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Ben Fabry
Publications
Cell Rheology

Alcaraz J, Buscemi L, Grabulosa M, Trepat X, Fabry B, Farré R, Navajas D. Microrheology of human lung epithelial cells measured by atomic force microscopy. Biophys J 84: 2071-2079, 2003. [PDF 138 KB]

Mijailovich SM, Kojic M, Zivkovic M, Fabry B, Fredberg JJ. A finite element model of cell deformation during magnetic bead twisting. J Appl Physiol 93:1429-1436, 2002. [PDF 816 KB]

Butler JP, Tolic-Norrelykke IM, Fabry B, Fredber JJ. Traction fields, moments, and strain energy that cells exert on their surroundings. Am J Physiol Cell Physiol 282:C595–C605, 2002. [PDF 608 KB]

Wang N, Tolic-Nørrelykke IM, Chen J, Mijailovich SM, Butler JP, Fredberg JJ, Stamenovic D. Cell prestress I. Stiffness and prestress are closely associated in adherent contractile cells. Am J Physiol Cell Physiol 282:C606–C616, 2002. [PDF 571 KB]

Latourelle J, Fabry B, J. Fredberg JJ. Dynamic equilibration of airway smooth muscle contraction during physiological loading. J Appl Physiol 92:771–779, 2002. [PDF 250 KB]

Fabry B, Maksym GN, Butler JP, Glogauer M, Navajas D, Fredberg JJ. Scaling the microrheology of living cells. Phys Rev Lett 87:148102, 2001. [PDF PRL online]

Fabry B, Maksym GN, Shore SA, Moore PE, Panettieri Jr. RA, Butler JP, Fredberg JJ. Time course and heterogeneity of contractile responses in cultured human airway smooth muscle cells. J Appl Physiol 91:986-994, 2001. [PDF 424 KB]

Chen J, Fabry B, Schiffrin EL, Wang N. Twisting integrin receptors increases endothelin-1 gene expression in endothelial cells. Am J Physiol Cell Physiol 280:C1475–C1484, 2001. [PDF 592 KB]

Meyer CJ, Alenghat FJ, Rim P, Fong JH, Fabry B, Ingber DE. Mechanical control of cyclic AMP signalling and gene transcription through integrins. Nature Cell Biol 2:666-668, 2000. [PDF 84 KB]

Maksym GN, Fabry B, Butler JP, Navajas D, Tschumperlin DJ, Laporte JD, Fredberg JJ. Mechanical properties of cultured human airway smooth muscle cells from 0.05 to 0.4 Hz. J Appl Physiol 89:1619-1632, 2000. [PDF 333 KB]

Alenghat FJ, Fabry B, Tsai KY, Goldmann WH, Ingber DE. Analysis of Cell Mechanics in Single Vinculin-Deficient Cells Using a Magnetic Tweezer. Biochem Biophys Res Commun 277:93-99, 2000. [PDF 233 KB]

Laporte JD, Moore PE, Abraham JH, Maksym GN, Fabry B, Reynold A. Panettieri RA, Shore SA. Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1 beta. Am J Physiol 277:L943-L951, 1999. [PDF 249 KB]

Fabry B, Maksym GN, Hubmayr RD, Butler JP, Fredberg JJ. Implications of heterogeneous bead behavior on cell mechanical properties measured with magnetic twisting cytometry. Journal of Magnetism and Magnetic Materials 194 :120-125, 1999. [PDF 250 KB], [HTML]

Butler JP, Kelly SM. A model for cytoplasmic rheology consistent with magnetic twisting cytometry. Biorheology 35:193-209, 1998. [PDF 468 KB]

Wang N, Butler JP, Ingber DE.
Mechanotransduction Across the Cell Surface and Through the Cytoskeleton. Science 260 :1124-1127, 1993. [HTML]
Abstracts and Proceedings

Fabry B, Chen J, Hu S, Fredberg JJ, Wang N. Displacement Field of the Cytoskeleton in Response to a Local LoadProceedings of the the Second Joint EMBS/BMES Conference, p. 358, Madison, Omnipress, 2002
PDF-version (168 kB)

Fabry B, Butler JP, Fredberg JJ. Noise temperature determines cytoskeletal (CSK) remodeling in human airway smooth muscle (HASM) cellsAm J Respir Crit Care Med; 165:A671, 2002
PDF-version (158 kB)

Fabry B, Maksym GN, Butler JP, Glogauer M, Navajas D, Fredberg JJ. Is cell rheology governed by a glass transition? In: Kamm R et al. (ed). Proceedings of the 2001 Bioenginering Conference, BED-Vol. 50, New York, American Society of Mechanical Engineers, 2001
PDF-version (108 kB)

