JBL V: Nov. 2002
5th Annual John B. Little Symposium
“Cell Signaling in Radiobiology and Carcinogenesis”
November 1-2, 2002
Friday, November 1, 2002
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WELCOME AND INTRODUCTIONS Dr. John B. Little Harvard School of Public Health Dr. Bruce Demple Harvard School of Public Health |
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John B. Little Award Lecture given by Dr. Philip Hanawalt Stanford University “Mechanisms and Consequences of Transcription Coupled DNA Repair” |
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SESSION I: CELL SURVIVAL AND TRANSFORMATION |
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DISCUSSION LEADER: Dr. Bruce Demple Harvard School of Public Health |
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Dr. Robert Weinberg Whitehead Institute for Biomedical Research “Transformation of Normal Human Cells into Cancer Cells” |
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Dr. Jean Wang University of California, San Diego “DNA Damage and Cell Fate Determination“ |
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Dr. Tyler Jacks MIT Center for Cancer Research “Modeling Cancer in the Mouse“ |
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Dr. Michael Greenberg Children’s Hospital of Boston “Signal Transduction Pathways that Regulate Cell Survival and Oncogenesis” |
Saturday, November 2, 2002
| SESSION II: DNA REPAIR AND RADIATION SIGNALING |
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DISCUSSION LEADER: Jay S. Loeffler Massachusetts General Hospital |
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Dr. David Livingston Dana-Farber Cancer Institute “Functional Analysis of the BRCA1 Gene Product“ |
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Dr. Martin Lavin Queensland Institute of Medical Research “Ataxia Telangiectasia: A Paradigm for Radiosensitivity and Cancer Susceptibility” |
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Dr. Eric Wright University of Dundee “Radiation-induced Signaling and Cellular Interactions In Vivo” |
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Dr. Zhi-Min Yuan Harvard School of Public Health “Contribution of MDMX to DNA Damage-induced p53 Activation” |
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SESSION III: REMODELING, FROM GENES TO CELLS TO ANIMALS |
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DISCUSSION LEADER: Dr. Karl T. Kelsey Harvard School of Public Health |
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Dr. Joan Brugge Harvard Medical School “Morphogenesis and Oncogenesis in Mammary Epithelial Cells” |
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Dr. Peter Jones University of Southern California, Keck School of Medicine “Remodeling of Chromatin and DNA Methylation during Human Carcinogenesis” |
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Dr. Richard Kolesnick Memorial Sloan-Kettering Cancer Center “Role of Membrane Rafts in the Radiation Response” |
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Dr. Mary Ann Stevenson Beth Israel Deaconess Medical Center “The Role of the pkr Gene in the Stabilization of Stress-inducible mRNA” |