11th Annual John B. Little Symposium
“Cell and Genome Stability Mechanisms in Cancer and Other Diseases
October 24-25, 2008
Friday, October 24 2008
| John B. Little Award Lecture given by Lawrence Loeb Ph.D.
Professor, Department of Biochemistry University of Washington “Mutator Phenotype in Human Cancer: Origin and Consequences” |
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Session: I |
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Discussion Leader: Michael Makrigiorgos, Ph.D. Associate Professor of Radiation Oncology, Department of Radiation Oncology Dana-Farber Cancer Institute, Harvard Medical School |
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David E. Fisher, M.D., Ph.D. Professor of Pediatrics/Chairman, Department of Dermatology and Director, Melanoma Program in Medical Oncology, Massachusetts General Hospital Harvard Medical School “UV, Skin Signaling, and Cutaneous Cancer Risk” |
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Frank McKeon, Ph.D. Professor, Department of Cell Biology Harvard Medical School “TAp63: Maintaining the Superiority of the Female Germline” |
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Tanya Paull, Ph.D. Professor, Department of Molecular Genetics and Microbiology University of Texas, Austin “Mre11/Rad50 complexes and DNA double-strand break repair” |
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Craig Peterson, Ph.D. Professor and Vice-Chair, Program in Molecular Medicine, University of Massachusetts Medical School “Chromatin remodeling and genomic integrity” |
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Saturday October 25, 2008 Session II: |
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Discussion Leader: Andrew Grosovsky, Ph.D. Professor of Cell Biology and Toxicology, Department of Biochemistry University of California, Riverside |
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Pamela Silver, Ph.D. Professor, Department of Systems Biology Harvard Medical School “Designing Biological Systems” |
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Myron Goodman, Ph.D. Professor of Chemistry, Head of Molecular and Computational Biology University of Southern California “Better Living Through Hyper-Mutation” |
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Thomas Kunkel, Ph.D. Research Geneticist, National Institute of Environmental Health Sciences, NIH “Division of Labor at Yeast DNA Replication Forks” |
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Graham Walker, Ph.D. Professor, Department of Biology Massachusetts Institute of Technology “Dealing with DNA Problems: Template Lesions and Replication Blocks” |
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Session III: |
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Discussion Leader: Karl Kelsey, M.D. Professor of Community Health, Bio Med Center for Environmental Health and Technology, Brown University |
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Raul Mostoslavsky, Ph.D. Assistant Professor, Harvard Medical School, Assistant Geneticist, MGH Cancer Center, Department of Medicine, Massachusetts General Hospital “The role of the chromatin factor SIRT6 in glucose homeostasis” |
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Brian Dynlacht, Ph.D. Professor in the Department of Pathology, NYU School of Medicine, Director of Genomics Program, NYU Cancer Institute “Regulation of Centrosome Duplication and Genome Stability” |
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Johannes Walter, Ph.D. Associate Professor, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School “Mechanism of DNA Interstrand Cross-Link Repair in S Phase” |