Topic: genetics

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‘DNA clock’ can help predict lifespan

Scientists have found a biological clock that can provide clues about how long a person might live. The researchers found that people whose biological age was greater than their true age were more likely to die sooner than those whose biological and…

Cystic fibrosis and arsenic poisoning linked to same damaged protein

A new Harvard T.H. Chan School of Public Health co-authored study provides further evidence linking both arsenic poisoning and the chronic respiratory disease cystic fibrosis (CF) to damage in the CFTR protein. An examination of arsenic-exposed patients in Bangladesh found that they…

Probing genes for disease risk

December 5, 2014 -- New research by Alkes Price, associate professor of statistical genetics at Harvard School of Public Health, and colleagues focuses on new approaches to characterizing and identifying genetic factors in complex disease. What’s the basic finding of your new…

Getting a detailed picture of Ebola

The Broad Institute of Harvard and MIT is now “the world’s most powerful factory for analyzing genes from people and viruses,” according to an article in the New York Times, published December 1, 2014. The article highlighted the work of Pardis Sabeti,…

New insights into mechanism behind tuberous sclerosis complex tumors

Findings by Harvard School of Public Health’s Brendan Manning, professor of genetics and complex diseases, are providing new insights into tuberous sclerosis complex (TSC) — a rare genetic disease that causes the widespread growth of benign tumors — and may ultimately lead…

The ‘incredible possibilities’ of big data

October 27, 2014 -- When Kent Walker’s mother-in-law was diagnosed with a type of brain cancer initially deemed incurable, Walker’s 17-year-old daughter began scouring the Internet for information that might help her grandmother’s cause. She came across an ongoing clinical trial on her…

Cracking Ebola’s genetic code

Pardis Sabeti has been a leader in the effort to analyze Ebola’s genetic code and track its mutations. Sabeti, who is an associate professor in the Department of Immunology and Infectious Diseases at Harvard School of Public Health, associate professor, Center for…