Topic: tuberculosis

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The nano state

[ Spring 2014 ] Can tiny engineered particles help protect us from infectious disease? Hotel rooms, subway cars, offices, airplanes, cruise ships: to most people, the air they breathe inside these places seems benign, if sometimes stuffy and stale. But viewed through the lens…

Global child TB infection estimates doubled

Approximately one million children contract tuberculosis (TB) annually, with 32,000 suffering from a multi-drug resistant (MDR) strain, according to a new study by Harvard School of Public Health (HSPH) researchers and colleagues. These findings are double previous childhood TB estimates. The study,…

New findings in battle against drug-resistant tuberculosis

Sarah Fortune, Melvin J. and Geraldine L. Glimcher associate professor of immunology and infectious diseases, on why some people infected with some "bad actor" strains of M. tuberculosis are at very high risk of getting drug resistant TB, regardless of whether they…

TB, HIV targeted by student researchers

February 18, 2014 — When people who have been cured of tuberculosis (TB) re-develop the disease, are they relapsing or fighting a new strain? How often should HIV/AIDS patients be tested to see if antiretroviral treatment is working? These questions are being…

Role of lung lesions in tuberculosis explored

For years scientists have sought to unravel the mystery of why about 90% of people infected by Mycobacterium tuberculosis, the bacteria that cause tuberculosis (TB), remain symptom-free for years, while the remaining 10% become sick and may die. A December 15, 2013…

TB superstrains

[ Fall 2008 ] Extensively drug-resistant tuberculosis is research focus Covering 200 square kilometers of arid scrubland in South Africa’s KwaZulu-Natal Province, the rural district of Tugela Ferry seems to swallow its inhabitants, its parched mountain ridges shutting out the world beyond. Within the…

When infection won't quit

[ Spring/Summer 2010 ] TB, AIDS, and malaria are finding new ways to resist treatment Recent headlines paint an insidious trend in infectious disease. In San Francisco, 60 percent of new HIV infections are drug resistant. In Europe and the U.S., a deadly new form of tuberculosis —…

The hard science of saving lives

[Fall 2013 Centennial issue] Understanding the basic biology of infectious disease has been a constant at HSPH since its inception. “We’re one of the few schools of public health that has integrated laboratory science and more classical public health disciplines, such as…

Hope for a needle-free TB vaccine

[ Spring 2008 ] New "dry-spray" technology passes muster in guinea pigs Aiming to make immunization safer and more cost-effective for the developing world, Harvard School of Public Health Dean Barry R. Bloom and two bioengineers at Harvard, David Edwards and doctoral student Yun-Ling Wong, have…

Returning home, with a plan to thwart killer TB

[ Fall 2011 ] In Kenya’s arid Wajir district, across the border from Somalia, attending school is not a given. Though some children learn to read while sitting on the floor in crowded classrooms or gathered on the dusty red ground under…