Himes B, Jiang X, Hu R, Wu A, Lasky-Su J, Klanderman B,Ziniti J, Senter-Sylvia J, Lima J,Irvin C,Peters S, Meyers D, Bleecker E, Kubo M, Tamari M, Nakamura Y, Szefler S, Lemanske R, Zeiger R, Strunk R, Martinez F, Hanrahan J, Koppelman G, Postma P, Nieuwenhuis M, Vonk J, Panettieri R, Carey V, Tantisira K, Litonjua A, Lu Q, Weiss S. (2012) Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet. (accepted)
Nabhan JF, Hu R, Oh R, Cohen S, and Lu Q (2012) Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein.Proc. Natl. Acad. Sci. U.S.A. 109: 4146-4151.PMC3306724
Jiang X, Pan H, Nabhan J, Krishnan R, Koziol-White C, Panettieri R, and Lu Q. (2012) A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and downregulation. FASEB J. 26:1995-2007, PMID: 22278941
Stanfield K, Pilsner J, Lu Q, Wright R, Guilarte T, (2012) Dysregulation of BDNF-TrkB signalingin developing hippocampal neurons by lead (Pb), Toxicol. Sci.127:277-295. PMC3327871
Zhou H, DeLoid G, Browning E, Gregory D, Tan F, Bedugnis A, Imrich A, Koziel H, Kramnik I, Lu Q, Kobzik L. (2012) Genome-wide RNAi screen in IFN-γ-treated human macrophages identifies genes mediating resistance to the intracellular pathogen Francisella tularensis. PLoS One 7(2): e31752. PMC3281001
Oh R, Pan W, Yelcin A, Zhang H, Guilarte T, Hotamisligil G, Christiani D, and Lu Q. (2012) Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress. J. Biol. Chem. 287: 6025-6034.PMC3285369
Zhou X, Baron R, Hardin M, Cho M, Zielinski J, Hawrylkiewicz I, Sliwinski P, Hersh C, Mancini J, Lu K, Thibault D, Donahue A, Klanderman B, Rosner B, Raby B, Lu Q, Geldart A, Layne M, Perrella M, Weiss S, Choi A, Silverman E. (2012) Identification of a chronic obstructive pulmonary disease genetic determinant that regulate HHIP. Hum. Mol. Genet. 21:1325-1335. PMC3284120
Zhou E, Krishna R, Stamer W, Perkumas K, Rajendran K, Nabhan J, Lu Q, Fredberg J, Johnson M. (2012) Mechanical responsiveness of the endothelial cell of Schlemm’s canal. J. R. Soc. Interface, 9(71):1144-55. PMID: 22171066
Chen R, Liliental JE, Kowalski PE, Lu Q, Cohen SN. Regulation of transcription of hypoxia-inducible factor-1α (HIF-1α) by heat shock factors HSF2 and HSF4. Oncogene 2011, 30(22):2570-80. PMID: 21258402
Nabhan JF, Pan H, and Lu Q. (2010) Arrestin domain-containing protein 3 (ARRDC3) recruits the NEDD4 E3 ligase to mediate ubiquitination of the β2-adrenergic receptor, EMBO Rep. 11(8): 650-611. PMC2920442
Piccone M, Feng Y, Chang A, Mosseri R, Lu Q, Kutish G, Lu Z, Burrage T, Gooch C, Rock D, and Cohen SN. Identification of cellular genes affecting the Infectivity of Foot-and-Mouth Disease Virus, J. Virol. 2009; 83(13):6681-8. PMC2698527
Tavassoli A, Lu Q*, Gam J, Pan H, Benkovic SJ, Cohen SN. Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction. ACS Chem Biol. 2008; 19;3(12):757-64. (* co-first author). PMID: 19053244
Wei W, Lu Q, Chaudry GJ, Leppla SH, Cohen SN. The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin.Cell 2006; 124:1141-54. PMID: 16564009
Chang AC, Zsak L, Feng Y, Mosseri R, Lu Q, Kowalski P, Zsak A, Burrage TG, Neilan JG, Kutish GF, Lu Z, Laegreid W, Rock DL, Cohen SN. Phenotype-based identification of host genes required for replication of African Swine Fever Virus. J. Virol. 2006; 80(17):8706-8717. PMC1563864
Lu Q, Wei W, Kowalski PE, Chang AC, Cohen SN. EST-based genome-wide gene inactivation identifies ARAP3 as a host protein mediating cellular susceptibility to anthrax toxin. Proc. Natl. Acad. Sci. USA.2004; 101:17246-51. PMC534609
Lu Q, Hope LW, Brasch M, Reinhard C, Cohen SN. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc. Natl. Acad. Sci. USA. 2003; 100: 7626-7631. PMC164637
Lu Q, Henderson E. Two Tetrahymena G-DNA-binding proteins, TGP1 and TGP3, share novel motifs and may play a role in micronuclear division. Nucleic Acids Res. 2000; 28:2993-3001. PMC102678
Tseng HC, Lu Q, Henderson E, Graves D. Phosphorylated tau can promote tubulin assembly. Proc. Natl. Acad. Sci. USA. 1999; 96:9503-08. PMC22238
Lu Q, Schierer T, Kang SG, Henderson E. Purification, characterization and molecular cloning of TGP1, a novel G-DNA binding protein from Tetrahymena thermophila.Nucleic Acids Res.1998; 26:1613-1620. PMC147456
