Pedro Mejia

Yerby Postdoctoral Research Fellow

Department of Genetics and Complex Diseases

655 Huntington Avenue
Building II, Room 127
Boston, MA 02115

Other Affiliations

Department of Immunology and Infectious Diseases

Education

Ph.D., 2006, Université de Rouen & Institut Pasteur, Paris, France

M.S., 2001, Université Pierre et Marie Curie & Insitut Pasteur, Paris, France

Research Interests

Working with Dr. James R. Mitchell in the Department of Genetics & Complex Diseases and Dr. Manoj Durainsingh in the Department of Immunology and Infectious Diseases, I am studying the genetic and molecular basis of the protective effect of reduced protein/energy diets against malaria pathogenesis in experimental models.  In addition, I am researching the effect of nutritional status on the inflammatory response against different insults.

Selected Publications

Select Publications:

Pedro Mejia, Monica Diez-Silva, Fengxin Lu, Alvin Davis III.  “C1-inhibitor interacts with Plasmodium falciparum and protects against experimental severe malaria in mice”.   Molecular Immunology 2008 (45): 4156.

Alvin E. Davis III, Pedro Mejia, Fengxin Lu.  “Biological activities of C1-inhibitor”. Molecular Immunology 2008 (45): 4057-4063.

Druilhe P, Spertini F, Soesoe D, Corradin G, Mejia P, Singh S, Audran R, Bouzidi A, Oeuvray C, Roussilhon C. “A malaria vaccine that elicits in humans antibodies able to kill Plasmodium falciparum”.  PLoS Med. 2005 Nov; 2(11):e344.

Singh S, Soe S, Mejia P, Roussilhon C, Theisen M, Corradin G, Druilhe P.  “Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design”. J Infect Dis. 2004 Sep 1; 190(5):1010-8.

Alvin E. Davis III, Fengxin Lu and Pedro Mejia.  “C1-Inhibitor, a multi-functional serine protease inhibitor.” Thrombosis and Haemostasis 2010 Aug 30;104(5).

Ludovic Arnold, Rajeev Kumar Tyagi, Pedro Mejia, Nico Van Rooijen, Jean-Louis-Pérignon1 and Pierre Druilhe. “Analysis of innate defences against Plasmodium falciparum in immunodeficient mice.” Malar J. 2010 Jul 9;9(1):197.