Yerby Postdoctoral Research Fellow
Juan’s interdisciplinary research combines cellular, molecular, and genomic approaches to characterize how epigenetic changes reflect the impact of environmental exposures on human health outcomes. Within his work an important epigenetic modification under study is DNA methylation, which serves to modulate chromatin structure and gene expression. As a Yerby Postdoctoral Research Fellow in the Department of Environmental Health, mentored by Prof. Andrea Baccarelli, Juan is pioneering the use of cell-culture methods and of multiplexed, next-generation sequencing technologies within large epidemiological studies. This novel high-throughput approach offers a powerful, cost-effective method for mapping molecular mechanisms and biomarkers that reflect epigenome-wide reprogramming and health trajectories after environmental exposures. In addition to colleagues at the HSPH Center for Health Bioinformatics, he is actively collaborating with faculty at the Harvard-MIT Broad Institute, the Partners Center for Personalized Genetic Medicine, and the Channing Laboratory at the Brigham and Women’s Hospital.