooks MG and Garrett WS. Bacteria, food, and cancer. F1000 biology reports. 2011. 3:12.
Smith PM and Garrett, WS. The gut microbiota and mucosal T cells. Frontiers in Microbiology. 2011. 2:111. PMCID: PMC3153059.
Ermann J, Garrett WS, Kuchroo J, Rourida K, Glickman JN, Bleich A, and Glimcher LH. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus. Proceedings of the National Academy of Sciences of the United States of America. 2011. 108:7137-41. PMCID: PMC3084042.
Ballal SA, Gallini CA, Segata N, Huttenhower C, and Garrett WS. Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts. Cellular Microbiology. 2011. 13:508-17.
Wardwell LH, Huttenhower C, and Garrett WS. Current concepts of the intestinal microbiota and the pathogenesis of infection. Current infectious disease reports. 2011. 13:28-34. PMCID: PMC3077078.
Veiga P, Gallini CA, Beal C, Michaud M, Delaney ML, DuBois A, Khlebnikov A, van Hylckama Vlieg JE, Punit S, Glickman JN, Onderdonk A, Glimcher LH, and Garrett WS. Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. Proceedings of the National Academy of Sciences of the United States of America. 2010. 107:18132-7. PMCID: PMC2964251.
Garrett WS, Gallini, CA, Yatsunenko T, Michaud M, DuBois A, Delaney ML, Punit S, Karlsson M, Bry L, Glickman JN, Gordon JI, Onderdonk AB, and Glimcher LH. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host & Microbe. 2010. 8:292-300. PMCID: PMC2952357.
Garrett WS, Gordon JI, and Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 2010. 140:859-70. PMCID: PMC2845719.
Garrett WS and Glimcher LH. T-bet-/- RAG2-/- Ulcerative Colitis: the role of T-bet as a peacekeeper of host-commensal relationships. Cytokine. 2009. 48:144-7.
Garrett WS, Punit S, Gallini CA, Michaud M, Zhang D, Sigrist K, Lord GM, Glickman JN, Glimcher LH. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. Cancer Cell. 2009. 16:208-219.
Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, and Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 2007. 131:33-45.
Trombetta ES, Ebersold M, Garrett WS, Pypaert M, Mellman I. Activation of lysosomal function during dendritic cell maturation. Science. 2003. 299:1400-3.
Chow A, Toomre D, Garrett WS, and Mellman I. Dendritic cell maturation triggers retrograde transport of MHC class II molecules from lysosomes to the plasma membrane. Nature. 2002. 418:988-994.
Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett WS, Old LJ, and Mellman I. Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. Proceedings of the National Academy of Sciences of the United States of America. 2002. 99:10629-34.
Maric M, Balasubramanian A, Phan UT, Dong C, Garrett WS, Cannon KS, Alfonso C, Karlsson L, Flavell RA and Cresswell P. Defective antigen processing in GILT-free mice. Science. 2001. 294:1361-5.
Garrett WS, Chen LM, Kroschewski R, Ebersold M, Turley SJ, Trombetta ES, Galan JE and Mellman I. The developmental control of endocytosis in dendritic cells by Cdc42. Cell. 2000. 102:325–334.
Turley SJ, Inaba K, Garrett WS, Ebersold M, Unternaehrer J, Steinman RM, Mellman I. Transport of peptide-MHC class II complexes in developing dendritic cells. Science. 2000. 288:522-7.