Nano-scale Hyperspectral Microscopy

Title: Nano-scale Hyperspectral Microscopy

Speaker: Byron J. Cheatham, Senior VP, CytoViva, Inc.

Date: Monday July 22

Time: 10:00 am

Place: Room 1302

Abstract: CytoViva, Inc. provides a patented (US patents No. 7,542,203, 7,564,623) nanoscale optical microscope capability integrated with proprietary hyperspectral imaging. This integrated technology was specifically designed for optical observation, spectral characterization and mapping of nano-materials as they interact with biologicals and composite materials. The patented illumination optics of the microscope system utilizes structured oblique-angle illumination to produce a very high signal-to-noise image. Scatter from nano-scale materials imaged with CytoViva’s structured oblique-angle illumination optics can produce as much as seven times more signal intensity when compared to standard darkfield microscope optics.

Integrated hyperspectral imaging on the microscope enables capture of the unique VNIR reflectance spectra (400nm-1,000nm) of nano-scale materials within a wide range of biological and composite environments at a spectral resolution of 2.5nm. The system creates a hyperspectral image of these samples, enabling the nano-materials to be spectrally characterized and mapped throughout the entire sample.

Today over 250 nano-focused laboratories utilize CytoViva technology for nano-drug delivery, nano-toxicology and nano-materials related research initiatives. Additionally the technology is utilized in certain pathogen related studies.

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