MCH Symposium Abstracts
MCH Symposium Abstracts: Early intervention in low birth weight premature infants and The 25 year follow up of the Brookline Early Education Project
December 2006 saw symposium presentations both by Dr. Marie McCormick, entitled Early intervention in low birth weight premature infants: Results at 18 years of age for the Infant Health and Development Program, and by Dr. Judith Palfrey, entitled The 25 year follow up of the Brookline Early Education Project.
Read abstracts below:
Early intervention in low birth weight premature infants: Results at 18 years of age for the Infant Health and Development Program. (Marie McCormick, MD, ScD)
OBJECTIVE: To assess whether improvements in cognitive and
behavioral development seen in preschool educational programs persist, we
compared those in a multisite randomized trial of such a program over the first
3 years of life (INT) to those with follow-up only (FUO) at 18 months of age.
METHODS: This was a prospective follow-up of the Infant
Health and Development Program at 8 sites heterogeneous for sociodemographic
characteristics. Originally 985 children were randomized to the INT (n = 377)
or FUO (n = 608) groups within 2 birth weight strata: heavier low birth weight
(HLBW; 2001-2499 g) and lighter low birth weight (LLBW; < or = 2000 g).
Primary outcome measures were the Peabody Picture Vocabulary Test (PPVT-III),
reading and mathematics subscales of the Woodcock-Johnson Tests of Achievement,
youth self-report on the Total Behavior Problem Index, and high-risk behaviors
on the Youth Risk Behavior Surveillance System (YRBSS). Secondary outcomes
included Weschler full-scale IQ, caregiver report on the Total Behavior Problem
Index, and caregiver and youth self-reported physical health using the Medical
Outcome Study measure. Assessors were masked as to study status.
RESULTS: We assessed 636 youths at 18 years (64.6% of the
985, 72% of whom had not died or refused at prior assessments). After adjusting
for cohort attrition, differences favoring the INT group were seen on the
Woodcock-Johnson Tests of Achievement in math (5.1 points), YRBSS (-0.7
points), and the PPVT-III (3.8 points) in the HLBW youth. In the LLBW youth,
the Woodcock-Johnson Tests of Achievement in reading was higher in the FUO than
INT group (4.2).
CONCLUSIONS: The findings in the HLBW INT group provide
support for preschool education to make long-term changes in a diverse group of
children who are at developmental risk. The lack of observable benefit in the
LLBW group raises questions about the biological and educational factors that
foster or inhibit sustained effects of early educational intervention
The 25 year follow up of the Brookline Early Education Project(Judith Palfrey, MD)
BACKGROUND.: The Brookline Early Education Project (BEEP)
was an innovative, community-based program that provided health and
developmental services for children and their families from 3 months before
birth until entry into kindergarten. It was open to all families in the town of
Brookline and to families from neighboring Boston, to include a mixture of
families from suburban and urban communities. The goal of the project, which
was administered by the Brookline Public Schools, was to ensure that children
would enter kindergarten healthy and ready to learn.
OBJECTIVE.: Outcome studies of BEEP and comparison children
during kindergarten and second grade demonstrated the program's effectiveness
during the early school years. The goal of this follow-up study was to test the
hypotheses that BEEP participants, in comparison with their peers, would have
higher levels of educational attainment, higher incomes, and more positive
health behaviors, mental health, and health efficacy during the young adult
period.
METHODS.: Participants were young adults who were enrolled
in the BEEP project from 1973 to 1978. Comparison subjects were young adults in
Boston and Brookline who did not participate in BEEP but were matched to the
BEEP group with respect to age, ethnicity, mother's educational level, and
neighborhood (during youth). A total of 169 children were enrolled originally
in BEEP and monitored through second grade. The follow-up sample included a
total of 120 young adults who had participated in BEEP as children. The sample
differed from the original BEEP sample in having a slightly larger proportion
of college-educated mothers and a slightly smaller proportion of urban families
but otherwise resembled the original BEEP sample. The demographic features of
the BEEP and comparison samples were similar. The young adults were asked to
complete a survey that focused on the major domains of educational/functional
outcomes and health/well-being. The study used a quasi-experimental
causal-comparative design involving quantitative analyses of differences
between the BEEP program and comparison groups, stratified according to
community. Hypotheses were tested with analysis of variance and multivariate
analysis of variance techniques. Analyses of the hypotheses included the main
effects of group (BEEP versus comparison sample) and community (suburban versus
urban location), as well as their interaction.
RESULTS.: Young adults from the suburban community had
higher levels of educational attainment than did those in the urban group, with
little difference between the suburban BEEP and comparison groups. In the urban
group, participation in the BEEP program was associated with completing >1
additional year of schooling. Fewer BEEP young adults reported having a low
income (less than $20000); the income differences were accounted for largely by
the urban participants. The percentage of subjects with private health
insurance was significantly lower in the urban group overall, but the BEEP
urban group had higher rates of private insurance than did the comparison
group. More than 80% of both suburban samples reported being in very good or
excellent health; the 2 urban groups had significantly lower ratings, with 64%
of the BEEP group and only 41.67% of the comparison group reaching this
standard. Overall, suburban participants reported more positive health
behaviors, more perceived competence, and less depression. Among the urban
samples, however, participation in BEEP was associated with higher levels of
health efficacy, more positive health behaviors, and less depression than their
peers.