Publications
Quinton, LJ, MR Jones, BE Robson, BT Simms, JA Whitsett, JP Mizgerd. 2008. Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia. Am. J. Respir. Cell Mol. Biol. (in press).
Mizgerd, JP. 2008. Acute lower respiratory infection. N. Engl. J. Med. 14:716-27. pdf
Mizgerd, JP, SJ Skerrett. 2008. Animal models of human pneumonia. Am. J. Physiol.: Lung Cell. Mol. Biol. 294:L387-98.pdf
Subramanian, KK, Jia Y, Zhu D, Simms BT, Jo H, Hattori H, You J, Mizgerd JP, Luo HR. 2007. Tumor suppressor PTEN is a physiological suppressor of chemoattractant-mediated neutrophil functions. Blood 109:4028-4037.PubMed
Nakahira, M, T Tanaka, BE Robson, JP Mizgerd, MJ Grusby. 2007. Regulation of STAT signaling by the tyrosine phosphatase PTP-BL. Immunity 26:163-176.PubMed
Quinton, LJ, MR Jones, BT Simms, MS Kogan, BE Robson, SJ Skerrett, JP Mizgerd. 2007. Functions and regulation of NF-κB RelA during pneumococcal pneumonia. J. Immunol. 178:1896-1903.PubMed
Johnston, RA, Mizgerd JP, Flynt L, Quinton LJ, Williams ES, Shore SA. 2007. Type I interleukin-1 receptor is required for pulmonary responses to subacute ozone exposure in mice. Am J Respir Cell Mol Biol 37:477-484.PubMed
Prince, AS, JP Mizgerd, J Wiener-Kronish, J Bhattacharya. 2006. Cell signaling underlying the pathophysiology of pneumonia. Am. J. Physiol.: Lung Cell. Mol. Biol. 291:L297-300. Full text
Yano, K, PC Liaw, JM Mullington, SC Shih, H Okada, N Bodyak, PM Kang, L Toltl, B Belikoff, J Buras, BT Simms, JP Mizgerd, P Carmeliet, SA Karumanchi, WC Aird. 2006. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J. Exp. Med. 203:1447-1458. Full text
Krishnamurthy, VM, LJ Quinton, LA Estroff, SJ Metallo, JM Isaacs, JP Mizgerd, GM Whitesides. 2006. Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide. Biomaterials 27:3663-3674. PubMed
Mizgerd, JP. 2006. Lung infection- A public health priority. PLoS Medicine 3:e76. pdf
Jones, MR, LJ Quinton, BT Simms, MM Lupa, MS Kogan, JP Mizgerd. 2006. Roles of interleukin-6 in STAT activation and neutrophil recruitment during Escherichia coli pneumonia. J. Infect. Dis. 193:360-369. PubMed
Mizgerd, JP. 2005. Transcription Factors: Nuclear Factor-κB and Inhibitory Protein κB. In Encyclopedia of Respiratory Medicine, edited by GJ Laurent and SD Shapiro. Elsevier Limited: Oxford, UK, pp. 265-269.
Jones, MR, BT Simms, MM Lupa, MS Kogan, JP Mizgerd. 2005. Lung NF-κB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia. J. Immunol. 175:7530-7535. Full text
Mizgerd, JP. 2005. Mac-1 mediates migration to lymph nodes. Blood 109:2927-2928. pdf
Faffe, DS, L Flynt, M Mellema, PE Moore, ES Silverman, V Subramaniam, MR Jones, JP Mizgerd, T Whitehead, A Imrich, RA Panettieri, Jr, SA Shore. 2005. Oncostatin M causes eotaxin release from airway smooth muscle: synergy with IL-4 and IL-13. J. Allergy Clin. Immunol. 115:514-520. PubMed
Johnston, R.A., J.P. Mizgerd, S.A. Shore. 2005. CXCR2 is essential for maximal neutrophil recruitment and methacholine responsiveness after ozone exposure. Am. J. Physiol.: Lung Cell. Mol. Biol. 288:L61-L67. Full text
Mizgerd, JP. 2004. APC: Braking neutrophils to benefit patients? Blood 104:3841. pdf
Mizgerd, JP, MM Lupa, MR Spieker. 2004. NF-κB p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation. BMC Immunol. 5:10. pdf
Mizgerd, JP, MM Lupa, J Hjoberg, JC Vallone, HB Warren, JP Butler, ES Silverman. 2004. Roles for early response cytokines during E. coli pneumonia revealed by mice with combined deficiencies of all signaling receptors for TNF and IL-1. Am. J. Physiol. 286:L1302-L1310. Full text
Wang, Q, CM Doerschuk, JP Mizgerd. 2004. Neutrophils in innate immunity. Semin. Respir. Crit. Care Med. 25:33-42. PubMed
Mizgerd, JP. 2003. Competing benefits of tumor necrosis factor- for bacteria and for host defense. Am. J. Respir. Crit. Care Med. 168:1410-1411. pdf
Mizgerd, JP, MM Lupa, MS Kogan, HB Warren, L Kobzik, GP Topulos. 2003. Nuclear factor-κB p50 limits inflammation and prevents lung injury during Escherichia coli pneumonia. Am. J. Respir. Crit. Care Med. 168:810-817. pdf