Fabry B, Maksym GN, Butler JP, Fredberg JJ. Contractile response of human airway smooth muscle cells in culture. Am J Respir Crit Care Med; 161:A472, 2000
PDF-version (15 KB)

Maksym GN, Fabry B, Fredberg JJ. Stiffening of human airway smooth muscle cells and cytoskeletal reorganization in response to mechanical stimulation and contractile activation. Am J Respir Crit Care Med; 161:A472, 2000
PDF-version (19 KB)

Fabry B, Wang Q, Maksym GN, Butler JP, Doerschuk CM, Fredberg JJ. Measurement of cytoplasmic viscosity in neutrophils between 0.1 Hz and 300 Hz. Molec Biol Cell; 10:381a, 1999
PDF-version (8 KB)

Hubmayr RD, Schroeder MA, Baker TA, Fabry B, Walters BJ. Effects of deforming stress on the apparent stiffness of alveolar epithelial cells. In: Goelet VK et al. (ed). Proceedings of the 1999 Bioengineering Conference, BED -Vol. 42, New York, American Society of Mechanical Engineers, 1999
PDF-version (118 KB)
Other Publications

Haberthür C, Fabry B, Zappe D, Guttmann J. Effects of mechanical unloading/loading on respiratory loop gain and periodic breathing in man. Respir Physiol 1998; 112 :23-36 PDF-version (219 KB)

Guttmann J, Bernhard H, Mols G, Benzing A, Hofmann P, Haberthür C, Zappe D, Fabry B, Geiger K. Respiratory comfort of automatic tube compensation and inspiratory pressure support in conscious humans. Intensive Care Med 1997; 23 :1119-24

Stocker R, Fabry B, Eberhard L, Haberthür C. Support of spontaneous breathing in the intubated patient: automatic tube compensation (ATC) and proportional assist ventilation (PAV). Acta Anaesthesiol Scand (Suppl) 1997; 111 :123-8

Lichtwarck-Aschoff M, Guttmann J, Eberhard L, Fabry B, Birle J, Adolph M. Delayed derecruitment after removal of PEEP in patients with acute lung injury. Acta Anaesthesiol Scand 1997; 41 :675-684

Fabry B, Haberthür C, Zappe D, Guttmann J, Kuhlen R, Stocker R. Breathing pattern and additional work of breathing in spontaneously breathing patients with different ventilatory demands during inspiratory pressure support and automatic tube compensation. Intensive Care Med 1997; 23 :545-552
PDF-version
(302 KB)

Stocker R, Fabry B, Stein S, Zappe D, Trentz O, Haberthür C. Zusätzliche Atemarbeit, Atemmuster und Erkennbarkeit der Extubationsbereitschaft unter inspiratorischer Druckunterstutzung (IPS) und automatischer Tubuskompensation (ATC). Unfallchirurg 1996; 99:764-770.
PDF-version (168 KB)

Fabry B, Guttmann J, Eberhard L, Bauer T, Haberthür C, Wolff G. An analysis of desynchronization between the spontaneously breathing patient and ventilator during inspiratory pressure support. Chest 1995; 107 :1387-1394
PDF-version (746 kB)

Guttmann J, Eberhard L, Fabry B, Bertschmann WE, Zeravik J, Adolph M, Eckart J, Wolff G. Time constant/volume relationship of passive expiration in mechanically ventilated ARDS patients. Eur. Respir J 1995; 8 :114-120

Fabry B, Guttmann J, Eberhard L, Wolff G. Compensation of endotracheal tube resistance in spontaneously breathing patients. Technology and Health Care 1994; 1:281-9 HTML-version

Guttmann J, Eberhard L, Fabry B, Bertschmann W, Wolff G. Continuous calculation of intratracheal pressure in tracheally intubated patients. Anesthesiology 1993; 79:503-513

useful links

Hollis

Hollis Plus

Ovid

PubMed

free science journals (HighWire Press)

Countway Library of Medicine

interlibrary borrowing

online physics journals

arXiv
Editorials and Commentaries

Nature physicsportal highlight on soft glassy rheology of cells (PRL 13 Sept. 2001)

Nature Rev Mol Cell Biol vol 2:789, 2001
Soft Cells

Physical Review Focus Sep 24 2001 A Cellular Glass Menagerie

Scientifc American News in Brief Experiments Reveal How Cells Can Act Like Molten Glass

Boston Globe Oct 02 2001 Health/Science Briefs on soft glassy behavior in cells

TRENDS in Cell Biology Vol.11 No.12 Dec 2001 Cytoplasm through the looking glass

Wissenschaft-online highlight on soft glassy rheology (in German)

J Appl Physiol 91: 984-985, 2001 commentary: Time course and heterogeneity of contractile responses in cultured human airway smooth muscle cells

Hubmayr RD. Biology lessons from oscillatory cell mechanics. J Appl Physiol 89:1617–1618, 2000.