Interdisciplinary Training in Genes and the Environment

Preceptors

Alberto Ascherio, MD, DrPH; Professor of Epidemiology and Nutrition.  Causes, risk factors, and biomarkers of susceptibility and early diagnosis of multiple sclerosis, Parkinson’s disease, and amyotrophic lateral sclerosis.

Joseph D. Brain, SD; Cecil K. and Philip Drinker Professor of Environmental Physiology. Function and structure of pulmonary macrophages; deposition and clearance of inhaled particles and responses to them; respiratory infection.

David C. Christiani, MD, MPH; Elkan Blout Professor of Environmental Genetics. Occupational diseases; biomarkers and molecular epidemiology.

Immaculata De Vivo, MPH, PhD; Associate Professor in the Department of Epidemiology.  Mechanisms and future prevention of carcinogenesis.

Douglas Dockery, ScD; Department Chair of Environmental Health. Identification of the chemical and physical characteristics of airborne particles contributing to adverse health effects, studies of the pathways of acute cardiovascular events associated with air pollution exposure to link these epidemiologic findings with toxicologic studies of particle effects; methods development for assessment of air pollution health effects as well as other environmental hazards, including contamination of water supplies.

Russ Hauser, MD, MPH, ScD; Frederick Lee Hisaw Professor of Reproductive Physiology.  Reproductive and developmental epidemiology; effects of endocrine disruptors on male and female reproductive endpoints.

Robert Herrick, ScD; Senior Lecturer of Industrial Hygiene.  Occupational health and exposure assessment in studies of biomarkers and asphalt exposures; estimation of long-term exposures for cancer studies.

Tiffany Horng, PhD; Assistant Professor of Genetics and Complex Diseases. The epigenetics of inflammation.

Gökhan S. Hotamisligil, MD, PhD; Department Chair; James Stevens Simmons Professor of Genetics and Metabolism. Molecular basis of metabolic diseases; studies on regulatory pathways; signal transduction in mammalian cells; biology of fatty-acid binding proteins.

Frank B. Hu, MD, MPH, PhD; Professor of Nutrition and Epidemiology. Diet and physical activity in relation to cardiovascular disease and type-2 diabetes; role of diet and lifestyle in preventing macrovascular complications in diabetics.

David J. Hunter, MPH, SD; Vincent L. Gregory Professor in Cancer Prevention.  Cancer epidemiology; molecular and genetic epidemiology.

Peter Kraft, PhD; Associate Professor of Epidemiology. Genetic epidemiology of complex disease; survival analysis.

Petros Koutrakis, PhD; Professor of Environmental Sciences. Development of human exposure measurement techniques and the investigation of sources, transport, and the fate of air pollutants.

Nan Laird, PhD; Professor of Biostatistics. Development of methodology in statistical genetics, longitudinal studies, missing or incomplete data, and analysis of multiple informant data; analysis of family-based studies in genetics and genetic studies of bipolar disorder, asthma and lung disease.

Christoph Lange, PhD; Associate Professor of Biostatistics. Statistical genetics and generalized linear models; collaborative research in asthma genetics and COPD.

Chih-Hao Lee, PhD; Assistant Professor of Genetics and Complex Diseases. The role of nuclear hormone receptors in metabolic diseases.

Cheng Li, PhD; associate Professor of Biostatistics. Computational biology; genetic network modeling.

Xiaole (Shirley) Liu, PhD; Associate Professor of Biostatistics. Computational genomics, especially sequence analysis related to transcription and translation regulations.

Brendan D. Manning, PhD; Associate Professor of Genetics and Complex Diseases. Signal transduction pathways underlying tumor development and metabolic diseases.

James Mitchell, PhD; Assistant Professor of Genetics and Complex Diseases. DNA repair genes and aging.

John Quackenbush, PhD; Professor of Computational Biology and Bioinformatics. Genomic and computational approaches to study patterns of gene expression in cancer with the goal of elucidating the networks and pathways that are fundamental in the development and progression of the disease.

Eric Rimm, SD; Associate Professor of Epidemiology and Nutrition. Relation of diet to diseases, especially obesity, diabetes, and cardiovascular disease; impact of antioxidants, B vitamins, fiber, and alcohol on serum and genetic markers.

Frank Sacks, MD; Professor of Cardiovascular Disease Prevention. Human lipoprotein metabolism; clinical trials of nutrition and cardiovascular disease; acute and long-term effects of diet on kinetics of lipoproteins in humans.

Joel Schwartz, PhD; Professor of Environmental Epidemiology. Health consequences of exposure to pollutants.

John (Jack) Spengler, PhD; Akira Yamaguchi Professor of Environmental Health and Human Habitation. Exposure assessment for environmental contaminants present in air, water, food, and soil; personal monitoring techniques to study population exposures occurring in homes, offices, schools and during transit.

Helen Suh, PhD; Associate Professor of Environmental Sciences. Assessment of community exposures to particles and toxic gases for studies of heart and lung disease.

Lee-Jen Wei, PhD; Professor of Biostatistics. Design and analysis of clinical trials; repeated measurements analysis; survival analysis.