Publications

Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS.: Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell. 2010 Feb 5;140(3):338-48.

Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS.: Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice. J Clin Invest. 2008 Jul;118(7):2640-50.

Furuhashi M, Tuncman G, Gorgun CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.: Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature. 2007 Jun 21;447(7147):959-65.

Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS.: Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.  Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10741-6.

Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm EB, Hotamisligil GS.: A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6970-5.

Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS.: Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 2004 Oct 15;306(5695):457-61.

Pandey M, Tuncman G, Hotamisligil GS, Samad F.: Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar;162(3):933-41.

Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M and Hotamisligil GS: A Central role for JNK in Obesity and Insulin Resistance. Nature. 2002 Nov 21;420(6913):333-6

Peller S, Yona R, Kopilova Y, Prokocimer M, Goldfinger N, Uysal A, Karabulut HG, Tükün A, Bökesoy I, Tuncman G, Rotter V: Molecular Alterations in the TP53 Gene of Peripheral Blood Cells of Patients With Chronic myeloid Leukemia. Genes, Chromosomes & Cancer, 21:2-7, 1998.

Ali, M., Tuncman G., Cross, N.C.P., Vidailhet, M., Bökesoy, I., Gitzelman, R., and Cox, T.M.”Null Alleles of the Aldolase B gene in a Patient with Hereditary Fructose IntoleranceJournal of Medical Genetics, 31:499-503, 1994.

Tuncman G, Tükün A, Yalaz K., Bökesoy I: A case of Prader Willi Syndrome with del 15q11-13. The Turkish Journal of Pediatrics, 35:333-6,1993