Iain MacLeod

Research Associate

Department of Immunology and Infectious Diseases

Face2 (photo.jpg)

651 Huntington Avenue
FXB, Room 310
Boston, Massachusetts 02115
Phone: 617.432.6667
imacleod@hsph.harvard.edu

 

Essex labHarvard AIDS Initiative / Botswana-Harvard AIDS Institute

Research Interests

  • Molecular basis for the immunostimulatory activity of abacavir.
    Characterization of signaling pathways potentially involved in the stimulation of an inflammatory response during abacavir treatment.

  • Rapid detection of low-level NRTI drug resistance in HIV-1.
    Development of an assay for the analysis of nucleoside analog reverse-transcriptase inhibitor (NRTI) drug resistance in HIV-1 variants in resource-limited settings, with a focus on rapid testing for first-line regimen failures.

  • Immune activation in response to HPV as a risk factor for HIV acquisition and transmission. 
    Identification of the response of dendritic and Langerhans cells to HPV and the relationship between DC maturation and cytokine-mediated regulation of HIV transcription in chronically-infected PBMCs.

Education

Ph.D in Molecular Virology
Dept. of Pathology
University of Cambridge (UK) (2007)


LL.M in International Law
School of Law
University of Glasgow (UK) (2004)

B.Sc in Virology
School of Life Science
University of Glasgow (UK) (2003) / Universitat de Barcelona (2002)