Johanna Lepeule

Research Fellow

Department of Environmental Health

Landmark Center West, Room 404C
401 Park Drive
Boston, Massachusetts 02215


2004:  M.S. Public Health, major in Biostatistics, University Paris-Sud 11

2007:  Ph.D Biology, Veterinary Epidemiology, University Rennes 1


After a PhD in veterinary epidemiology, I came back to human health epidemiology.

My area of interest is the adverse effects of air pollution on health, and more specifically on mortality, reproductive outcomes and respiratory outcomes. I am also interested in studying the mechanisms that link air pollution and health outcomes such as epigenetic marks.


Hampel R, Lepeule J, Schneider A, Bottagisi S, Charles MA, Ducimetière P, Peters A, Slama R. 2011. Short-term impact of ambient air pollution and air temperature on blood pressure among pregnant women. Epidemiology. 22(5):671-679.

Lepeule J, Seegers H, Rondeau V, Robert C, Denoix JM, Bareille N. 2011. Risk factors for the presence and extent of Developmental Orthopaedic Disease in the limbs of young horses: Insights from a count model. Prev Vet Med. 101(1-2):96-106.

Parker JD, Rich DQ, Glinianaia SV, Leem JH, Wartenberg D, Bell ML, Bonzini M, Brauer M, Darrow L, Gehring U, Gouveia N, Grillo P, Ha E, van den Hooven EH, Jalaludin B, Jesdale BM, Lepeule J, Morello-Frosch R, Morgan GG, Slama R, Pierik FH, Pesatori AC, Sathyanarayana S, Seo J, Strickland M, Tamburic L, Woodruff TJ. 2011. The International Collaboration on Air Pollution and Pregnancy Outcomes: initial results. Environ Health Perspect. 119(7):1023-1028.

Slama R, Gräbsch C, Lepeule J, Siroux V, Cyrys J, Sausenthaler S, Herbarth O, Bauer M, Borte M, Wichmann HE, Heinrich J. 2010. Maternal fine particulate matter exposure, polymorphism in xenobiotic-metabolizing genes and offspring birth weight. Reprod Toxicol. 30(4):600-612.

Lepeule J, Caïni F, Bottagisi S, Galineau J, Hulin A, Marquis N, Bohet A, Siroux V, Kaminski M, Charles MA, Slama R; EDEN Mother–Child Cohort Study Group. 2010. Maternal exposure to nitrogen dioxide during pregnancy and offspring birth weight: comparison of two exposure models. Environ Health Perspect. 118(10):1483-1489.

Lepeule J, Bareille N, Robert C, Ezanno P, Valette JP, Jacquet S, Blanchard G, Denoix JM, Seegers H. 2009. Association of growth, feeding practices and exercise conditions with the prevalence of Developmental Orthopaedic Disease in limbs of French foals at weaning. Prev Vet Med. 89(3-4):167-177.

Lepeule J, Bareille N, Valette JP, Seegers H, Jacquet S, Denoix JM, Robert C. 2008. Developmental orthopaedic disease in limbs of foals: between-breed variations in the prevalence, location and severity at weaning. Animal. 2(2):284-291.

Lepeule J, Rondeau V, Filleul L, Dartigues JF. 2006. Cox Models: An alternative method to study short-term effects of air pollution. Environ Health Perspect. 114(12):A690-691.

Lepeule J, Rondeau V, Filleul L, Dartigues JF. 2006. Survival analysis to estimate association between short-term mortality and air pollution. Environ Health Perspect. 114(2):242-247.