IMG_0989

Christa Watson

Short Bio

Dr. Watson has a BS degree in Cell Biology from North Carolina A&T State University since 1999. In 2004, she obtained her MS degree from North Carolina A&T State University/Wake Forest University, in Cancer Biology with specialty in complementary and alternative medicines for the treatment of cancer. After a brief stint in industry, she obtained her PhD in Energy and Environmental Systems with specialty in Environmental Toxicology in 2011. Currently, she is a Postdoctoral Fellow at Harvard School of Public Health. Her research aim is to investigate the genotoxicity of nanoparticles and novel mechanisms of nanotoxicity in biological systems.

Research Interests

My research interest is the investigation of the nanoparticle mediated DNA damage and mutagenesis. My research endeavors have relied on genomic and proteomic evaluations, in vitro toxicity assessments, in vivo pharmacokinetic studies. My research interest also include:

  • In vivo Magnetometry
  • Nanomedicine
  • Biomaterials

Center Involvement

  1. A high efficiency, high throughput screening assay for engineered nanoparticle mediated DNA damage using the Cometchip technology

Selected Publications

  1. C.Watson, J.Ge, J. Cohen, G. Pyrgiotakis, B. Engleward, P.Demokritou High-Throughput Screening Platform for Engineered Nanoparticle-Mediated Genotoxicity Using CometChip Technology. ACS Nano in press DOI: 10.1021/nn404871p (2014)
  2. E.H. Zhou, C. Watson, R. Pizzo, J. Cohen, Q. Dang, P.M.F. de Barros, C.Y. Park, C.Chen, J.D. Brain, J.P. Butler, J.W. Ruberti, J.J. Fredberg and P. Demokritou. “Assessing the impact of engineered nanoparticles on wound healing using a novel in-vitro bioassay.” Nanomedicine in press (2014).
  3. G. A. Sotiriou, C. Watson, K. M. Murdaugh, T. H. Darrah, G. Pyrgiotakis, A. Elder, J. D. Brain and P. Demokritou. “Engineering Safer-by-Design, Transparent, Silica-coated ZnO Nanorods with Reduced DNA Damage Potential”. Environmental Science: Nano in press, DOI: 10.1039/C3EN00062A (2014). link
  4. G. Pyrgiotakis, J. McDevitt, A. Bordini, E. Diaz, R. Molina, C. Watson, G. Deloid, S. Lenard, N. Fix, Y. Mizuyama, T. Yamauchi, J. Brain and P. Demokritou. “A chemical free, nanotechnology-based method for airborne bacterial inactivation using engineered water nanostructures”. Environmental Science: Nano 1, 15-26 (2014). 
  5. S. Pirela, R. Molina, C. Watson, J. Cohen, D. Bello, P. Demokritou, J. Brain. “Effects of copy center particles on the lungs: A toxicological characterization using a Balb/c mouse model”. Inhalation Toxicology 25, 498-508 (2013). link