To submit an initial human research application, log into ESTR and select “Create New Study”. Upload any relevant materials/supporting documents when prompted. Details about how to navigate the IRB online submission system and complete an application are available in the “Study Submission Guide”.
Click on a form/document name in the table below to open the individual form. Save the form to your computer desktop and reopen it before completing.
Research Protocol (click to download form)
Submit this document for any new human research activities via ESTR: irb.harvard.edu (Note that this form is not required for Not Human Subjects Research Requests). The Research Protocol will also need to be updated when requesting modifications where applicable.
Not Human Subjects Research Determination Request (click to download form)
Investigators are responsible for not conducting Human Research without prior IRB review and approval. If investigators have questions about whether an activity is Human Research, contact the IRB office. If an investigator wishes to obtain a written determination, log into ESTR: irb.harvard.edu and select “Create New Study.” (Be prepared to upload the Not Human Subjects Request Form in lieu of a Research Protocol.) For guidance on whether activities constitute Human Subjects Research, click here.
Questions about what to submit? Please contact us.