Associate Professor of Pathology, HMS

Dr. Godleski’s research focuses upon the pulmonary and systemic responses to inhaled ambient air particles. His studies use cardiac and pulmonary mechanical measurements as well as cell and molecular biologic approaches with inhalation exposure to concentrated ambient air particles. The overall hypothesis is being tested in his laboratory is: Ambient urban air particles are complex mixtures with intrinsic toxicity; particulate exposure results in stimulation of lung receptors, release of reactive oxygen species, and induction of pro-inflammatory mediators that lead to local and systemic effects especially on the cardiovascular system, which ultimately account for epidemiologic associations between adverse health effects and particulate air pollution.

M.D., 1969, University of Pittsburgh