Cytokines
The following papers contain data about cytokines.
Johnston, RA, Mizgerd JP, Flynt L, Quinton LJ, Williams ES, Shore SA. 2007. Type I interleukin-1 receptor is required for pulmonary responses to subacute ozone exposure in mice. Am J Respir Cell Mol Biol 37:477-484.PubMed
Nakahira, M, T Tanaka, BE Robson, JP Mizgerd, MJ Grusby. 2007. Regulation of STAT signaling by the tyrosine phosphatase PTP-BL. Immunity 26:163-176.PubMed
Quinton, LJ, MR Jones, BT Simms, MS Kogan, BE Robson, SJ Skerrett, JP Mizgerd. 2007. Functions and regulation of NF-κB RelA during pneumococcal pneumonia. J. Immunol. 178:1896-1903.PubMed
Prince, AS, JP Mizgerd, J Wiener-Kronish, J Bhattacharya. 2006. Cell signaling underlying the pathophysiology of pneumonia. Am. J. Physiol.: Lung Cell. Mol. Biol. 291:L297-300. PubMed
Yano, K, PC Liaw, JM Mullington, SC Shih, H Okada, N Bodyak, PM Kang, L Toltl, B Belikoff, J Buras, BT Simms, JP Mizgerd, P Carmeliet, SA Karumanchi, WC Aird. 2006. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J. Exp. Med. 203:1447-1458. PubMed
Jones, MR, LJ Quinton, BT Simms, MM Lupa, MS Kogan, JP Mizgerd. 2006. Roles of interleukin-6 in STAT activation and neutrophil recruitment during Escherichia coli pneumonia. J. Infect. Dis. 193:360-369. PubMed
Jones, MR, BT Simms, MM Lupa, MS Kogan, JP Mizgerd. 2005. Lung NF-κB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia. J. Immunol. 175:7530-7535. PubMed
Faffe, DS, L Flynt, M Mellema, PE Moore, ES Silverman, V Subramaniam, MR Jones, JP Mizgerd, T Whitehead, A Imrich, RA Panettieri, Jr, SA Shore. 2005. Oncostatin M causes eotaxin release from airway smooth muscle: synergy with IL-4 and IL-13. J. Allergy Clin. Immunol. 115:514-520. PubMed
Mizgerd, JP. 2004. APC: Braking neutrophils to benefit patients? Blood 104:3841. pdf
Mizgerd, JP, MM Lupa, J Hjoberg, JC Vallone, HB Warren, JP Butler, ES Silverman. 2004. Roles for early response cytokines during E. coli pneumonia revealed by mice with combined deficiencies of all signaling receptors for TNF and IL-1. Am. J. Physiol.: Lung Cell. Mol. Biol. 286:L1302-L1310. PubMed
Wang, Q, CM Doerschuk, JP Mizgerd. 2004. Neutrophils in innate immunity. Semin. Respir. Crit. Care Med. 25:33-42. PubMed
Mizgerd, JP. 2003. Competing benefits of tumor necrosis factor-α for bacteria and for host defense. Am. J. Respir. Crit. Care Med. 168:1410-1411. pdf
Mizgerd, J.P. 2002. Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs. Semin. Immunol. 14:123-132. pdf
Alcamo, E, JP Mizgerd, BH Horwitz, R Bronson, AA Beg, M Scott, CM Doerschuk, RO Hynes, D Baltimore. 2001. Targeted mutation of tumor necrosis factor receptor 1 rescues the RelA-deficient mouse and reveals a critical role for NF-κB in leukocyte recruitment. J. Immunol. 167:1592-1600. pdf
Mizgerd, JP, MR Spieker, CM Doerschuk. 2001. Early response cytokines and innate immunity: essential roles for TNFR1 and IL1R1 during Escherichia coli pneumonia in mice. J. Immunol. 166: 4042-4048. pdf
Mizgerd, JP, JJ Peschon, CM Doerschuk. 2000. Roles of tumor necrosis factor receptor signaling during murine E. coli pneumonia. Am. J. Respir. Cell Mol. Biol. 22: 85-91. pdf
The above Blood articles are copyright of The American Society of Hematology. Others are copyrighted as indicated in the pdf. For articles listing only a PubMed link, we apologize but those publishers denied our request to freely provide pdfs on this web site.
Some cytokines increase vascular permeability in the lungs, as can be seen here. A blue dye was used to identify leaky regions of the lungs during lobar pneumonia.
