Topic: biostatistics

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The promise of big data

[ Spring/Summer 2012 ] Petabytes of raw information could provide clues for everything from preventing TB to shrinking health care costs—if we can figure out how to use them. Harvard School of Public Health microbiologist Sarah Fortune went to Camden, Maine in…

Projecting MS progression

  To help physicians predict the likelihood that a patient’s multiple sclerosis will advance significantly in the near term, Rebecca Betensky and her collaborators have developed a formula, which they continue to refine. Using data from a small group of patients, they…

HIV/AIDS studies in Africa

[Fall 2013 Centennial issue] The School’s fieldwork in HIV/AIDS, which has received support from the President’s Emergency Plan for AIDS Relief (PEPFAR), the National Institutes of Health, the Bill & Melinda Gates Foundation, NIH, and other private philanthropists, is concentrated in three…

Saving lives by the numbers

In the mid-1980s, HSPH biostatistician Stephen Lagakos enthusiastically chatted up colleagues about a new mode of communicating called email. “He wondered if it would be feasible to set up email among all of us who wanted to exchange ideas about how to prevent and…

Off the cuff: Starting a revolution

[ Fall 2012 ] In May 2012, you resigned from the editorial board of Genomics, protesting the exorbitant subscription fees that scientific journals charge. Researchers and institutions in poor nations often cannot afford to pay and are effectively shut out of new science. You called…

Predicting survival for brain cancer patients

Is it possible to predict survival for patients with oligodendroglioma from aberrations in their DNA? According to a 2006 study by Rebecca Betensky and colleagues, the answer is yes. An analysis of DNA in 93 patients was completed for regions labeled “1p”…

Secrets of sound health

[ Winter 2014 ] Growing up, Francesca Dominici lived about a mile from Ciampino Airport, the second busiest in Rome. As she remembers it, the greatest nuisance from the roar of aircraft over her home was that she couldn’t hear her friends…

Aircraft noise linked with heart problems

For immediate release: Tuesday, October 8, 2013 Boston, MA — Older people exposed to aircraft noise, especially at high levels, may face increased risk of being hospitalized for cardiovascular disease, according to a new study from Harvard School of Public Health (HSPH)…

Expanding access to clinical trial data responsibly

For immediate release: October 21, 2013 Boston, MA – A new report by researchers from Harvard University and others in a working group convened by the Multi-Regional Clinical Trials Center (MRCT) at Harvard proposes recommendations for addressing a problem that has vexed…