Select Publications

Select Publications

Peng W, Robertson L, Gallinetti J, Mejia P, Vose S, Charlip A, Chu T, Mitchell JR, Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice. Sci Transl Med25 January 2012: Vol. 4, Issue 118, p. 118ra11.

Mitchell JR, Verweij M, Brand K, van de Ven M, Goemaere N, van den Engel S, Chu T, Forrer F, Muller C, de Jong M, van IJcken W, IJzermans JN, Hoeijmakers JH, and de Bruin RW, Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice. Aging Cell, 2009. Volume(1): p. 40-53.

Susa D, Mitchell JR, Verweij M, van de Ven M, Roest H, van den Engel S, Bajema I, Mangundap K, Ijzermans JN, Hoeijmakers JH, and de Bruin RW, Congenital DNA repair deficiency results in protection against renal ischemia reperfusion injury in mice. Aging Cell, 2009. Volume(2): p. 192-200.

van de Ven M, Andressoo JO, Holcomb VB, Hasty P, Suh Y, van Steeg H, Garinis GA, Hoeijmakers JH, and Mitchell JR, Extended longevity mechanisms in short-lived progeroid mice: identification of a preservative stress response associated with successful aging. Mech Ageing Dev, 2007. Volume(1): p. 58-63.

van de Ven M, Andressoo JO, Holcomb VB, von Lindern M, Jong WM, De Zeeuw CI, Suh Y, Hasty P, Hoeijmakers JH, van der Horst GT, and Mitchell JR, Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice. PLoS Genet, 2006. Volume(12): p. e192.

Andressoo JO, Mitchell JR, de Wit J, Hoogstraten D, Volker M, Toussaint W, Speksnijder E, Beems RB, van Steeg H, Jans J, de Zeeuw CI, Jaspers NG, Raams A, Lehmann AR, Vermeulen W, Hoeijmakers JH, and van der Horst GT, An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria. Cancer Cell, 2006. Volume(2): p. 121-32.

Andressoo JO, Jans J, de Wit J, Coin F, Hoogstraten D, van de Ven M, Toussaint W, Huijmans J, Thio HB, van Leeuwen WJ, de Boer J, Egly JM, Hoeijmakers JH, van der Horst GT, and Mitchell JR, Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles. PLoS Biol, 2006. Volume(10): p. e322.

Andressoo JO, Hoeijmakers JH, and Mitchell JR, Nucleotide excision repair disorders and the balance between cancer and aging. Cell Cycle, 2006. Volume(24): p. 2886-8.

Mitchell JR, Hoeijmakers JH, and Niedernhofer LJ, Divide and conquer: nucleotide excision repair battles cancer and ageing. Curr Opin Cell Biol, 2003. Volume(2): p. 232-40.

Collins K and Mitchell JR, Telomerase in the human organism. Oncogene, 2002. Volume(4): p. 564-79.

Mitchell JR and Collins K, Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase. Mol Cell, 2000. Volume(2): p. 361-71.

Mitchell JR, Cheng J, and Collins K, A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3′ end. Mol Cell Biol, 1999. Volume(1): p. 567-76.

Mitchell JR, Wood E, and Collins K, A telomerase component is defective in the human disease dyskeratosis congenita. Nature, 1999. Volume(6761): p. 551-5.