Topic: genetics

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New insights into mechanism behind tuberous sclerosis complex tumors

Findings by Harvard School of Public Health’s Brendan Manning, professor of genetics and complex diseases, are providing new insights into tuberous sclerosis complex (TSC) — a rare genetic disease that causes the widespread growth of benign tumors — and may ultimately lead…

The ‘incredible possibilities’ of big data

October 27, 2014 -- When Kent Walker’s mother-in-law was diagnosed with a type of brain cancer initially deemed incurable, Walker’s 17-year-old daughter began scouring the Internet for information that might help her grandmother’s cause. She came across an ongoing clinical trial on her…

Cracking Ebola’s genetic code

Pardis Sabeti has been a leader in the effort to analyze Ebola’s genetic code and track its mutations. Sabeti, who is an associate professor in the Department of Immunology and Infectious Diseases at Harvard School of Public Health, associate professor, Center for…

Digging for research gold in electronic medical records

September 25, 2014 — For scientists who study rare diseases, hospitals’ vast data banks hold tantalizing potential. Access to anonymized electronic medical records allows researchers to track the progress of a larger group of patients than would be possible in a traditional…

Big data's big visionary

[ Fall 2014 ] As cholera swept through London in the mid-19th century, a physician named John Snow painstakingly drew a paper map indicating clusters of homes where the deadly waterborne infection had struck. In an iconic feat in public health history,…

Outbreak of Ebola virus in Sierra Leone traced to funeral

Ebola spread to Sierra Leone via fourteen women who attended a funeral in Guinea and carried the virus back to Sierra Leone, researchers at the Broad Institute of MIT and Harvard, together with colleagues from West Africa, revealed in a study published August…

The Humanitarian Crisis in Syria

[FORUM VIDEO] This Forum event examined the practicalities and decision-making driving the humanitarian response to the unfolding Syrian conflict.