Topic: biostatistics

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First comprehensive atlas of human gene activity released

For immediate release: Wednesday, March 26, 2014 Boston, MA — A large international consortium of researchers has produced the first comprehensive, detailed map of the way genes work across the major cells and tissues of the human body. The findings describe the…

‘Big data’ driving scientific revolution

Raw data on everything from genes to purchasing behaviors can now be collected, stored, and crunched at rates unimaginable just a few years ago. But mining this potential goldmine for scientific research can be a daunting task. Researchers from Harvard School of…

The oddsmaker

[ Spring 2008 ] A math whiz takes on brain cancer, MS, and Alzheimer’s disease.  Rebecca Betensky’s dad worked as a statistician for a global oil company on “credit rating stuff,” she says, so for a long time, she “stayed as far away from…

Our bugs, ourselves

[ Spring 2013 ] Microbes in and on our bodies outnumber human cells 10 to 1—and may determine how we get sick and stay well. The story of public health has largely been a story of conquering infections, from smallpox to syphilis…

The promise of big data

[ Spring/Summer 2012 ] Petabytes of raw information could provide clues for everything from preventing TB to shrinking health care costs—if we can figure out how to use them. Harvard School of Public Health microbiologist Sarah Fortune went to Camden, Maine in…

Projecting MS progression

  To help physicians predict the likelihood that a patient’s multiple sclerosis will advance significantly in the near term, Rebecca Betensky and her collaborators have developed a formula, which they continue to refine. Using data from a small group of patients, they…

HIV/AIDS studies in Africa

[Fall 2013 Centennial issue] The School’s fieldwork in HIV/AIDS, which has received support from the President’s Emergency Plan for AIDS Relief (PEPFAR), the National Institutes of Health, the Bill & Melinda Gates Foundation, NIH, and other private philanthropists, is concentrated in three…

Saving lives by the numbers

In the mid-1980s, HSPH biostatistician Stephen Lagakos enthusiastically chatted up colleagues about a new mode of communicating called email. “He wondered if it would be feasible to set up email among all of us who wanted to exchange ideas about how to prevent and…

Off the cuff: Starting a revolution

[ Fall 2012 ] In May 2012, you resigned from the editorial board of Genomics, protesting the exorbitant subscription fees that scientific journals charge. Researchers and institutions in poor nations often cannot afford to pay and are effectively shut out of new science. You called…