Research Specialist/Lab Manager
morantte [at] hsph.harvard.edu
Publications:
Burkewitz, K., Morantte, I., Weir, H. J. M., Yeo, R., Zhang, Y., Huynh, F. K., Ilkayeva., O. R., Hirschey, M. D., Grant, A. R., and Mair., W. B. Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal. Cell. In Press.
Vilchez, D., Boyer, L., Lutz, M., Merkwirth, C., Morantte, I., Tse, C., Spenser, B., Page, L., Masliah, E., Berggren, W. T., Gage, F. H., Dillin, A. (2013). FOXO4 is necessary for neural differentiation of human embryonic stem cells. Aging Cell 12(3):518-22.
Vilchez, D., Boyer, L., Morantte, I., Lutz, M., Merkwirth, C., Joyce, D., Spencer, B., Page, L., Masliah, E., Berggren, W. T., Gage, F. H., Dillin, A. (2012). Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature 489(7415):304-8.
Vilchez, D., Morantte, I., Liu, Z., Douglas, P. M., Merkwirth, C., Rodrigues, A. P., Manning, G., Dillin, A. (2012). RPN-6 determines C. elegans longevity under proteotoxic stress conditions. (2012). Nature 489(7415):263-8.
Mair, W., Morantte, I., Rodrigues, A., Manning, G., Montminy, M., Shaw, R.J., Dillin, A. (2011). Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature 470(7334):404-8.
Canettieri, G., Franchi, A., Guardia, M. D., Morantte, I., Santaguida, M. G., Harney, J. W., Larsen, P. R., Centanni, M. (2008). Activation of thyroid hormone is transcriptionally regulated by epidermal growth factor in human placenta-derived JEG3 cells. Endocrinology 149(2):695-702.
Serra, C., Palacios, D., Mozzetta, C., Forcales, S. V., Morantte, I., Ripani, M., Jones, D. R, Du, K., Jhala, U. S., Simone, C., Puri, P. L. (2007). Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation. Mol Cell 28(2):200-13.
Herzig, S., Hedrick, S., Morantte, I., Koo, S., and Montminy, M. (2003). CREB controls hepatic lipid metabolism through nuclear hormone receptor PPARgamma. Nature 426(6963):190-3.
Charles, C. H., Luo, G. X., Kohlstaedt, L. A., Morantte, I. G., Gorfain, E., Cao, L., Williams, J. H., and Fang, F. (2003). Prevention of human rhinovirus infection by multivalent fab molecules directed against ICAM-1. Antimicrob Agents Chemother 47(5):1503-8.
Luo, G. X., Kohlstaedt, L. A., Charles, C. H., Gorfain, E., Morantte, I. G., Williams, J. H., and Fang, F. (2003). Humanization of an anti-ICAM-1 antibody with over 50-fold affinity and functional improvement. J Immunolog Methods 275(1-2):31-40.
Canettieri, G., Morantte, I., Guzman, E., Asahara, H., Herzig, S., Anderson, S. D., Yates, J. R., and Montminy, M. (2003). Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex. Nat Struct Biol 10(3):175-81.
