Lab Manager/ Senior Research Assistant
We are looking for a highly motivated individual with significant experience in molecular biology and biochemistry to join our dynamic research team. The lab studies the molecular mechanisms that underlie the aging process, using both mammalian cell culture and C. elegans, in order to develop novel therapies to treat age-related pathologies. The successful candidate will play an integral role in ongoing studies exploring nutritionally regulated signaling pathways in aging. Studies will employ molecular biology, fluorescent microscopy, Western blotting, engineering transgenic strains, quantitative RT-PCR, whole genome transcriptome analysis, and C. elegans longevity assays. The lab manager will be expected to be both an integral part of our team of researchers and support to the PI, actively participating in regular laboratory meetings, discussions, and publications. It is expected that s/he will contribute to the advancement of research projects central to the laboratory while at the same time advancing his or her research skills and development as a scientist. In addition to contributing to research endeavors, the incumbent will also be responsible for managing daily operations of the lab. Management duties will include ordering supplies and reagents, training personnel in specialized laboratory techniques and safety procedures, maintaining laboratory equipment, managing lab collections (plasmids, strains, RNAi library), monitoring all IACUC and COMS protocols, ensuring on target spending of grants and designating lab duties to keep lab running smoothly. For additional information on how to apply please send a cover letter and CV to wmair [at] hsph.harvard.edu
- Bachelors, Masters or PhD in Biology or related field. Highly motivated candidates of all levels are encouraged to apply.
- 5+ years of experience in a research laboratory, including a minimum of one year of management experience.
- Strong technical knowledge and experience in molecular biology, genetics and biochemical techniques.
- Prior experience with C. elegans beneficial but not required.
- High level of initiative and motivation; ability to work independently and with a team
- Excellent communication, organization, time management and record-keeping skills
- Ability to think creatively to solve problems
Students within any of Harvard’s graduate programs are eligible to join the lab. Interested international students or those seeking information on Harvard’s programs with a view to joining the Mair lab should contact the William Mair.
Several rotation projects are available in the laboratory and can be tailored to compliment the specific interests of the student. The lab uses a wide variety of molecular biology and biochemical approaches in both C. elegans and mammalian tissue culture. Commonly used techniques include: molecular cloning, Western blotting, chromatin immunoprecipitations, co-immunoprecipitation, RNA mediate interference, transgenic strain construction via microinjection, quantitative RT-PCR, whole genome expression profiling, fluorescent microscopy and C. elegans longevity analysis.
Student wishing to rotate in the lab should email wmair [at] hsph.harvard.edu to discuss their particular interests.
Postdoctoral positions are available for enthusiastic and driven scientists wishing to study the molecular and genetic mechanisms underlying the aging process, with the goal of utilizing this knowledge to develop novel therapies for age-related pathologies. The lab uses a combination of genetic, molecular and biochemical approaches to study aging in both mammalian cells and C. elegans. Candidates should be highly motivated and have relevant training in molecular biology and biochemical techniques. Prior C. elegans experience is not required. Candidates with a Ph.D and a strong research history as indicated by their publication record are encouraged to apply. Candidates with experience in mammalian systems looking to use those systems to answer questions pertinent to our research are also encouraged to apply.
Please email a letter of interest including your research history, CV and future research interests to the email below. Applicants should outline specifically why they are excited by our research program and what they feel they can contribute our to ongoing efforts. Please note that although funding support is not a prerequisite, all postdocs are expected to apply for individual research fellowships.
Select candidates will be asked to arrange for three letters of references to be submitted independently.
William Mair, Ph.D.
Assistant Professor of Genetics & Complex Diseases
wmair [at] hsph.harvard.edu