Mizgerd, JP, MR Spieker, MM Lupa. 2002. Exon truncation by alternative splicing of murine ICAM-1. Physiol. Genomics 12:47-51. Full text
Mizgerd, JP, ML Scott, MR Spieker, CM Doerschuk. 2002. IκB-beta independent regulation of acute inflammatory responses to E. coli lipopolysaccharide in mouse lungs. Am. J. Respir. Cell Mol. Biol. 27:575-582. pdf
Tasaka, S, SE Richer, JP Mizgerd, CM Doerschuk. 2002. Very late antigen-4 in CD18-independent neutrophil emigration during acute bacterial pneumonia in mice. Am. J. Respir. Crit. Care Med. 166:53-60. pdf
Mizgerd, J.P. 2002. Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs. Semin. Immunol. 14:123-132. pdf
Alcamo, E, JP Mizgerd, BH Horwitz, R Bronson, AA Beg, M Scott, CM Doerschuk, RO Hynes, D Baltimore. 2001. Targeted mutation of tumor necrosis factor receptor 1 rescues the RelA-deficient mouse and reveals a critical role for NF-κB in leukocyte recruitment. J. Immunol. 167:1592-1600. pdf
Huang, C, GT De Sanctis, PJ O'Brien, JP Mizgerd, DS Friend, JM Drazen, LF Brass, RL Stevens. 2001. Human mast cell tryptase I: Evaluation of its substrate specificity and demonstration of its importance in bacterial infections of the lung. J. Biol. Chem. 276:26276-26284. pdf
Mizgerd, JP, MR Spieker, CM Doerschuk. 2001. Early response cytokines and innate immunity: essential roles for TNFR1 and IL1R1 during Escherichia coli pneumonia in mice. J. Immunol. 166: 4042-4048. pdf
Horwitz, BH, JP Mizgerd, ML Scott, CM Doerschuk. 2001. Mechanisms of granulocytosis in the absence of CD18. Blood 97: 1578-1583. pdf
Mizgerd, JP, JJ Peschon, CM Doerschuk. 2000. Roles of tumor necrosis factor receptor signaling during murine E. coli pneumonia. Am. J. Respir. Cell Mol. Biol. 22: 85-91. pdf
Mizgerd, JP, BH Horwitz, HC Quillen, ML Scott, CM Doerschuk. 1999. Effects of CD18-deficiency on the emigration of murine neutrophils during pneumonia. J. Immunol. 163: 995-999. pdf
Mizgerd, JP, DC Bullard, MJ Hicks, AL Beaudet, CM Doerschuk. 1999. Chronic Inflammatory Disease Alters Adhesion Molecule Requirements for Acute Neutrophil Emigration in Mouse Skin 1. J. Immunol. 162: 5444-5448. pdf
Palombo, JD, SJ DeMichele, PJ Boyce, EE Lydon, J Liu, Y Huang, RA Forse, JP Mizgerd, BR Bistrian. 1999. Short-term enteral feeding with diets containing eicosapentaenoic and ?-linolenic acids modulates alveolar macrophage fatty acid composition and eicosanoid synthesis without compromising bactericidal functions in rats. Crit. Care Med. 27:1908-1915. PubMed
Doerschuk, CM, JP Mizgerd, H Kubo, L Qin, T Kumasaka. 1999. Adhesion molecules and cellular biomechanical changes in acute lung injury. Chest 116: 37S-43S. Full text
Mizgerd, JP, WM Quinlan, BW LeBlanc, GJ Kutkoski, DC Bullard, AL Beaudet, CM Doerschuk. 1998. Combinatorial requirements for adhesion molecules in mediating neutrophil emigration during bacterial peritonitis in mice. J. Leukoc. Biol. 64: 291-297. pdf
Mizgerd, JP, H Kubo, GJ Kutkoski, SD Bhagwan, K Scharffetter-Kochanek, AL Beaudet, CM Doerschuk. 1997. Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice. J. Exp. Med. 186: 1357-1364. pdf
Mizgerd, JP, BB Meek, GJ Kutkoski, DC Bullard, AL Beaudet, CM Doerschuk. 1996. Selectins and neutrophil traffic: margination and Streptococcus pneumoniae-induced emigration in murine lungs. J. Exp. Med. 184: 639-645. pdf
Mizgerd, JP, RM Molina, RC Stearns, JD Brain, AE Warner. 1996. Gadolinium induces macrophage apoptosis. J. Leukoc. Biol. 59: 189-195. pdf
Mizgerd, JP, L Kobzik, AE Warner, JD Brain. 1995. Effects of sodium concentration on human neutrophil bactericidal functions. Am. J. Physiol. 269: L388-L393. PubMed
Mizgerd, JP, JD Brain. 1995. Reactive oxygen species in the killing of Pseudomonas aeruginosa by human leukocytes. Curr. Microbiol. 31:124-128. PubMed
The above Journal of Experimental Medicine articles are reproduced by copyright permission of The Rockefeller University Press. The Blood articles are copyright of The American Society of Hematology. Others are copyrighted as indicated in the pdf. For articles listing only a PubMed link, we apologize but those publishers denied our request to freely provide pdfs on this web site.
