Publications

PubMed-NCBI

  1. Krishnan R, Park JA.Wadsworth S, Seow S, Lee P, Seow A. Cellular biomechanics in drug screening and evaluation: Mechanopharmacology. Trends in Pharmacological Sciences.  2015 Dec 1. pii: S0165-6147(15)00224-2. doi: 10.1016/j.tips.2015.10.005. [Epub ahead of print]
  2. Pegoraro AF, Fredberg JJ, Park JA. Problems in biology with many scales of length: Cell-cell adhesion and cell jamming in collective cellular migration. Experimental Cell Research. 2015 Nov 3. pii: S0014-4827(15)30138-5. doi: 10.1016/j.yexcr.2015.10.036. [Epub ahead of print]
  3. Mitchel JA, Antoniak S, Lee JH, Kim SH, McGill M, Randell SH, Israel E, Shore SA, Mackman N, Park JA. IL-13 augments compressive stress-induced tissue factor expression in human airway epithelial cells. American Journal of Respiratory Cellular and Molecular Biology. Sep 25. 2015 [Epub ahead of print]
  4. Park JA†*, Kim JH*, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R, Burger B, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Unjamming and cell shape in the asthmatic airway epithelium. (†corresponding author, *equally contributed) Nature Materials. Oct. 14(10):1040-8. 2015.        Access the recommendation on F1000Prime   http://f1000.com/prime/725694357?bd=1  
  5. Park JA, Fredberg JJ, Drazen JM. Putting the squeeze on airway epithelia. Physiology. July; 30(4): 293-303, 2015.
  6. Kim JH, Serra-Picamal X, Tambe DT, Zhou EH, Park CY, Sadati M, Park JA, Krishnan R, Gweon B, Millet E, Butler JP, Trepat X, Fredberg JJ. Propulsion and navigation within the advancing monolayer sheet. Nature Materials. 12(9):856-63. 2013.
  7. Park JA, Sharif AS, Shiomi T, Kobzik L, Kasahara DI, Tschumperlin DJ, Voynow JA, Drazen JM. Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice. American Journal of Physiology: Lung Cellular and Molecular Physiology. 304(10):L701-7. 2013.
  8. Park JA, Sharif AS, Tschumperlin DJ, Lau L, Limbrey R, Howarth PH, Drazen JM. TF-bearing exosomes from mechanically-stimulated human bronchial epithelial cells in vitro and in vivo. Journal of Allergy and Clinical Immunology. 130(6):1375-83. 2012.
  9. Marinkovic A, Mih J, Park JA, Liu F, Tschumperlin DJ. Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness. American Journal of Physiology: Lung Cellular and Molecular Physiology. 303(3):L169-80. 2012.
  10. Shiomi T, Tschumperlin DJ, Park JA, Sunnarborg SW, Horiuchi K, Blobel CP, Drazen JM. TACE/ADAM17 mediates mechanotransduction in murine tracheal epithelial cells. American Journal of Respiratory Cellular and Molecular Biology 45(2):376-85. 2011.
  11. Park JA, Drazen JM, Tschumperlin DJ. The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. Journal of Biological Chemistry 285(39): 29817-25, 2010.
  12. Kojic N, Chung E, Kho AT, Park JA, Huang A, So PT, Tschumperlin DJ. An EGFR autocrine loop encodes a slow-reacting but dominant mode of mechanotransduction in a polarized epithelium. FASEB J. 24(5): 1604-15, 2010.
  13. Park JA, Tschumperlin DJ. Chronic intermittent Mechanical Stress Increases MUC5AC Protein Expression. Am J Respir Cell Mol Biol. 41(4): 459-66, 2009.
  14. Park JA, Crews AL, Lampe WR, Fang S, Park J, Adler KB. Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein. American Journal of Pathology. 171(6):1822-30, 2007.
  15. Park JA, Adler KB. Potential therapy for mucus hypersecretion in chronic obstructive pulmonary disease. Zhonghua Yi Xue Za Zhi. 86(41):2890-2, 2006.
  16. Chorley BN, Li Y, Fang S, Park JA, Adler KB. (R)-albuterol elicits anti-inflammatory effects in human airway epithelial cells via iNOS. American Journal of Respiratory Cellular and Molecular Biology. 34(1): 119-127, 2006.
  17. Park JA, He F, Martin LD, Li Y, Chorley BN, Adler KB. Human Neutrophil Elastase Induces Hypersecretion of Mucin from Well-Differentiated Human Bronchial Epithelial Cells in vitro via a Protein Kinase C delta – Mediated Mechanism. American Journal of Pathology. 167(3): 651-661, 2005.

Book Chapter

Park JA, Crews AL, Raiford KL, Adler KB. Chapter 11: Mucus and mucus-secreting cells in chronic obstructive pulmonary disease. Chronic Obstructive Lung Disease. 2nd edition, editors: Norbert Voelkel and William MacNee. p141-151, 2008.