Research Interests

Research Interests

 

 

The nutrients have significant effects on a number of vital physiological pathways. Furthermore, a strong link exists between the nutrition trends and a number of common diseases such as cancer, diabetes and atherosclerosis. Our lab approach the molecular basis of these interactions by focusing on fatty acid-mediated transcriptional regulation in cells and the biological role of fatty acid binding proteins (FABP) as lipid chaperones involved in intracellular lipid trafficking.Also our lab have so far demonstrated that FABPs are central to many components of the metabolic syndrome, including obesity, insulin resistance, type 2 diabetes and cardiovascular disease.I am focusing on FABP4 (aP2), which is specific to adipocytes, and working on the new therapeutic approaches and role of secreted aP2 in obesity and diabetes in Dr.Hotamisligil’s lab.