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Matthias Marti


Recent publications

Joice, R., Nilsson, S.K., Montgomery, J., Dankwa, S., Egan, E., Morahan, B., Seydel, K.B., Bertuccini, L., Alano, P., Williamson, K.C., Duraisingh, M.T., Taylor, T.E., Milner, D.A., and Marti, M. (2014). Plasmodium falciparum transmission stages accumulate in the human bone marrow. Science Translational Medicine 6, 244re5–244re5.

Aguilar, R., Magallon-Tejada, A., Achtman, A.H., Moraleda, C., Joice, R., Cisteró, P., Li Wai Suen, C.S.N., Nhabomba, A., Macete, E., Mueller, I., Marti, M., Alonso, P.L., Menendez, C., Schofield, L., and Mayor, A. (2014). Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow. Blood 123, 959–966.

Mantel, P.-Y., and Marti, M. (2014). The role of extracellular vesicles in Plasmodium and other protozoan parasites. Cellular Microbiology 16, 344–354.

Joice, R., Narasimhan, V., Montgomery, J., Sidhu, A.B., Oh, K., Meyer, E., Pierre-Louis, W., Seydel, K., Milner, D., Williamson, K., Wiegand, R., Ndiaye, D., Daily, J., Wirth, D., Taylor, T., Huttenhower, C., and Marti, M. (2013). Inferring developmental stage composition from gene expression in human malaria. PLoS Computational Biology 9, e1003392.

Mantel, P.-Y., Hoang, A.N., Goldowitz, I., Potashnikova, D., Hamza, B., Vorobjev, I., Ghiran, I., Toner, M., Irimia, D., Ivanov, A.R., Barteneva, N., and Marti, M. (2013). Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System. Cell Host & Microbe 13, 521–534.

Hanson, K.K., Ressurreição, A.S., Buchholz, K., Prudêncio, M., Herman-ornelas, J.D., Rebelo, M., Beatty, W.L., Wirth, D.F., Hanscheid, T., Moreira, R., Marti, M., and Mota, M.M. (2013). Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins.

Marti, M., and Spielmann, T. (2013). Protein export in malaria parasites: many membranes to cross. Current Opinion in Microbiology 1–7.

Aingaran, M., Zhang, R., Law, S.K., Peng, Z., Undisz, A., Meyer, E., Diez-Silva, M., Burke, T. A, Spielmann, T., Lim, C.T., Suresh, S., Dao, M., and Marti, M. (2012). Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum. Cellular Microbiology 14, 983–993.

Da Cruz, F.P., Martin, C., Buchholz, K., Lafuente-Monasterio, M.J., Rodrigues, T., Sönnichsen, B., Moreira, R., Gamo, F.-J., Marti, M., Mota, M.M., Hannus, M, and Prudencio, M. (2012). Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug. The Journal of Infectious Diseases 205, 1278–1286.

Vorobjev, I. a, Buchholz, K., Prabhat, P., Ketman, K., Egan, E.S., Marti, M., Duraisingh, M.T., and Barteneva, N.S. (2012). Optimization of flow cytometric detection and cell sorting of transgenic Plasmodium parasites using interchangeable optical filters. Malaria Journal 11, 312.

Buchholz, K., Burke, T. a, Williamson, K.C., Wiegand, R.C., Wirth, D.F., and Marti, M. (2011). A high-throughput screen targeting malaria transmission stages opens new avenues for drug development. The Journal of Infectious Diseases 203, 1445–1453.


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2003-2006. Postdoctoral Fellow

WEHI, Melbourne; Dr Alan Cowman

1998-2003. PhD

University of Zurich; Dr Adrian Hehl

1997-1998. Research Fellow

University of Texas at El Paso; Dr Sid Das

1990-1996. Diploma/MSc.

University of Basel; Dr Reto Brun

Associate Professor of Immunology & Infectious Diseases

Department of Immunology & Infectious Diseases,

Harvard School of Public Health


665 Huntington Ave

HSPH Building 1, Room 811

Boston, MA 02115

Office phone: 617.432.4126

Lab Phone: 617.432.2683



IID201: Ecology, Epidemiology, and Control of Important Parasitic Diseases

IID216: Cellular and Molecular Biology of Parasites

Ongoing Research Support

Burroughs Wellcome Award (PI)                 

Investigator in the Pathogenesis of Infectious Diseases: Cellular Communication in Malaria Parasites

Sanofi-Aventis, Innovation Award (Co-PI, Wirth PI)

NIH/NIAID, R01 AI07558 (PI)

NIH/NIAID, R21 AI105328 (PI)

BD Bioscience, Immunology Research award (PI)

Bill and Melinda Gates Foundation, OPP1053604

(Co-Investigator, Wirth PI)    

Completed Research Support

Sanofi-Aventis, Innovation Award (Co-investigator, Wirth PI)

Harvard University, Catalyst (PI)

Harvard School of Public Health,

Career Incubator Fund (PI)

Commonwealth of Massachusetts

Mass Life Sciences Center New

Investigator Research Matching

Grant (PI)

NIH/NIAID, RC1 AI086222-01 (PI)

Bill and Melinda Gates Foundation, Grand Challenges Exploration Grant (PI)

Harvard Medical School, W.F. Milton Fund (PI)