Georgios Pyrgiotakis

Short Bio

Dr. George Pyrgiotakis is a Postdoctoral Fellow at the Harvard School of Public Health and acting manager of the Laboratory of Envoronmental Health NanoSciences (LEHNS). His research interests focus on the investigation of nanoparticle toxicity and how it correlates to nanoparticle properties, such as size, surface morphology, shape, porosity, etc.

Dr. Pyrgiotakis completed Postdoctoral research at the Particle Engineering Research Center at the University of Florida (2006-2010). He earned his BS degree in Physics from the University of Crete, in Greece. He completed his MS degree at the University of Florida in Materials Science and Engineering with a concentration in Electronic Materials. He holds a PhD in Materials Science and Engineering (2006) with a specialty in Ceramic Materials from the University of Florida. He has written numerous publications, book chapters and holds one patent.

Research Interests

The main research objective is the investigation of the nano-bio interface and understand the interactions between nanoparticles and cells. Interactions at this level can become determinant in nanotoxicology and nano theragnostics. To facilitate that over the years the various research endeavors have relied on Raman spectroscopy, Atomic Force Microscope, in-vitro and in-vivo (instilation, inhalation) studies. My research interest are expaneded to other scientific topics like:

  • Colloidal stability and surface chemistry
  • Photocatalysis
  • Aerosol Physics
  • Bacteria inactivation

Center Involvement

  1. Particle to particle and particle to cell interactions in physiologic fluids using Atomic Force Microscopy (AFM).
  2. Safe by design: Demonstrating the efficiency of a safer formulation concept for flame-generated engineered nanomaterials (ENMs)
  3. Acute inhalation study of realistic nano scale CeO2 using the Harvard VENGES toxicological platform
  4. A novel method for bacteria inactivation in air and on surfaces using Engineered Water Nanostructures.

Selected Publications

  1. Safer Formulation Concept for Flame-Generated Engineered Nanomaterials. S. Gass, J. M. Cohen, G Pyrgiotakis, G. A. Sotiriou, R. Derk, L. Rojanasakul, S. E. Pratsinis, P. Demokritou, ACS Environmental Science and Technology. – doi:10.1021/sc300152f [pdf]
  2. An in vivo and in vitro toxicological characterization of realistic nanoscale CeO2 inhalation exposures. P. Demokritou , S. Gass, G. Pyrgiotakis, J. M. Cohen, W. Goldsmith, W. McKinney, D. Frazer, J. Y Ma, D. Schwegler-Berry, J.D. Brain, V. Castranova, Nanotoxicology – doi:10.3109/17435390.2012.666576 [pdf]
  3. A novel method for bacterial inactivation using electrosprayed water nanostructures. G. Pyrgiotakis, J. McDevitt, T. Yamauchi and P. Demokritou, Journal of Nanoparticle Research (2012) 14:1027 -doi: 10.1007/s11051-012-1027-x [pdf]
  4. Interactions of Engineered Nanomaterials in Physiological Media and Implications for In Vitro Dosimetry. Cohen, G. Deloid, G. Pyrgiotakis and P. Demokritou, Nanotoxicology – (2012) – doi: 10.3109/17435390.2012.666576 [pdf]
  5. Raman Spectroscopy for Clinical Oncology. M. B. Fenn, P. Xanthopoulos, G. Pyrgiotakis, S. R. Grobmyer, P. M. Pardalos, and L. L. Hench, Advances in Optical Technologies (2012) doi:10.1155/2011/213783 [pdf]