Portrait_small

Georgios Sotiriou

Research Fellow

Center for Nanotechnology & Nanotoxicology

email: sotiriou@hsph.harvard.edu

 

Research interests

Nanoscale functional materials and devices for biomedical applications

Nanostructured materials show great potential in the biomedical field as they can serve as superior bioimaging contrast agents, diagnostic and therapeutic tools. Antibacterial nanosilver, plasmonic nanosized noble metals, quantum dots, nanophosphors and superparamagnetic nanoparticles constitute some of such functional materials. For example, nanoparticles that emit light light upon excitation (e.g. nanophosphors, quantum dots), superparamagnetic (e.g. Fe2O3) and plasmonic nanoparticles (e.g. Au, Ag) can be used as “nanotools” in bio-applications. Here, we synthesize such nanoparticles and investigate the parameters that influence their properties, targeting superior performance in diagnostics and therapeutic applications. Novel nanoscale systems and devices will be fabricated using such functional materials aiming to tackle specific medical and pharmaceutical problems.

ACS Nano vol. 6, pp. 3888-3897 (2012).

ACS Nano vol. 6, pp. 3888-3897 (2012).

Links

ResearchGate

Selected Publications

From a total of 35 publications, for full list please click the Publications link

 

Statistics

  • Total number of publications: 35 (33 original research articles, 2 reviews)
  • First and/or corresponding authorship: 20
  • Total citations: 727 (ISI Web of Science), 857 (Scopus), 1089 (Google Scholar)
  • h-index: 16 (ISI Web of Science), 16 (Scopus), 18 (Google Scholar)
  • m-index (h-index/active years): 6 (ISI Web of Science), 2.8 (Scopus), 3.0 (Google Scholar)
  • Total IF: 225.3

1.   G.A. Sotiriou, G.D. Etterlin, A. Spyrogianni, F. Krumeich, J-C. Leroux & S.E. Pratsinis. “Plasmonic biocompatible silver-gold alloyed nanoparticles”, Chem. Comm. 50, 13559-13562 (2014). link

2.   G.A. Sotiriou, F. Starsich, A. Dasargyri, M.C. Wurnig, F. Krumeich, A. Boss, J-C. Leroux, S.E. Pratsinis. “Photothermal Killing of Cancer Cells by the Controlled Plasmonic Coupling of Silica-coated Au/Fe2O3 Nanoaggregates”, Adv. Funct. Mater. 24, 2818-2827 (2014). link

Sotiriou_AdvFunctMater_2014_frontispiece small

  • Frontispiece of issue published on 21 May 2014: link
  • Featured in ETH Newslink
  • Featured in IEEE Spectrum: link
  • Featured in InterPharma.ch (in German): link
  • Featured in MedGadget: link
  • Featured in NANOTECH ETC: link
  • Featured in inPharma-Technologist: link
  • Featured in Medizin & Technik (in German): link

3.   G.A. Sotiriou, C. Watson, K.M. Murdaugh, T.H. Darrah, G. Pyrgiotakis, A. Elder, J.D. Brain, P. Demokritou. “Engineering Safer-by-Design, Transparent, Silica-coated ZnO Nanorods with Reduced DNA Damage Potential”, Environ. Sci.: Nano 1, 144-153 (2014). link

Safer ZnO

  • Featured in RSC Chemistry Worldlink
  • Featured in Harvard Gazettelink
  • Featured in HSPH News: link
  • Featured in ASPPH Friday Letters: link
  • Featured in Süddeutsche.de (in German): link

4.   A. Pratsinis, P. Hervella, J-C. Leroux, S.E. Pratsinis, G.A. Sotiriou, “Toxicity of Silver Nanoparticles in Macrophages”, Small 9, 2576-2584 (2013). link

5.   G.A. Sotiriou, C.O. Blattmann, S.E. Pratsinis, “Flexible, Multifunctional, Magnetically Actuated Nanocomposite Films”, Adv. Funct. Mater. 23, 34-41 (2013). link

6.   G.A. Sotiriou, E. Diaz, M. S. Long, J. Godleski, J. Brain, S.E. Pratsinis, P. Demokritou, “A Novel Platform for Pulmonary and Cardiovascular Toxicological Characterization of Inhaled Engineered Nanomaterials”, Nanotoxicology 6, 680-690 (2012). link

7.   G.A. Sotiriou, D. Franco, D. Poulikakos, A. Ferrari, “Optically Stable Biocompatible Flame-Made SiO2-Coated Y2O3:Tb3+ Nanophosphors for Cell Imaging”, ACS Nano 6, 3888–3897 (2012). link

8.   G.A. Sotiriou, A. Hirt, P.-Y. Lozach, A. Teleki, F. Krumeich, S.E. Pratsinis, “Hybrid Silica-coated, Janus-like Plasmonic-Magnetic Nanoparticles”, Chem. Mater. 23, 1985-1992 (2011). link

Chem. Mater. vol. 23, pp. 1985-1992 (2011).

 

Featured in ETH lifelink

 

9.   G.A. Sotiriou, T. Sannomiya, A. Teleki, F. Krumeich, J. Vörös, S.E. Pratsinis, “Non-toxic, Dry-coated Nanosilver for Plasmonic Biosensors”, Adv. Funct. Mater. 20, 4250-4257 (2010). link

Adv. Funct. Mater. vol. 20, pp. 4250-4257 (2010).

 

Frontispiece of issue published on 21 Dec 2010link

 

 

10.   G.A. Sotiriou, S.E. Pratsinis, “Antibacterial Activity of Nanosilver Ions and Particles”, Environ. Sci. Technol. 44, 5649-5654 (2010). link